Abciximab Injection

  • Medicine Name- AbcixiRel
  • API- Abciximab
  • Packaging- Single-use vial 
  • Strength- 5mL/vial
  • Manufactured by- Reliance Life Sciences
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Description

Abciximab injection is a FAB fragment of the chimeric human-murine monoclonal antibody 7E3 for used as an adjunct to percutaneous coronary intervention (PCI) for the prevention of cardiac ischemic events in patients undergoing percutaneous coronary intervention (PCI) and in patients with unstable angina who do not respond to conventional medical treatment when percutaneous coronary intervention (PCI) is scheduled within 24 hours.

AbcixiRel injection is also used for thrombolysis in patients with peripheral arterial occlusive disease and arterial thrombosis.

Dosage and Side Effects

The recommended dosage of Abciximab injection in adult patients is a 0.25 mg/kg intravenous (IV) bolus administered 10 to 60 minutes prior to starting percutaneous coronary intervention (PCI), followed by a continuous intravenous (IV) infusion of 0.125 µg/kg/min (to a maximum of 10 µg/min) for 12 hours.

Patients with unstable angina who do not respond to conventional treatment and who are scheduled to undergo percutaneous coronary intervention (PCI) within 24 hours may be treated with a 0.25 mg/kg intravenous (IV) bolus followed by an 18-24-hour intravenous (IV) infusion of 10 µg/min, concluding one hour after the percutaneous coronary intervention (PCI).

The most common side effects of Abciximab injection are bleeding, back pain, nausea, hypotension, and chest pain.

Warning and Precautions

  • Abciximab may increase the probability of bleeding, mainly in the existence of anticoagulation, e.g., from heparin, thrombolytics, or anticoagulants. The probability of major bleeding because of this drug may be increased in those receiving thrombolytics and should be weighed against the anticipated benefits.

  • Treatment with Abciximab 5mL requires close attention to all potential bleeding sites (including cutdown sites, catheter insertion sites, arterial and venous puncture sites, needle puncture sites, and genitourinary, gastrointestinal, and retroperitoneal sites).

  • Minimize arterial and venous punctures, IM injections, and use of urinary catheters, nasogastric tubes, nasotracheal intubation, and automatic blood pressure cuffs. When obtaining IV access, non-compressible sites need to be avoided. Document and monitor vascular puncture sites. Provide gentle care when removing dressings.

  • Monitor platelet counts prior to treatment, 2 to 4 hours following the bolus dosage of Abciximab injection, and at 24 hours or before discharge, whichever is first. In case a patient experiences an acute platelet decrease, additional platelet counts need to be determined.

  • In the event of critical uncontrolled bleeding or the need for emergency surgery, treatment with Abciximab needs to be discontinued. In case platelet function does not return to normal, it may be restored, at least in part, with platelet transfusions.

FAQ's

What is AbcixiRel?

AbcixiRel, a monoclonal antibody from Reliance Life Sciences is the first Indian abciximab biosimilar. It is used as an adjunct to percutaneous coronary intervention (PCI) to prevent acute ischemic cardiac events or complications.

What dosage forms AbcixiRel is supplied?

This therapeutic drug is supplied in a 5mL vial containing abciximab 10 mg.

How do I store abciximab?

Store the vials at 2-8°C (36-46°F). Never freeze or shake it. Never use beyond the expiration date. Discard any unused content left in the vial.

How much does abciximab cost in India?

Abciximab cost in India is very reasonable and can vary. To procure it legally, you can call us at (+91) 8130290915, TOLL-FREE: 1800-889-1064, Or Write us at info@indiangenericmedicines.com.

Can abciximab be used while I’m pregnant?

Abciximab may not be safe if used during pregnancy. Discuss with your doctor about the other ways to help control your condition during pregnancy. 

Can abciximab be used while breastfeeding?

Breastfeeding is not recommended while on abciximab. Discuss with your doctor if you are breastfeeding or intend to breastfeed.

Where can I get Abciximab at the best Price? 

Order abciximab at the best price today. We request you to Call/WhatsApp us at (+91) 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 or Write us at info@indiangenericmedicines.com. We are fully committed to providing you with the best abciximab price from India. That is why we’ll match the cost/price of any other existing suppliers/distributors in the market who require a medical prescription.

Is the abciximab available in India?

Abciximab is a (prescription drug, doctor-prescribed medication, or health care professional-prescribed medicine) pharmaceutical drug that can be legally dispensed against a medical prescription. Abciximab can be made available through the network of authorized distributors in India (Bangalore, Ahmedabad, Chennai, Mumbai, Kolkata, Hyderabad, Delhi, Pune, etc.)

Can You Send the Abciximab to Foreign Destinations?

Buy abciximab online at the best/lowest price from a leading supplier. Indian Generic Medicines (IGM) can assist in the delivery of abciximab; the doctor-prescribed medication to the UK, Canada, Australia, Philippines, UAE, Saudi Arabia, the USA, Thailand, China, South Africa, Zambia, Kazakhstan, Uzbekistan, Pakistan, Kuwait, Sri Lanka, Singapore, Sweden, Hong Kong, Turkey, Afghanistan, Malaysia, Qatar, Japan, Nepal, and many other countries.

What is the procedure to buy Abciximab from Indian Generic Medicines

Patients can fill out the order form or send mail to info@indiangenericmedicines.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008891064. We will reply ASAP with the details of the abciximab price and the procurement procedure.

Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy abciximab online from India?

Yes, one can buy abciximab online from India-based Indian Generic Medicines (IGM) if it is not (yet) registered or is unavailable in their respective country. We can facilitate the supply/export of abciximab through legal channels.