What is the generic name of Tagrisso?
Generic name of Tagrisso is Osimertinib.
Who is the manufacturer of Tagrisso 80mg and 40mg?
Tagrisso is manufactured by Astra Zeneca Sweden and marketed by Astra Zeneca Pharma Ltd.
Is Tagrisso approved by USA FDA?
Yes, Tagrisso is approved by FDA. The product was approved in 2017.
What is the dosage form of Tagrisso?
Tagrisso is available as 80 mg and 40mg in tablet form.
What are the storage conditions of Tagrisso 80mg and 40mg?
The product must be kept at Room Temperature. The product should be Stored at 20° to 25°C (68° to 77°F). Excursions are permitted between 15°C to 30°C (59°F to 86°F)
How Tagrisso 80mg and 40mg is supplied?
Tagrisso is supplied as pack of 10 tablets of 80mg strength.
How does Tagrisso 80 mg and 40mg work?
Osimertinib is kinase inhibitor of the epidermal growth factor receptor (EGFR), which binds irreversibly to certain mutant forms of EGFR (T790M, L858R, and exon 19 deletion) at approximately 9-fold lower concentrations than wild-type. In cultured cells and animal tumor implantation models, osimertinib exhibited anti-tumor activity against NSCLC lines harboring EGFR-mutations (T790M/L858R, L858R, T790M/exon 19 deletion, and exon 19 deletion) and, to a lesser extent, wild-type EGFR amplifications. Two pharmacologically-active metabolites (AZ7550 and AZ5104 circulating at approximately 10% of the parent) with similar inhibitory profiles to osimertinib have been identified in the plasma after oral administration of osimertinib. AZ7550 showed a similar potency to osimertinib, while AZ5104 showed greater potency against exon 19 deletion and T790M mutants (approximately 8-fold) and wild-type (approximately 15-fold) EGFR. In vitro, osimertinib also inhibited the activity of HER2, HER3, HER4, ACK1, and BLK at clinically relevant concentrations
What is Tagrisso 80 mg used for?
TAGRISSO is indicated for the treatment of patients with metastatic epidermal growth factor receptor (EGFR) T790M mutation-positive non-small cell lung cancer (NSCLC), as detected by an FDA-approved test, who have progressed on or after EGFR tyrosine kinase inhibitor (TKI) therapy.
How many brands of Tagrisso 80 mg are available in India?
Tagrisso is an innovator medicine. There are no generics available in India.
Is there any generic or bio similar available for Tagrisso 80 mg.
Generics of Tagrisso are available in other countries (like Bangladesh and Sri lanka)
What is the price of Tagrisso 80 mg in India?
You can call or WhatsApp (+91) 9650877511 or send mail to email@example.com to know the price.
Other information about Tagrisso 80 mg.
Guardant Health signed a multi-year agreement with AstraZeneca to develop blood-based companion diagnostic (CDx) tests supporting the commercialization of AstraZeneca’s oncology portfolio based on Guardant’s comprehensive liquid biopsy platform. Under the terms of the agreement, Guardant Health will develop and pursue FDA approval for a Guardant360 CDx test for Tagrisso (osimertinib), AstraZeneca’s third-generation epidermal growth factor receptor (EGFR) inhibitor in advanced non-small cell lung cancer (NSCLC). Use of the assay will help identify patients that may respond to Tagrisso via a minimally invasive blood test.
Is it safe to buy Tagrisso in India from local distributor?
It is always better to check the credential of the person / distributor before confirming.
As per the legal guidelines, only patients can import the product after getting proper Documentation.