Romiplostim 250 mcg Injection

  • Medicine Name: Romiset
  • API- Romiplostim
  • Packaging-  single dose vial
  • Strength- 250 mcg
  • Manufactured by- Alkem Laboratories Ltd
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helps increase platelet counts in chronic immune thrombocytopenia (ITP) patients who haven’t responded well to other treatments like corticosteroids or splenectomy.

Important Points:

  • Not for other causes of low platelets or myelodysplastic syndrome (MDS).
  • Use only for ITP patients at risk of bleeding, not to reach normal platelet levels.

Dosage and Side Effects

  • Start with a weekly subcutaneous injection of 1 mcg/kg.
  • Adjust doses to maintain platelets above 50 x 10^9/L but not over 400 x 10^9/L.
  • Stop if platelet count doesn’t improve after 4 weeks at the highest dose.
  • Dispose of any unused portions in the vial.

Common side effects of Romiplostim 250 mcg include joint pain, dizziness, trouble sleeping, muscle pain, abdominal discomfort, and tingling sensations.

Warning and Precautions

  • Raises blast cell counts and risks leukemia in certain blood disorders.
  • Be careful about blood clotting, especially in ITP patients with liver issues.
  • Monitor blood counts after stopping Romiplostim to watch for worsening platelet levels.


What is Romiplostim?

Romiplostim is a medication used to increase platelet counts in people with chronic immune thrombocytopenia (ITP), a condition where the body’s immune system attacks its platelets.

 How does Romiplostim work?

It stimulates the production of platelets in the bone marrow, helping to raise platelet levels and reduce the risk of bleeding in individuals with chronic ITP.

Who can use Romiplostim?

Romiplostim injection is prescribed for adults and sometimes for children (under specific conditions) who have chronic ITP and haven’t responded well to other treatments like steroids or splenectomy.

 How is Romiplostim administered?

It’s given as a subcutaneous (under the skin) injection, usually once a week. The dosage is determined based on body weight and adjusted to maintain safe platelet levels.