{"id":3620,"date":"2023-10-16T06:56:52","date_gmt":"2023-10-16T06:56:52","guid":{"rendered":"https:\/\/indiangenericmedicines.com\/?post_type=product&#038;p=3620"},"modified":"2024-04-22T06:45:55","modified_gmt":"2024-04-22T06:45:55","slug":"sacubitril-valsartan","status":"publish","type":"product","link":"https:\/\/indiangenericmedicines.com\/zh\/misc\/sacubitril-valsartan\/","title":{"rendered":"Sacubitril + Valsartan"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Cidmus 50 mg Tablet <\/span><span style=\"font-weight: 400;\">is a combination of sacubitril, a neprilisin inhibitor, and valsartan, an angiotensin II receptor blocker, and is used to reduce the risk of cardiovascular death and hospitalization for heart failure in adult patients with chronic heart failure. Sacubitril + Valsartan Benefits are most clearly evident in those with left ventricular ejection fraction (LVEF) below normal.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">This therapeutic drug is also used for the treatment of symptomatic heart failure with systemic left ventricular systolic dysfunction in pediatric patients aged 12 months and older. This treatment reduces NT-proBNP and is expected to improve cardiovascular outcomes.<\/span><\/p>\n<hr style=\"width: 100%; text-align: left; margin-left: 0;\" \/>\n<p style=\"text-align: left;\"><strong>Dosage and Side Effects Sacubitril and Valsartan<\/strong><b>:\u00a0<\/b><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">The recommended dosage of Cidmus (Sacubitril and Valsartan) tablets typically depends on the patient&#8217;s condition and medical history. However, the usual starting dose is 49\/51 mg twice daily, which can be increased to a target maintenance dose of 97\/103 mg twice daily, as tolerated by the patient. Patients must follow their healthcare provider&#8217;s instructions regarding dosage adjustments and any specific recommendations tailored to their individual needs.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">The most common side effects of Sacubitril and Valsartan tablets are hyperkalemia, hypotension, cough, dizziness, and renal failure.<\/span><\/p>\n<hr style=\"width: 100%; text-align: left; margin-left: 0;\" \/>\n<p><strong>Warning and Precautions Sacubitril and Valsartan:<\/strong><\/p>\n<ul>\n<li style=\"font-weight: 400; text-align: justify;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cidmus tablets<\/span><span style=\"font-weight: 400;\"> may cause symptomatic hypotension, especially in patients with salt depletion, volume depletion, or receiving high doses of diuretics. Blood pressure should be monitored regularly, and dose adjustments may be necessary.<\/span><\/li>\n<li style=\"font-weight: 400; text-align: justify;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Use caution in patients with renal impairment, as Cidmus tablets can lead to renal dysfunction, including acute renal failure. Monitoring of renal function is recommended, and dose adjustments may be necessary.<\/span><\/li>\n<li style=\"font-weight: 400; text-align: justify;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sacubitril and Valsartan tablets may cause hyperkalemia, especially in patients with renal impairment, diabetes mellitus, or receiving potassium-sparing diuretics, potassium supplements, or salt substitutes containing potassium. Serum potassium levels should be monitored regularly, and appropriate measures should be taken to manage hyperkalemia.<\/span><\/li>\n<li style=\"font-weight: 400; text-align: justify;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Angioedema, including swelling of the face, lips, tongue, and throat, may occur with the use of Cidmus tablets. Patients should be monitored for signs of angioedema, and treatment should be discontinued if angioedema occurs.<\/span><\/li>\n<li style=\"font-weight: 400; text-align: justify;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sacubitril\/Valsartan tablets<\/span><span style=\"font-weight: 400;\"> can cause fetal harm when administered to pregnant women. Pregnancy should be avoided during treatment with these tablets, and effective contraception should be used in women of childbearing potential.<\/span><\/li>\n<li style=\"font-weight: 400; text-align: justify;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Use caution in patients with hepatic impairment, as Sacubitril and Valsartan can lead to hepatic dysfunction, including liver failure. Liver function tests should be monitored regularly, and dose adjustments may be necessary in patients with hepatic impairment.<\/span><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<ul>\n<li><b>Medicine Name-<\/b> <span style=\"font-weight: 400;\">Cidmus<\/span><\/li>\n<li><b>API-<\/b><span style=\"font-weight: 400;\"> Sacubitril and Valsartan<\/span><\/li>\n<li><b>Packaging-<\/b><span style=\"font-weight: 400;\"> Tablets<\/span><\/li>\n<li><b>Strength- <\/b><span style=\"font-weight: 400;\">50 mg<\/span><\/li>\n<li><b>Manufactured by- <\/b><span style=\"font-weight: 400;\">Dr Reddy&#8217;s Laboratories Ltd<\/span><\/li>\n<\/ul>","protected":false},"featured_media":4614,"template":"","meta":[],"product_brand":[],"product_cat":[31],"product_tag":[321,557],"class_list":["post-3620","product","type-product","status-publish","has-post-thumbnail","product_cat-misc","product_tag-buy-sacubitril-valsartan-tablets","product_tag-cidmus-50-mg-tablets-price","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/indiangenericmedicines.com\/zh\/wp-json\/wp\/v2\/product\/3620","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/indiangenericmedicines.com\/zh\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/indiangenericmedicines.com\/zh\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/indiangenericmedicines.com\/zh\/wp-json\/wp\/v2\/media\/4614"}],"wp:attachment":[{"href":"https:\/\/indiangenericmedicines.com\/zh\/wp-json\/wp\/v2\/media?parent=3620"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/indiangenericmedicines.com\/zh\/wp-json\/wp\/v2\/product_brand?post=3620"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/indiangenericmedicines.com\/zh\/wp-json\/wp\/v2\/product_cat?post=3620"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/indiangenericmedicines.com\/zh\/wp-json\/wp\/v2\/product_tag?post=3620"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}