Sulfadiazine

  • Medicine- Salphaz 
  • API- Sulfadiazine
  •  Packaging- Tablets
  • Strength- 500 mg
  • Manufactured by- Jolly Healthcare
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Description

FDA-approved Sulfadiazine 500 mg tablets is an antibacterial drug that is commonly used to treat a variety of illnesses, such as meningitis and food poisoning.

Dosage and Side Effects

Adults typically take two to four grams (4 to 8 tablets) of sulfadiazine 500 mg at the beginning of treatment, then four grams (8 tablets) every day in divided doses for a maximum of seven days.

In children, sulfadiazine is typically started at 75 mg per kilogram of body weight and continued at 150 mg per kg of body weight per day in divided doses, up to a maximum of 6 grams per day.

Sulfadiazine tablets should always be taken with a full glass (8 ounces) of water, unless otherwise directed.To maintain healthy kidney function when taking pills, drink lots of fluids. It is not recommended to offer Sulfadiazine tablets to newborns.

Sulfadiazine most often reported side effects include nausea, vomiting, lack of appetite, and diarrhea.

Warning and Precautions

  • Administer Sulfadiazine tablets 500 mg cautiously in patients with impaired liver or kidney function, as well as those with severe allergies or bronchial asthma.

  • Avoid using sulfonamides for treating group A beta-hemolytic streptococcal infections. In established infections, they cannot eradicate the streptococcus, hence cannot prevent subsequent conditions like glomerulonephritis and rheumatic fever.

  • Maintain adequate fluid intake during sulfadiazine 500 mg tablet treatment to prevent crystalluria and the formation of stones.

  • Patients taking sulfadiazine pills should drink an eight-ounce glass of water with each dose and regularly throughout the day.

  • Frequent complete blood counts (CBC) and urinalysis with thorough microscopic examinations are necessary for patients receiving sulfonamides.

  • Individuals on sulfadiazine 500 mg treatment should immediately report symptoms such as sore throat, pallor, fever, purpura, or jaundice as these might indicate serious blood disorders at an early stage.

  • The use of sulfadiazine therapy is limited for nursing mothers due to the sulfonamides’ ability to cross the placenta and be excreted in breast milk, potentially leading to kernicterus.

FAQ's

What is use of Sulfadiazine? 

Sulfadiazine 500 mg Tablet is an FDA-approved antibacterial medication designed to prevent and treat specific bacterial infections, such as chancroid, urinary tract infections, Toxoplasma gondii encephalitis, and other related infections.

What are the available dosage strengths of Sulfadiazine?

Sulfadiazine is available in tablet form with a dosage strength of 500 mg.

Is sulfadiazine classified as a sulfonamide?

Yes, sulfadiazine tablets belong to the category of sulfonamide antibiotics.

How is Sulfadiazine typically administered?

Sulfadiazine is usually taken orally in tablet form.

What category of medication does Sulfadiazine belong to?

Sulfadiazine falls under the classification of Antibacterial (Sulfonamide) medications.