Azacitidine Tablets 200MG & 300MG tablets

  • Medicine Name- Xpreza 
  • API- Azacitidine
  • Packaging- 14 Tablets
  • Strength- 200 mg/300 mg
  • Manufactured by- Natco Pharma
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Description

Oral Azacitidine, supplied under the generic brand Xpreza 200, is a nucleoside metabolic inhibitor used for continued treatment of certain adults with acute myeloid leukemia (AML) who had a first complete remission (CR) or complete remission with incomplete blood count recovery (CRi) following intensive induction chemotherapy and are not able to complete intensive curative therapy.

Dosage and Side Effects

The recommended dosage of azacitidine tablet is 300 mg orally once daily with or without food on Days 1 through 14 of each 28-day cycle. Continue treatment until the disease is progressive or unacceptable toxicity occurs.

Do not crush, split, or chew the tablets of Azacitidine. Take a dose persistently each day. If a dose is missed, or not taken at the usual scheduled time, take the dose as promptly as possible on the same day, and resume the normal schedule the following day. Avoid taking a couple of doses on the very same day. In case a dose is vomited, do not take another dose on the very same day. Resume the general schedule the following day.

Administer an antiemetic 30 minutes before each dose of Azacitidine for the first 2 cycles. Antiemetic prophylaxis may be omitted after 2 cycles in case there has been no vomiting and nausea.

Note: Do not substitute azacitidine tablets for intravenous or subcutaneous azacitidine. The indications and dosing regimen for this medicine differ from that of intravenous or subcutaneous azacitidine.

The most common side effects of oral Azacitidine are constipation, vomiting, diarrhea, fatigue/asthenia, nausea, pneumonia, abdominal pain, febrile neutropenia, arthralgia, decreased appetite, dizziness, and pain in extremity.

Warning and Precautions

  • Because of substantial differences in the pharmacokinetic parameters, the standard dose and schedule for azacitidine are different from those for intravenous (IV) or subcutaneous (SC) azacitidine products. Do not substitute azacitidine 200 mg/300 mg pills for intravenous or subcutaneous azacitidine.

  • New or worsening Grade 3/4 thrombocytopenia and neutropenia may occur in those who received azacitidine 200 mg/300 mg tablet. Assess complete blood counts and modify the dosage as required. Standard supportive care must be provided, including hematopoietic growth factors, in case myelosuppression emerges.

  • The safety and effectiveness of azacitidine tablets for the treatment of myelodysplastic syndromes (MDS) have not been established. Treatment of patients with myelodysplastic syndromes (MDS) with oral azacitidine is not recommended.

  • Mechanism of action and findings suggest that azacitidine 300 mg/200 mg can cause fetal harm if administered to a pregnant woman. Females of reproductive age/potential should use effective contraception during treatment and for at least 6 months after the final dose.

FAQ's

What is Xpreza?

Xpreza 200/300 is a generic of Onureg that contains Azacitidine as the main component. This medicine is used for the treatment of patients with acute myeloid leukemia (AML). 

Who has launched the generic Xpreza 200/300?

Natco Pharma Ltd has launched the generic Xpreza, as 200 mg/300 mg tablets for oral administration.

What dosage strengths of oral Azacitidine supplied?

Oral azacitidine is supplied as 200 mg or 300 mg film-coated tablets for oral administration/use.

How do I store Azacitidine?

Store bottles at 20-25°C (68-77°F); excursions permitted between 15-30°C (59-86°F). Keep the bottle well closed. Store and dispense in the original bottle (with two desiccant canisters). 

How much does Azacitidine cost in India?

Azacitidine 200 mg/300 mg cost in India is very reasonable and can vary. To procure it legally, you can call us at (+91) 8130290915, TOLL-FREE: 1800-889-1064, Or Write us at info@indiangenericmedicines.com.

Where can I get Azacitidine at the best Price? 

Order azacitidine mg at the best price today. We request you to Call/WhatsApp us at (+91) 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 or Write us at info@indiangenericmedicines.com. We’re fully committed to providing you with the best Azacitidine price from India. That is why we’ll match the cost/price of any other existing suppliers/distributors in the market who require a medical prescription.

Is Azacitidine available in India?

Azacitidine is a (prescription drug, doctor-prescribed medication, or health care professional-prescribed medicine) pharmaceutical drug that can be legally dispensed against a medical prescription. Azacitidine can be made available through the network of authorized distributors in India. (Ahmedabad, Hyderabad, Kolkata, Mumbai, Bangalore, Chennai, Delhi, Pune, etc.)

Can You Send the Azacitidine to Foreign Destinations?

Buy generic Azacitidine online at the best/lowest price from a leading supplier. Indian Generic Medicines can assist in the delivery of Azacitidine; the doctor-prescribed medication to the UK, Canada, Australia, Thailand, China, South Africa, Kazakhstan, Uzbekistan, Zambia, Philippines, the USA, Saudi Arabia, UAE, Pakistan, Kuwait, Sri Lanka, Sweden, Hong Kong, Turkey, Afghanistan, Malaysia, Singapore, Qatar, Japan, Nepal, and many other countries.

What is the procedure for buying Azacitidine from Indian Generic Medicines

Patients can fill out the order form or send mail to info@indiangenericmedicines.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008891064. We will reply ASAP with the details of the Azacitidine 200 mg/300 mg price and the procurement procedure.

Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy Azacitidine online from India?

Yes, one can buy Azacitidine 200 mg/300 mg online from India-based Indian Generic Medicines if it is not (yet) registered or is unavailable in their respective country. We can help facilitate the supply/export of generic Azacitidine through legal channels.