Edaravone 1.5mg Injection is indicated for the treatment of amyotrophic lateral sclerosis (ALS).
It is a white crystalline powder with inactive ingredients L-cysteine hydrochloride hydrate, polyvinyl alcohol, simethicone emulsion, sodium bisulfite, sorbitol, and xanthan gum.
Edaravone: The recommended dosage is 60 mg administered as an intravenous infusion  over 60 minutes.Â
Most common adverse reactions (at least 10% of patients treated with Edaravone and greater than placebo) are contusion, gait disturbance, and headache.
Hypersensitivity Reactions: Advise patients to seek immediate medical care.Â
Sulfite Allergic Reactions: Edaravone contains sodium bisulfite, which may cause allergic type reactions, including anaphylactic symptoms and asthmatic episodes in susceptible people.
What is edaravone used for?
Edaravone is indicated for the treatment of amyotrophic lateral sclerosis (ALS).
What is the mechanism of action of edaravone?
The mechanism by which Edaravone exerts its therapeutic effect in patients with ALS is unknown.Â
Is edaravone an antioxidant?
Edaravone is a low-molecular-weight antioxidant drug targeting peroxyl radicals among many types of reactive oxygen species. Because of its amphiphilicity, it scavenges both lipid- and water-soluble peroxyl radicals by donating an electron to the radical.
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