Acalabrutinib 100 MG Capsules

  • Medicine Name- Acabrunat
  • API- Acalabrutinib
  • Packaging- 30 Capsules
  • Strength- 100mg
  • Manufactured by- Natco Pharma
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Description

Acalabrutinib, a highly selective, potent, Bruton tyrosine kinase (BTK) inhibitor is used for the treatment of patients with mantle cell lymphoma (MCL) (who have previously been treated with at least 1 therapy), and chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).

Dosage and Side Effects

The recommended dosage of acalabrutinib capsules as monotherapy for patients with MCL, CLL/ SLL is 100 mg administered orally with or without food approximately every 12 hours until disease progression or if unacceptable toxicity occurs. For patients with previously untreated CLL/SLL, the recommended dosage of Acalabrutinib in combination with the medicine obinutuzumab is 100 mg administered orally with or without food approximately every 12 hours until disease progression or in case of unacceptable toxicity. Swallow capsules whole with water without chewing, or crushing them.

In case a dose of Acalabrutinib is missed by an excess of 3 hours, skip it and take the very next dose at its regularly scheduled time. Additional capsules should not be taken in order to make up for a missed dose.

The most common side effects of Acalabrutinib are upper respiratory tract infection, musculoskeletal pain, neutropenia, anemia, thrombocytopenia, headache, and diarrhea.

Warning and Precautions

  • Critical and serious infections, including opportunistic infections, may occur in individuals with hematologic malignancies treated with Acalabrutinib. Consider prophylaxis in patients who are at higher risk for opportunistic infections. Monitor patients for signs and symptoms of infection and treat them promptly.

  • Fatal and severe hemorrhagic events may occur in those with hematologic malignancies treated with Acalabrutinib. Use of antithrombotic agents concomitantly with Acalabrutinib may further increase the probability of hemorrhage. Monitor patients for probable signs of bleeding.

  • Grade 3/4 cytopenias, including anemia, neutropenia, thrombocytopenia, and lymphopenia, may develop in those with hematologic malignancies treated with Acabrunat 100 mg. Monitor complete blood counts (CBC) regularly during therapy. Interrupt therapy, scale down the dose, or discontinue therapy as warranted.

  • Second primary malignancies (SPM), including skin cancers and certain other solid tumors, may be established in those exposed to Acalabrutinib. Skin cancer is the most frequently occurring second primary malignancy. Monitor patients for signs and symptoms of skin cancers and advise protection from sun exposure.

  • Grade 3 atrial fibrillation or flutter may develop in patients treated with Acabrunat capsules. The risk may be higher in patients with cardiac risk factors, previous arrhythmias, hypertension, and acute infection. Monitor for symptoms of arrhythmia (such as dizziness, palpitations, syncope, or dyspnea) and manage as appropriate.

FAQ's

What is Acabrunat?

Acabrunat is a generic of Calquence that contains Acalabrutinib as the main component. It is used for the treatment of mantle cell lymphoma (MCL), and chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).

Who has launched the generic Acabrunat?

Natco Pharma Limited has launched the generic Acabrunat, as 100 mg capsules for oral administration.

How do I take Acalabrutinib

Take Acalabrutinib 2 times daily (about 12 hours apart). Take it with or without food. Swallow whole with a glass of water.

How should I store Acalabrutinib?

Store it at 20-25°C (68-77°F); excursions permitted to 15-30°C (59-86°F). Store in a closed container away from heat, light, and moisture.

How much does Acalabrutinib cost in India?

Acalabrutinib 100 mg cost in India is very reasonable and can vary. To procure it legally, you can call us at (+91) 8130290915, TOLL-FREE: 1800-889-1064, Or Write us at info@indiangenericmedicines.com.

Can Acalabrutinib be used while I’m pregnant?

Acalabrutinib capsules may cause fetal harm when administered to a pregnant woman. Discuss with your doctor about the best way to control your disease during pregnancy. 

Can Acalabrutinib be used while breastfeeding?

Lactating women should not breastfeed while taking Acalabrutinib and for two weeks after the last dose. Discuss with your doctor if you are breastfeeding or intend to breastfeed.

Where can I get Acalabrutinib at the best price? 

Order Acalabrutinib at the best price today. We request you to Call/WhatsApp us at (+91) 8130290915 or dial our TOLL-FREE: 1800-889-1064 or Write us at info@indiangenericmedicines.com. We are committed to providing you with the best Acalabrutinib 100 mg price from India. That is why we’ll match the cost or price of any suppliers/distributors/facilitators in the market who require a medical prescription.

Is Acalabrutinib (Acabrunat) available in India?

Acabrunat is a (prescription drug, doctor-prescribed medication, or health care professional-prescribed medicine) pharmaceutical drug that can be legally dispensed against a medical prescription. Acabrunat can be made available through the network of authorized distributors in India (Bangalore, Ahmedabad, Kolkata, Chennai, Mumbai, Delhi, Hyderabad, Pune, etc.)

Can You Send the Acalabrutinib to Foreign Destinations?

Buy generic Acalabrutinib online at the best price from a leading supplier. Indian Generic Medicines can assist in the delivery of Acalabrutinib; the doctor-prescribed medicine to the UK, Hong Kong, UAE, South Africa, Canada, Australia, Philippines, the USA, Saudi Arabia, Thailand, China, Kazakhstan, Sri Lanka, Zambia, Uzbekistan, Pakistan, Kuwait, Sweden, Malaysia, Turkey, Afghanistan, Singapore, Nepal, Qatar, Japan, and many other countries.

What is the procedure to buy Acalabrutinib from Indian Generic Medicines

Patients can fill out the order form or send mail to info@indiangenericmedicines.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008891064. We will reply ASAP with the details of the Acalabrutinib 100 mg price and the procurement procedure.

Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy acalabrutinib (Acabrunat) online from India?

Yes, one can buy acalabrutinib (Acabrunat) online from India-based Indian Generic Medicines if it is not (yet) registered or is unavailable in their respective country. We can help facilitate the supply/export of Acabrunat capsules through legal channels.