Description
Indication
Sorafenib is a kinase inhibitor indicated for the treatment of
- Unresectable hepatocellular carcinoma
- Advanced renal cell carcinoma
Dosage
400 mg (2 tablets) orally twice daily without food.
- Treatment interruption and/or dose reduction may be needed to manage suspected adverse drug reactions. Dose may be reduced to 400 mg once daily or to 400 mg every other day.
Mechanism Of Action
Sorafenib is a kinase inhibitor that decreases tumor cell proliferation in vitro. Sorafenib was shown to inhibit multiple intracellular (CRAF, BRAF and mutant BRAF) and cell surface kinases (KIT, FLT-3, RET, VEGFR-1, VEGFR-2, VEGFR-3, and PDGFR-ß). Several of these kinases are thought to be involved in tumor cell signaling, angiogenesis, and apoptosis. Sorafenib inhibited tumor growth and angiogenesis of human hepatocellular carcinoma and renal cell carcinoma, and several other human tumor xenografts in immunocompromised mice.
Side Effect
- Abdominal or stomach pain
- Bleeding gums
- Bloating of the abdomen or stomach
- Blood in the urine or stools
- Blurred vision
- Clay-colored stools
- Coughing up blood
- Dark urine
- Difficulty with breathing or swallowing
What is the generic name of Soranib 200mg tablets?
Generic name of Soranib is Sorafenib
Who is the manufacturer of Soranib 200mg tablets?
Soranib is manufactured and marketed by Cipla Ltd.
Is Soranib approved by USA FDA?
Yes, Soranib is approved by FDA. The product was approved in 2005.
How Soranib is supplied?
Soranib is available as 120 tablets of 200mg each.
What are the storage conditions of Soranib 200mg tablets?
Store at 20o C to 25°C (68o F to 77°F). Store in the original package.
How does Soranib 200mg tablets work?
Sorafenib is a kinase inhibitor that decreases tumor cell proliferation in vitro. Sorafenib was shown to inhibit multiple intracellular (CRAF, BRAF and mutant BRAF) and cell surface kinases (KIT, FLT-3, RET, VEGFR-1, VEGFR-2, VEGFR-3, and PDGFR-ß). Several of these kinases are thought to be involved in tumor cell signaling, angiogenesis, and apoptosis. Sorafenib inhibited tumor growth and angiogenesis of human hepatocellular carcinoma and renal cell carcinoma, and several other human tumor xenografts in immunocompromised mice.
What is Soranib 200mg tablets used for?
Soranib is indicated for the treatment of patients with unresectable hepatocellular carcinoma (HCC). Renal Cell Carcinoma and for the treatment of patients with advanced renal cell carcinoma (RCC).
How many brands of Soranib 200mg tablets are available in India?
Soranib is branded generic medicine. There are other generics available in India.
Is there any generic or bio similar available for Soranib 200mg tablets.
There are generics of Soranib available in India.
What is the price of Soranib 200mg tablets in India?
You can call or WhatsApp +91- 8130290915 or send mail to info@indiangenericmedicines.com to know the price.
Is it safe to buy Soranib 200mg tablets in India from local distributor?
It is always better to check the credential of the person / distributor before confirming.
As per the legal guidelines, only patients can import the product after getting proper Documentation.
