Dobutamine in 5% Dextrose Injection is recommended when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures. Experience with intravenous dobutamine in controlled trials does not extend beyond 48 hours of repeated boluses and/or continuous infusions.Â
Dobutamine in 5% Injection is administered intravenously through a suitable intravenous catheter or needle. A calibrated electronic infusion device is recommended for controlling the rate of flow in mL/hour or drops/minute. Infusion of dobutamine should be started at a low rate (0.5 to 1.0 µg/kg/min) and titrated at intervals of a few minutes, guided by the patient’s response, including systemic blood pressure, urine flow, frequency of ectopic activity, heart rate, and measurements of cardiac output, central venous pressure, and/or pulmonary capillary wedge pressure.
The common side-effects of Dobutamine are anorexia, nausea, vomiting, tremor, anxiety, palpitations, headache, shortness of breath, and anginal and nonspecific chest pain.
Dobutamine hydrochloride may cause a marked increase in heart rate or blood pressure, especially systolic pressure.
Dobutamine may precipitate or exacerbate ventricular ectopic activity, but it rarely has caused ventricular tachycardia.Â
During the administration of dobutamine, as with any adrenergic agent, ECG and blood pressure should be continuously monitored. Do not administer unless the solution is clear and the container is undamaged. Discard unused portions.
Healthcare professionals do not recommend Dobutamine to potential females who want to get pregnant as this drug has potential risks to the fetus.
What is the drug dobutamine used for?
The drug Dobutamine is recommended when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.
What is the difference between dopamine and dobutamine?
Dobutamine resembles dopamine chemically and is an analog of isoproterenol. It is relatively cardioselective at dosages used in clinical practice, with its main action being on beta 1-adrenergic receptors. Unlike dopamine, it does not have any effect on specific dopaminergic receptors.
What drug class is dobutamine?
Dobutamine belongs to the class of Inotropic Agents.
What is the cost of Dobutamine?
Dobutamine cost is reasonable and one can readily purchase this medication from any nearby certified pharmaceutical suppliers worldwide. To know more about this medicine contact us at info@indiangenericmedicines.com.
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