Description
What Is The Generic Name Of Geftinat?
Generic name of Geftinat is Geftinib
Who Is The Manufacturer Of Geftinat (Geftinib)?
Geftinat is manufactured by Natco Pharma Limited, India.
Is Geftinat (Geftinib) 250mg Approved By USA FDA?
Yes, Geftinat (Geftinib) Is Approved By FDA. The Product Was Approved In 2003.
What Is The Dosage Of Geftinat (Geftinib) 250mg?
Geftinat is available as 250 mg orally once daily with or without food until disease progression or unacceptable toxicity.
What Are The Storage Conditions Of Geftinat (Geftinib) 250 Mg?
The product should be Stored at 20° to 25°C (68° to 77°F). Excursions are permitted between 15°C to 30°C (59°F to 86°F)
How Geftinat (Geftinib) 250 Mg Is Supplied?
Geftinat is supplied as pack of 30 tablets, each tablet of 250mg.
How Does Geftinat 250 Mg (Geftinib) Work?
The epidermal growth factor receptor (EGFR) is expressed on the cell surface of both normal and cancer cells and plays a role in the processes of cell growth and proliferation. Some EGFR activating mutations (exon 19 deletion or exon 21 point mutation L858R) within NSCLC cells have been identified as contributing to the promotion of tumor cell growth, blocking of apoptosis, increasing the production of angiogenic factors and facilitating the processes of metastasis. Gefitinib reversibly inhibits the kinase activity of wild-type and certain activating mutations of EGFR, preventing autophosphorylation of tyrosine residues associated with the receptor, thereby inhibiting further downstream signalling and blocking EGFR-dependent proliferation. Gefitinib binding affinity for EGFR exon 19 deletion or exon 21 point mutation L858R mutations is higher than its affinity for the wild-type EGFR. Gefitinib also inhibits IGF and PDGF-mediated signalling at clinically relevant concentrations; inhibition of other tyrosine kinase receptors has not been fully characterized.
What Is Geftinat 250 Mg (Geftinib) Used For?
Geftinib 250 mg is a tyrosine kinase inhibitor indicated for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) substitution mutations as detected by an FDA-approved test.
Is There Any Generic Or Bio Similar Available For Geftinat (Geftinib) 250 Mg.
Geftinat 250 mg (Geftinib) is a branded , affordable generic brand of Geftinib. There are other generic option available for Geftinib from reputed manufacturers.
What Is The Price Of Geftinat (Geftinib) 250 Mg In India?
You can call or WhatsApp +91-8130290915 or send mail to info@indiangenericmedicines.com to know the price.
Is It Safe To Buy Geftinat 250 Mg (Geftinib) In India From Local Distributor?
It is always better to check the credential of the person / distributor before confirming.
As per the legal guidelines, only patients can import the product after getting proper Documentation.
