Degarelix

Degarelix

Packaging- Single-Use Vial

Strength- 80mg/120mg

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Description

Degarelix is a GnRH receptor antagonist used for the treatment of patients with advanced prostate cancer.

Dosage and Side Effects

The recommended dose of Degarelix is for subcutaneous administration only and is not to be administered intravenously. Therapy is started with a dose of degarelix 240 mg given as two injections of 120 mg each. The starting dose is followed by the maintenance doses of 80 mg administered as a single injection every 28 days.

The most commonly reported degarelix side effects (≥10%) include injection site reactions (e.g., erythema, pain, swelling or induration), hot flashes, increased weight, and increases in serum levels of transaminases and gamma-glutamyltransferase (GGT).

Warning and Precautions

  • Use of degarelix 80 mg is restricted in patients with known hypersensitivity to degarelix or to any of the product components.
  • Patients with a known history of severe hypersensitivity reactions to degarelix should not be re-challenged with degarelix.
  • Women who are or may become pregnant should not take degarelix 240 mg treatment.
    Electrolyte abnormalities needs to be corrected. Consider the periodic monitoring of electrocardiograms and electrolytes.
  • The therapeutic effect of degarelix 80 mg should be assessed by measuring serum concentrations of prostate-specific antigen (PSA) periodically. In case PSA increases, the serum concentrations of testosterone should be measured.

FAQ's

What is Degarelix?

Degarelix is a hormonal therapy authorized for the treatment of prostate cancer. 

How should Degarelix be administered?

Degarelix comes as a powder for injection, which should be administered subcutaneously only. 

Is Degarelix injection the same as firmagon injection?

Degarelix injection is a hormone therapy drug and is also known by its brand name Firmagon. 

What dosage forms degarelix comes in?

It comes in two strengths, which are as follows:

  • Degarelix 80 mg
  • Degarelix 120 mg

How does Degarelix work?

Degarelix, a GnRH receptor antagonist binds reversibly to the pituitary GnRH receptors, thereby decreasing the release of gonadotropins and consequently testosterone.

Where can I buy Degarelix?

You can buy degarelix injection from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

The buyer should check the existing law in their home country before importing the product. 

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