Initiate treatment with Plerixafor 24 mg/1.2 mL (20 mg/mL) after the patient has taken G-CSF once daily for 4 days. Administer Plerixafor injection approximately 11 hours before initiating each apheresis for up to four (4) successive days. 

The recommended dose of Plerixafor by subcutaneous injection is based on body weight: 

• • For Body Weight Weighing Less Than or Equal to 83 KG: 20 mg fixed dose or 0.24 mg/kg of body. 

• For Body Weight Weighing Greater Than 83 KG: 0.24 mg/kg.

Renal impairment: In case creatinine clearance is ≤50 mL/min, reduce the dose by one-third to 0.16 mg/kg.

The most common plerixafor side effects are diarrhea, headache, nausea, injection site reactions, arthralgia, fatigue, dizziness, and vomiting.

• Serious hypersensitivity reactions, including anaphylactic-type reactions may occur. Observe patients for signs/symptoms of hypersensitivity during and after celrixafor administration for at least 30 Minutes and until clinically stable following completion of each administration.
• For the intention of HSC mobilization, Plerixafor may cause mobilization of leukemic cells and subsequent contamination of the apheresis product. Therefore, this medicine is not intended for HSC mobilization and harvest in patients with leukemia.
• Administration of Plerixafor 24mg injection along with G-CSF may increase circulating leukocytes as well as HSC populations. Evaluate white blood cell (WBC) counts during the administration of Plerixafor. 
• Thrombocytopenia may be observed in patients receiving Mozobil 24 mg treatment. Monitor platelet counts in all the respective patients who receive this medicinal product and then undergo apheresis.
• Cases of splenic enlargement or rupture have been seen following the use of plerixafor along with growth factor G-CSF. Assess individuals receiving plerixafor along with G-CSF who report left upper abdominal pain or scapula or shoulder pain for splenic integrity.

Findings suggest that plerixafor injection 20 mg/ml can cause fetal harm if used by a pregnant woman. Pregnant women of reproductive age or potential should use an appropriate form of contraception during therapy with plerixafor and for 7 days after the final dose.

Is Plerixafor approved by the FDA?

The US FDA approved Plerixafor in December 2008 for mobilizing hematopoietic stem cells (HSCs) from BM for use in autologous transplantation in patients with MM or NHL. 

What class of drug is Plerixafor?

Plerixafor belongs to a class of drugs called hematopoietic stem cell mobilizers. 

How to store Plerixafor?

Plerixafor injection 24 mg/1.2 ml (20 mg/mL) is a sterile, clear, preservative-free solution that comes in a 2mL glass single-dose vial. Store at temperature 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). 

What should one do if someone takes an overdose of Plerixafor?

There is no known specific treatment for an overdose with Plerixafor. If a patient takes an overdose, the patient should be evaluated, and standard supportive treatment applied as required. 

How much does Plerixafor cost in India?

The Plerixafor cost in India is very reasonable and can vary. To procure Plerixafor authentically, you can Call Us: (+91) 8130290915, TOLL-FREE: 1800-889-1064, Or Write Us: query@indiangenericmedicines.com.

Where can I get Plerixafor at the best Price? 

Order Plerixafor at the best price today. We request you to Call/WhatsApp Us: (+91) 8130290915, Or dial our TOLL-FREE Number: 1800-889-1064, Or Write Us: query@indiangenericmedicines.com. We’re fully committed to providing you genuine Plerixafor and the best plerixafor price in India. That is why we’ll match the cost/price of any other existing suppliers/distributors in the market who require a medical prescription.

Is the Plerixafor available in India?

Plerixafor is a (prescription drug, doctor-prescribed medication, or health care professional-prescribed medicine) pharmaceutical drug that can be legally dispensed against a medical prescription.

Plerixafor can be made available through the network of authorized distributors in India. (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune, etc.). 

Can You Send the Plerixafor to Foreign Destination?

Buy plerixafor from India online at the best/lowest price from a leading supplier. Indian Generic Medicines can assist in the delivery of Plerixafor; the doctor prescribed medication to the UK, USA, Canada, Australia, Philippines, Saudi Arabia, Thailand, China, South Africa, Kazakhstan, Zambia, Pakistan, Qatar, Kuwait, Sweden, Hong kong, UAE, Turkey, Malaysia, Sri Lanka, Singapore, Uzbekistan Afghanistan, Japan, Nepal, and many other countries.