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Pazopanib

  • Medicine name- Votrient
  • API- Pazopanib hydrochloride
  • Packaging- Tablets
  • Pack Size- 30 Tablets
  • Strength- 200 mg & 400 mg
  • Manufactured By: Glaxosmithkline
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Description

  • A strong and specific multi-targeted receptor tyrosine kinase inhibitor, Pazopanib tablet is prescribed to treat advanced soft tissue sarcomas and advanced/metastatic renal cell carcinomas.

Dosage and Side Effects

  • Oral administration of Pazopanib tablet should occur at approximately the same time every day, without food (at least one hour prior to or two hours following a meal).
  • Tablets of pazopanib, either 400 mg or 200 mg, should be taken whole with water. It is not recommended to open, dissolve, break, or chew the capsules.
  • Pazopanib frequently causes nausea, vomiting, diarrhea, hypertension, rash, exhaustion, myelosuppression, taste changes, oedema, hair loss or discoloration, and changes in hair color.

Warning and Precautions

  • Fatal arterial thrombotic episodes have been reported in certain circumstances. Patients who have a higher risk of adverse problems should use pazopanib cautiously.
  • Patients who have experienced gastrointestinal bleeding or hemoptysis during the last six months are not encouraged to use Pazopanib 200 mg Tablet.
  • Prior to starting treatment and on a regular basis while receiving treatment, liver chemistries must be measured.
  • Individuals who are more likely to experience QT interval prolongation should use this drug with caution. It is advisable to think about monitoring electrocardiograms and electrolytes.
  • It is imperative that women who are capable of bearing children refrain from getting pregnant while taking Pazopanib.

FAQ's

What conditions does Pazopanib treat?

Pazopanib, containing pazopanib hydrochloride, is used to address advanced soft tissue sarcomas and advanced or metastatic renal cell carcinomas.

How should Pazopanib be taken?

Take Pazopanib tablet orally around the same time daily, without food, either one hour before or two hours after eating. Swallow the 200 mg or 400 mg tablets whole with water, avoiding opening, dissolving, breaking, or chewing them.

What are the common side effects of Pazopanib?

Common side effects include nausea, vomiting, diarrhea, hypertension, rash, fatigue, myelosuppression (like leucopenia, neutropenia, thrombocytopenia, and lymphopenia), taste changes, swelling, hair loss or color changes.

What are the warnings and precautions associated with Pazppanib?

Fatal arterial thrombotic episodes have occurred in certain cases. Patients at higher risk for adverse events should use Pazopanib cautiously. Individuals who’ve had gastrointestinal bleeding or hemoptysis in the last six months should avoid using it. Regular liver function tests are necessary during treatment.

Are there specific considerations for certain individuals taking Pazopanib?

Caution is advised for those at risk of QT interval prolongation. Electrocardiogram and electrolyte monitoring might be recommended. It’s crucial for women capable of pregnancy to avoid getting pregnant while on Pazopanib.

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