The platinum-based medication oxaliplatin is advised to be used with the infusional 5-fluorouracil/leucovorin, and it is suggested for:
- adjuvant therapy for individuals with stage 3 colon cancer who have had the original tumor completely removed.
- therapy for colon cancer that has progressed.
Dosage and Side Effects
You should receive an Oxaliplatin injection through your veins (blood vessels) under the guidance of a licensed medical professional who is skilled in the administration of cancer chemotherapy drugs. Only when appropriate diagnostic and therapeutic choices or facilities are readily and quickly available can therapy and problems be managed precisely.
Anemia, exhaustion, neutropenia, thrombocytopenia, nausea, emesis, elevated transaminases and alkaline phosphatase, diarrhea, stomatitis, and peripheral sensory neuropathy are among the most frequent adverse effects. There have been reports of other side effects, including severe adverse reactions.
What is Oxaliplatin Injection used for?
Oxaliplatin Injection, in combination with infusional 5-fluorouracil/leucovorin, is recommended for adjuvant therapy in individuals with stage 3 colon cancer post-complete tumor removal. It is also used in the therapy of progressing colon cancer.
How is Oxaliplatin Injection administered?
Oxaliplatin 50 mg and 100 mg Injection is given intravenously by a qualified healthcare professional experienced in administering chemotherapy. Adequate diagnostic and therapeutic facilities should be readily available for precise management of therapy and potential complications.
What are the common side effects of Oxaliplatin Injection?
Common side effects may include anemia, fatigue, neutropenia, thrombocytopenia, nausea, vomiting, increased liver enzymes, diarrhea, stomatitis, and peripheral sensory neuropathy. Other severe adverse reactions have been reported.
What precautions should be taken while using Oxaliplatin Injection?
Patients using medications containing platinum, like Oxaliplatin, may experience adverse reactions, more commonly observed in women. Close monitoring is required for any signs of rash, hives, redness, itching, wheezing, or low blood pressure. Regular monitoring of blood counts and liver and kidney function is advised before each treatment cycle.
Are there any specific precautions for patients receiving Oxaliplatin Injection?
Patients receiving Oxaliplatin Injection, especially at higher doses, might need constant monitoring if they are on oral anticoagulants. Additionally, they should avoid cold environments and exposure to cold items and refrain from using ice or ice packs on their bodies. Persistent vomiting, diarrhea, dehydration, difficulty breathing, or signs of allergic reactions should prompt immediate contact with a healthcare professional.