Dulaglutide

  • Brand Name: Trulicity
  • API: Dulaglutide
  • Packaging: Single-dose Pre-Filled Pen
  • Strength: 1.5 mg/0.5 mL
  • Manufacturer: Eli Lilly and Company
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Description

Trulicity (Dulaglutide 1.5 MG/0.5 mL Pre-Filled Pen)

Uses of Medicine: Trulicity (Dulaglutide 1.5 MG/0.5 mL Pre-Filled Pen) is an anti-diabetic medicine used primarily to manage type 2 diabetes (T2D) in adults and pediatric patients aged 10 years and older. It works by mimicking the action of a natural hormone called GLP-1, which helps to lower blood sugar levels by stimulating insulin secretion and reducing the amount of glucose produced by the liver. Trulicity solution for injection is also effective in reducing the risk of major cardiovascular events, making it a valuable option for patients with heart disease. This once-weekly injection is convenient and helps improve glycemic control, promoting better long-term health outcomes for individuals with type 2 diabetes (T2D).

Dosage and Side Effects

Adult Dosage: Starting with a 0.75 mg dosage injected subcutaneously once weekly, patients can effectively begin their journey toward better glycemic control. After assessing the body’s response, the dosage can be increased to 1.5 mg once weekly for enhanced glycemic management. For those requiring further improvement in blood sugar levels, a gradual increment of 1.5 mg after at least four weeks on the current dosage is recommended. It’s crucial to note that the maximum dosage should not exceed 4.5 mg injected subcutaneously once weekly to maintain safety and efficacy.

Pediatric Dosage: When considering pediatric dosage guidelines for glycemic control, it is essential to begin with a recommended starting dosage of 0.75 mg, administered subcutaneously once weekly. This starting dose provides a foundation for managing blood glucose levels effectively. However, if additional glycemic control is required, the dosage can be carefully increased to a maximum recommended dosage of 1.5 mg once weekly. It is crucial to maintain the initial 0.75 mg dosage for at least 4 weeks before making any adjustments, ensuring that the child’s response is adequately monitored.

The most commonly reported side effects of Dulaglutide 1.5 mg/0.5 mL solution for injection are nausea, abdominal pain, diarrhea, vomiting, and decreased appetite.

Warning and Precautions

  • Treatment with Trulicity may increase the risk of thyroid C-cell tumors, including medullary thyroid carcinoma (MTC). Patients with a family history of MTC or multiple endocrine neoplasia syndrome type 2 (MEN 2) should avoid this medication. Regular monitoring of thyroid function is recommended to mitigate potential risks. Consult healthcare professionals for guidance.
  • Acute pancreatitis has been observed in patients treated with Dulaglutide. It is essential to monitor patients for signs and symptoms of pancreatitis, such as severe abdominal pain that may radiate to the back. Discontinuation of treatment should be considered if pancreatitis is suspected. This medicine should not be restarted unless an alternative etiology for pancreatitis is identified.
  • When used in combination with insulin or insulin secretagogues, Dulaglutide 1.5 mg/0.5 mL solution for injections may increase the risk of hypoglycemia. Regular blood glucose monitoring is recommended, and dosage adjustments for insulin or insulin secretagogues may be necessary to reduce the risk of hypoglycemia. Educating patients about recognizing the symptoms of hypoglycemia is essential.
  • Serious hypersensitivity reactions, including anaphylaxis, angioedema, and urticaria, have been reported. If a hypersensitivity reaction occurs, treatment should be discontinued immediately. Patients with a history of hypersensitivity reactions to GLP-1 receptor agonists should be cautious when considering this therapeutic drug.
  • Dulaglutide has been associated with acute kidney injury, sometimes requiring dialysis. Patients with a history of renal impairment or dehydration are at higher risk. Monitoring renal function is advised, especially during the initiation of treatment or dosage increases. Promptly address any signs of kidney injury to prevent severe complications.
  • This therapeutic drug is not recommended for use in patients with severe gastrointestinal disease, including gastroparesis. The medication slows gastric emptying, which can exacerbate symptoms of gastrointestinal disorders. Patients with a history of gastrointestinal issues should be closely monitored if treatment is considered.
  • Rapid improvement in glycemic control has been linked to temporary worsening of diabetic retinopathy. Trulicity 1.5 mg/0.5 mL pen users should have regular ophthalmologic assessments to manage any potential complications related to diabetic retinopathy.
  • Treatment with this drug may increase the risk of gallbladder disease, including cholecystitis. Patients should be monitored for signs and symptoms of gallbladder disease, such as abdominal pain and jaundice, and treatment should be adjusted as necessary.
  • The use of Trulicity pen during pregnancy is not recommended unless the potential benefits outweigh the risks to the fetus. Pregnant women should be advised to discuss alternative treatments with their healthcare providers to avoid potential harm to the developing fetus.

FAQ's

What is Trulicity?

Trulicity is a once-weekly injectable medication containing Dulaglutide as the active pharmaceutical ingredient (API). It’s available in 1.5 mg/0.5 mL pre-filled pens and is primarily used for managing type 2 diabetes. Trulicity helps control blood sugar levels, reducing the risk of heart disease in diabetic patients.

How is Dulaglutide 1.5 mg/0.5 mL pen administered?

Dulaglutide 1.5 mg/0.5 mL pen, a GLP-1 receptor agonist is administered once weekly via a prefilled injection pen, offering a convenient solution for diabetes management.

How should I store Dulaglutide 1.5 mg/0.5 mL pen?

Store the Dulaglutide pen in the refrigerator at 36°F to 46°F (2°C to 8°C). Avoid freezing. If needed, it can be stored at room temperature (below 86°F or 30°C) for up to 14 days.

How much does Trulicity (dulaglutide) pen cost in India?

Trulicity (dulaglutide) pen is available in India at competitive and reasonable prices, though the cost may vary depending on the supplier and location. For those looking to buy Dulaglutide online legally and without hassle, Indian Generic Medicines (IGM) offers an easy and reliable solution. To inquire about the current Trulicity (dulaglutide) pen price in India, simply call us at +91 8130290915 or dial our TOLL-FREE Number 1800-889-1064. You can also email us at info@indiangenericmedicines.com for detailed pricing information and assistance.

Where can I get Trulicity (dulaglutide) pens at the best price?

To ensure you receive Dulaglutide at the most competitive price, reach out to Indian Generic Medicines (IGM) today. We are committed to offering the best prices for Dulaglutide from India, and we can match or beat the cost offered by other suppliers or distributors in the market. Contact us via Call/WhatsApp at +91 8130290915, or use our TOLL-FREE number 1800-889-1064. Alternatively, you can email us at info@indiangenericmedicines.com. Please note that a valid medical prescription is required to purchase Dulaglutide.

Is Trulicity (dulaglutide) pens available in India?

Yes, Trulicity (dulaglutide) pen is available in India as a prescription medicine. This pharmaceutical drug can be legally obtained through India’s authorized distributor network, which spans major cities such as Hyderabad, Mumbai, Bangalore, Ahmedabad, Delhi, Kolkata, Chennai, and Pune. To buy Trulicity (dulaglutide) pens online from India, a valid prescription from a healthcare professional is required. Indian Generic Medicines (IGM) can assist you in sourcing Dulaglutide from India’s top suppliers.

Can you send Trulicity (dulaglutide pen) to foreign destinations?

Indian Generic Medicines (IGM) specializes in the export and delivery of generic Dulaglutide 1.5 mg/0.5 mL pen at the lowest prices. We facilitate the shipment of Dulaglutide 1.5 mg/0.5 mL pen to various countries, including but not limited to UAE, Australia, the USA, Saudi Arabia, Canada, the UK, Brazil, and South Africa. Whether you are located in Australia, North America, South America, Eastern Europe, Western Europe, the Middle East, Africa, Central America, or Asia, IGM can assist in delivering Dulaglutide as per your requirements. For more information on international shipping options, contact us today.

What Is the procedure for buying Dulaglutide from Indian Generic Medicines?

To buy Dulaglutide from Indian Generic Medicines (IGM), patients need to fill out the order form or send an email to info@indiangenericmedicines.com. Alternatively, you can send a WhatsApp message to +91 8130290915 or call our TOLL-FREE number 1800-889-1064. After receiving your inquiry, we will provide you with the details regarding Trulicity- Dulaglutide’s price in India and the procurement process. Please note that your order will only be confirmed once we receive a valid prescription from your physician.

Is it safe to buy Trulicity (dulaglutide) pens online from India?

Yes, buying Trulicity (dulaglutide pen) online from India through Indian Generic Medicines (IGM) is safe, especially if the drug is not registered or unavailable in your country. IGM facilitates the legal export of Trulicity (dulaglutide 1.5 mg/0.5 mL) solution for injection to various countries, ensuring that you receive genuine medicine. Our service ensures compliance with all necessary regulations, providing a secure and reliable way to access Dulaglutide from India.