Ribociclib is a kinase inhibitor used to treat adults with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer. It’s given:
Dosage and Side Effects
Take Ribociclib tablets orally with or without food, combined with an aromatase inhibitor or fulvestrant.
Start with a recommended daily dose of 600 mg (three 200 mg tablets) for 21 consecutive days followed by 7 days off treatment.
Adjust or discontinue doses based on individual safety and tolerability.
Common side effects include decreased white blood cells, decreased neutrophils, decreased hemoglobin, infections, nausea, increased liver enzymes, fatigue, decreased platelets, diarrhea, vomiting, headache, and hair loss.
What is Ribociclib?
Ribociclib is a medication used in treating advanced or metastatic breast cancer in certain adult patients. It belongs to a class of drugs called kinase inhibitors.
How does Ribociclib work?
Ribociclib functions by inhibiting certain proteins (CDK4/6) involved in the growth of cancer cells, thereby slowing down or stopping the progression of the cancer.
Who can use Ribociclib?
Ribociclib 200 mg is prescribed for adults:
With hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer.
In combination with specific hormonal therapies as the initial treatment or after progression on prior endocrine therapy.