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Treosulfan is an alkylating agent. It is used to prepare patients for bone marrow transplants (hematopoietic stem cell transplantation). The treosulfan injection is used before the blood stem cell transplantation in adult patients with cancer and non-cancerous disorders and children and adolescents aged older than 30 days with cancer.

Dosage and Side Effects

The recommended dose of treosulfan injection is 10-14 g/m² body surface area administered by drip (infusion) into a vein over 2 hours for three days before the blood stem cell infusion. For adults, Emtreo injection is used together with fludarabine, and for children/adolescents, it is used along with fludarabine, and in most cases, together with thiotepa.

Most common adverse reactions in adults and children include infections, nausea (feeling sick), stomatitis (inflammation of the lining of the mouth), vomiting, diarrhea, and bellyache. Tiredness, low white blood cell counts with fever, high blood levels of bilirubin are also reported in adult patients, and rash also affects children.

Warning and Precautions

  • Patients with treosulfan 5g injection should be monitored for blood cell counts frequently until recovery of the hematopoietic system.
  • Concomitant use/application of live attenuated vaccines is not allowed.
  • The treosulfan 5gm injection might impair fertility in men as well as women. Therefore, men must seek advice on cryo-conservation of sperm before treatment due to the probability of irreversible infertility.
  • Sexually active men/women of childbearing potential have to use apt and effective contraception while up to 6 months following treatment.
  • Use of treosulfan 5g injection is contraindicated during pregnancy.
  • Breast-feeding should be discontinued during treosulfan injection treatment.
  • Treosulfan injection has a moderate influence on the ability to drive as well as use machines.


What is Treosulfan 5gm?

The treosulfan 5gm is used as a part of a conditioning regimen in stem cell transplantation.

From which class of drug Treosulfan belongs? 

Treosulfan belongs to the class of drugs named bifunctional alkylating agents. 

How should Treosulfan be administered? 

The recommended dose of treosulfan injection should be administered by intravenous (IV) infusion over 30 minutes. 

From where can I buy Treosulfan? 

You can buy Treosulfan from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

The buyer should check the existing law in their home country before importing the product.

What is the procedure to buy Treosulfan from Indian Generic Medicines ? 

Patients can simply fill the order form or can send mail at Patients can also send WhatsApp messages to +91 8130290915 or can dial Toll-Free number: 18008891064. We will reply ASAP with the details of treosulfan cost and buying procedure.

Note:- The order will confirm only after the receipt of the Valid prescription of the Clinician.