Nintedanib Capsules 100 MG/150 MG

  • Medicine Name- Cyendiv
  • API- Nintedanib
  • Packaging- 60 Capsules
  • Strength- 100 mg/150 mg
  • Manufactured by- Boehringer Ingelheim
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Description

Nintedanib is a small molecule tyrosine kinase inhibitor that binds to a family of growth factor receptors and helps prevent the proliferation of fibroblasts. It reduces the current fibrotic procedure and resists the progression to chronic damage. Nintedanib is a tyrosine kinase inhibitor used for the treatment and management of idiopathic pulmonary fibrosis (IPF), systemic sclerosis-associated interstitial lung disease (ILD), and interstitial lung disease (ILD) with progressive phenotype.

Dosage and Side Effects

The typical recommended dosage is 150 mg twice daily administered with food and fluids. Capsules can be swallowed whole. Crushing, chewing, or splitting the capsules may cause a bitter taste. In cases of mild hepatic impairment (Child-Pugh class A), low body mass index (BMI), or persistent gastrointestinal side effects, a dose reduction to 100 mg twice daily is recommended.

If a dose is missed or skipped, the advice is to continue the routine schedule. It is not advisable to take additional capsules to catch/make up for the missed dose.

The most common side effects of Nintedanib are decreased appetite, nausea, diarrhea, abdominal pain, weight decrease, vomiting, liver enzyme elevation, headache, and hypertension.

Warning and Precautions

  • Treatment with Nintedanib is not recommended in those with moderate (Child Pugh B) or critical (Child-Pugh C) hepatic impairment. Individuals with mild hepatic impairment (Child-Pugh A) can be treated with a reduced dose of Nintedanib.

  • Cases of drug-induced liver injury (DILI) may occur with Nintedanib 100 mg/150 mg treatment. Conduct liver function tests (AST, ALT, and bilirubin) before initiating this treatment, at regular intervals throughout the initial three months of this therapy, and periodically thereafter.

  • Measure liver tests promptly in individuals who report symptoms that may indicate liver injury, including anorexia, fatigue, right upper abdominal discomfort, dark urine, or jaundice. Dosage can be modified or interrupted for liver enzyme elevations.

  • Cyendiv may elevate the risk of bleeding. Non-serious and serious bleeding events, some fatal, may occur. Use this medication in patients with a previous risk of bleeding only if the anticipated benefit outweighs the potential risk.

  • Nintedanib may boost the probability of gastrointestinal perforation. Use caution when treating individuals who have had recent abdominal surgery, known history of diverticular disease, or taking concomitant corticosteroids or NSAIDs. Discontinue this treatment in those who develop gastrointestinal perforation. Only use it in those with a known risk of gastrointestinal perforation if the anticipated benefit outweighs the potential risk.

FAQ's

What is Cyendiv?

Cyendiv is a generic of Ofev which contains Nintedanib as the main component. This therapeutic drug is used for the treatment of idiopathic pulmonary fibrosis (IPF) and certain interstitial lung diseases (ILDs).

Who has launched the generic Cyendiv?

Boehringer Ingelheim has launched the generic Cyendiv, in 100 mg and 150 mg capsules for oral use.

How do I take Nintedanib

Nintedanib is available in soft capsules with 150 mg and 100 mg dosages. Take capsules completely with food and fluids. Crushing, chewing, or splitting the capsules can be responsible for causing a bitter taste. 

How do I store Nintedanib?

Store the capsules at 25°C (77°F); excursions permitted to 15-30°C (59-86°F). Protect the medicine from exposure to high humidity and avoid excessive heat.

How much does Nintedanib cost in India?

Nintedanib 100 mg/150 mg cost in India is reasonable and can vary. To procure it legally, you can call us at (+91) 8130290915, TOLL-FREE: 1800-889-1064, Or Write us at info@indiangenericmedicines.com.

Can Nintedanib be used while I’m pregnant?

Nintedanib Capsules may be unsafe if used during pregnancy. Contact your provider about the best way to help control your disease during pregnancy. 

Can Nintedanib be used while breastfeeding?

Breastfeeding is not recommended while on Nintedanib. Contact your provider if you are breastfeeding or intend to breastfeed.

Where can I get Nintedanib at the best Price? 

Order Nintedanib at the best price today. We request you to Call/WhatsApp us at (+91) 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 or Write us at info@indiangenericmedicines.com. We are fully committed to providing you with the best Nintedanib price from India. That is why we’ll match the cost/price of any other existing suppliers/distributors in the market who require a medical prescription.

Is Nintedanib available in India?

Nintedanib is a (prescription drug, doctor-prescribed medication, or health care professional-prescribed medicine) pharmaceutical drug that can be legally dispensed against a medical prescription. Nintedanib can be made available through the network of authorized distributors in India. (Mumbai, Ahmedabad, Kolkata, Hyderabad, Bangalore, Chennai, Delhi, Pune, etc.)

Can You Send the Nintedanib to Foreign Destinations?

Buy generic Nintedanib online at the best/lowest price from a leading supplier. Indian Generic Medicines can assist in the delivery of Nintedanib; the doctor-prescribed medication to the UK, Canada, Australia, Philippines, the USA, Saudi Arabia, Thailand, China, South Africa, Kazakhstan, Uzbekistan, Zambia, Hong Kong, Pakistan, Kuwait, Sri Lanka, Sweden, UAE, Turkey, Afghanistan, Malaysia, Singapore, Qatar, Japan, Nepal, and many other countries.

What is the procedure to buy Nintedanib from Indian Generic Medicines

Patients can fill out the order form or send mail to info@indiangenericmedicines.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008891064. We will reply ASAP with the details of the Nintedanib 100 mg/150 mg price and the procurement procedure.

Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy Nintedanib online from India?

Yes, one can buy Nintedanib 100 mg/150 mg online from India-based Indian Generic Medicines if it is not (yet) registered or is unavailable in their respective country. We can facilitate the supply/export of generic Nintedanib capsules through legal channels.