Azacitidine is a nucleoside metabolic inhibitor used for continued treatment of adult patients with acute myeloid leukemia (AML) who achieved first complete remission (CR) or complete remission with incomplete blood count recovery (CRi) following intensive induction chemotherapy and can not complete the intensive curative therapy.
The recommended dosage of azacitidine tablet is 300 mg orally once daily with or without food on Days 1’st through 14’th of each 28-day cycle. Continue treatment until the disease is progressive or unacceptable toxicity occurs.
Do not crush, split, or chew the tablets of Azacitidine. Take a dose persistently each day. If a dose is missed, or not taken at the usual scheduled time, take the dose as promptly as possible on the same day, and resume the normal schedule the following day. Avoid taking a couple doses on the very same day. In case a dose is vomited, do not take another dose on the very same day. Resume the general schedule the following day.
Administer an antiemetic 30 minutes before each dose of Azacitidine for the first 2 cycles. Antiemetic prophylaxis may be omitted after 2 cycles in case there has been no vomiting and nausea.
Note: Do not substitute azacitidine tablets for intravenous or subcutaneous azacitidine. The indications and dosing regimen for this medicine differ from that of intravenous or subcutaneous azacitidine.
The most commonly reported side effects due to Azacitidine may include: decreased appetite, nausea, vomiting, diarrhea, fatigue/asthenia, febrile neutropenia, constipation, pneumonia, abdominal pain, arthralgia, dizziness, and pain in extremity.
What is Azacitidine?
Azacitidine oral is authorized for the treatment of acute myeloid leukemia (AML) in thise who are in remission but cannot complete other treatments for this condition.
What dosage strengths Azacitidine Tablet is supplied?
This medicinal product is supplied in following dosage strengths, which are as follows:
How is Azacitidine administered?
Azacitidine comes as tablets and to be administered by (mouth) orally. It is typically taken with or without meals once daily.
What are the different forms of Azacitidine?
It comes in two different forms:
Azacitidine Injection and Tablet
What type of medicine is Azacitidine?
Azacitidine specifically is a type of medicine known as demethylation agents.
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