Methylprednisolone tablets

  • Medicine name- Dispred
  • API- Methylprednisolone
  • Pack Size- strips of 10 tablets
  • Strength- 8 mg and 4 mg
  • Marketed By: J B Chemicals and Pharmaceuticals Ltd
Get an Enquiry


Methylprednisolone Tablet is a synthetic glucocorticoid, primarily used for its anti-inflammatory and immunosuppressive effects. Its different uses are as follows:

  • Endocrine Disorders | Rheumatic Disorders | Collagen Diseases | Dermatologic Diseases
  • Allergic States | Ophthalmic Diseases | Gastrointestinal Diseases | Respiratory Diseases
  • Hematologic Disorders | Neoplastic Diseases | Edematous States |Nervous System: Acute exacerbations of multiple sclerosis

Dosage and Side Effects

The initial dosage of Methylprednisolone Tablets may vary from 4 mg to 48 mg daily on behalf of the specific disease entity being treated. In circumstances of less severity lower doses will generally suffice while in selected patients higher initial doses may be needed. The initial dosage needs to be maintained or adjusted until a satisfactory response is noted. If after a reasonable time-span there is a lack of satisfactory clinical response, Methylprednisolone therapy should be interrupted and the patient transferred to other appropriate therapy.

The most commonly reported side effects due to methylprednisolone tablets may include: trouble sleeping, appetite changes, vomiting, heartburn, headache, dizziness, increased sweating, nausea, or acne.

Warning and Precautions

  • Kaposi’s sarcoma has been noted to emerge in patients taking treatment with corticosteroid therapy. Interruption of corticosteroids therapy may result in clinical remission.

  • Pheochromocytoma crisis, which can be fatal, has been noted following administration of systemic corticosteroids, including methylprednisolone 8 mg or any other dosage strengths. Corticosteroids should only be used in patients with suspected or identified pheochromocytoma after an apt risk or benefit evaluation.

  • Thrombosis including venous thromboembolism has been noted to emerge with corticosteroids. As a result corticosteroid therapy should be used with precise caution in patients who have or may be predisposed to thromboembolic disorders.

  • As sodium retention with resultant edema and potassium loss may occur in patients receiving corticosteroids, these agents need to be used with precise caution in patients with congestive heart failure (use only in case strictly necessary), hypertension, or renal insufficiency.

  • Because glucocorticoids may be responsible for producing or aggravating Cushing’s syndrome, glucocorticoids including (methylprednisolone 32 mg or any other dosage strengths) needs to be avoided in patients with Cushing’s disease.

  • Allergic reactions (angioedema) may emerge. Because rare instances of skin reactions and anaphylactic/anaphylactoid reactions have emerged in patients with methylprednisolone therapy, apt precautionary measures need to be considered prior to use, especially when the patient has a known history of allergy to any medicine.

  • Caution is needed in patients with systemic sclerosis because an increased incidence of scleroderma renal crisis has been noticed with methylprednisolone. Treatment with methylprednisolone 16 mg or with any other dosage strengths needs to be used with precise caution in patients with renal insufficiency.

  • Use of live or live, attenuated vaccines is restricted in patients receiving treatment with immunosuppressive doses of Methylprednisolone. While on Methylprednisolone therapy patients should not be vaccinated against smallpox.


What is Methylprednisolone?

Methylprednisolone is a corticosteroid, anti-inflammatory agent, authorized to treat to inflammatory conditions such as arthritis, ulcerative colitis, lupus, psoriasis, allergic disorders, endocrine disorders, and conditions that affect the eyes, skin, lungs, stomach nervous system or blood cells. It may be used alone or along with other medicines.

What strengths of methylprednisolone tablets are available? 

Tablets are available in different dosage strengths which are as

  • Methylprednisolone 2 mg
  • Methylprednisolone 4 mg
  • Methylprednisolone 8 mg
  • Methylprednisolone 16 mg
  • Methylprednisolone 32 mg

What type of drug is Methylprednisolone?

Methylprednisolone specifically is a type of drug called Corticosteroids.

How is Methylprednisolone administered? 

Methylprednisolone is supplied in the form of tablets for oral administration. 

How to take Methylprednisolone Tablets? 

Take the prescribed dosage of methylprednisolone with food. Swallow the methylprednisolone tablet with a drink of water.