Etanercept 50mg, 25mg Injection

  • Medicine name- Etacept
  • API- Etanercept 
  • Pack Size- 1 ml PFS & 3 ml single-dose vial
  • Strength- 50mg, 25mg
  • Marketed by- Cipla Ltd
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Etanercept, a pharmaceutical compound, is utilized for treating various autoimmune conditions such as rheumatoid arthritis, juvenile idiopathic arthritis, and psoriatic arthritis. Its mechanism involves disrupting tumor necrosis factor (TNF), a fundamental element in autoimmune disorders often recognized as the “master regulator” of immune responses. Etanercept works by impeding TNF-alpha, effectively blocking the progression of autoimmune diseases.

This medication is applied in managing a spectrum of autoimmune disorders, including:

  • Juvenile rheumatoid arthritis
  • Moderate to severe rheumatoid arthritis
  • Psoriatic arthritis
  • Moderate-to-severe plaque psoriasis
  • Ankylosing Spondylitis

Dosage and Side Effects

Etanercept, available in a 50 mg dosage, is presented in vaccine form. The concentrations and strengths are detailed as follows:

  • A 50 mg single-use prefilled syringe contains 0.98 ml of a 50 mg per ml solution of etanercept.
  • A 50 mg Single-use Prefilled Autoinjector holds 0.98 mL of a 50 mg/mL solution of etanercept.
  • A 25 mg Single-use Prefilled Syringe contains 0.51 mL of a 50 mg/mL solution of etanercept.
  • A 25 mg Multiple-use vial contains 25 mg of etanercept.

The primary side effects of etanercept include infection and reactions at the injection site. Common adverse reactions to the 50 mg dose encompass mild nausea, headaches, stomach discomfort, injection site redness, vomiting, diarrhea, heartburn, cold symptoms, weakness, and changes in weight. However, certain adverse reactions associated with intacept 50 mg necessitate immediate medical attention, such as bleeding, bruising, breathing difficulties, numbness or tingling in extremities, signs of infections, chest pain, dizziness, blurred vision, joint pain, alterations in skin appearance, and coughing. When these reactions occur, it’s crucial for patients to promptly consult a doctor.

Warning and Precautions

  • Using etanercept 25 mg when an infection is active is not advised. When the infection is really serious, etanercept use should be discontinued or monitored closely by a physician.

  • In the event that a patient experiences systemic sickness while taking 25 mg of intacept, antifungal therapy should be considered.

  • There could be a fresh onset, aggravation, or demyelinating illness.

  • The patient’s risk of lymphoma is increased while taking this medicine.

  • There could be congestive heart failure.

  • When pancytopenia or aplastic anemia signs appear, it is best to stop using intacept 25 mg.

  • further testing for the hepatitis B carrier virus following many months of treatment.

  • There have been reports of severe allergic responses or hypersensitivity.

  • Autoimmune hepatitis or condition similar to lupus can occasionally happen.


How does Etanercept work in treating autoimmune diseases?

Etanercept functions by targeting and inhibiting tumor necrosis factor (TNF), a key player in the immune system’s inflammatory response. By blocking TNF, it helps regulate the immune system’s activity, reducing inflammation and managing autoimmune conditions.

What are the recommended storage conditions for Etanercept?

Etanercept typically needs refrigeration to maintain its stability. It’s advised to store it in the refrigerator between 36°F to 46°F (2°C to 8°C). Avoid freezing or exposing it to extreme temperatures.