Goserelin

API- Goserelin Acetate Packaging- Implant Strength- 3.6mg/10.8mg

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Description

Goserelin specifically is a GnRH agonist used for the treatment of:

  • Prostate cancer
  • Breast cancer
  • Endometriosis
  • Uterine fibroids
  • Female infertility

Dosage and Side Effects

The recommended goserelin dose is 3.6mg, should be administered subcutaneously every 28 days into the anterior abdominal wall below the navel line using an aseptic technique under the supervision of a healthcare practitioner.

Most common adverse reactions in men include hot flashes, decreased erections, sexual dysfunction, lower urinary tract symptoms and tumor flare. Most common adverse reactions in women treated for breast cancer, dysfunctional uterine bleeding or endometriosis include: hot flushes, sweating, headache, acne, emotional lability, decreased libido, depression, vaginitis, breast atrophy, peripheral edema, seborrhea and tumor flare.

Warning and Precautions

  • Women should be apprised against becoming pregnant during treatment with goserelin 10.8 mg/3.6 mg.
  • Patients should be monitored for the levels of blood glucose and glycosylated hemoglobin (HbA1c) periodically.
  • Patients with GnRH agonists need to be monitored for the symptoms and signs suggestive of the development of cardiovascular disease.
  • Additional caution must be imposed when administering zoladex to patients with reduced BMI or to patients taking full dose anticoagulation.
  • A woman must not begin treatment with zoladex 10.8 mg/3.6 mg in case she has undiagnosed abnormal vaginal bleeding, or is allergic to any of the components of this medication.
  • Menstruation should stop with effective goserelin doses. Patient must notify her doctor in case regular menstruation persists. Patients missing 1 or more successive zoladex doses may have breakthrough menstrual bleeding.

FAQ's

From which class of drug Goserelin belongs?

Goserelin specifically belongs to the class of drugs named Luteinizing Hormone-Releasing Hormone (LHRH) analogues. 

What are commonly reported side effects of Goserelin?

Bone pain, headache, hot flushes, stomach upset, difficulty urinating, depression, weight gain, decreased erections and reduced sexual desire are the common goserelin side effects. How should Goserelin be administered?

The recommended dose of Goserelin injection should be administered by subcutaneous injection as an implant every 28-days for the duration of the treatment.  How does Goserelin work?

Classified as a LHRH agonist, goserelin works in order to tell the pituitary gland placed in the brain to interrupt producing the luteinizing hormone, which (in men) stimulates the testicles in order to release testosterone and (in women) stimulates the ovaries in order to release estrogen. How much does zoladex cost? The average wholesale price for zoladex 3.6 mg is around 53,136 INR for a supply of a single implant. From where I can buy Goserelin? You can buy zoladex goserelin from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product. The buyer should check the existing law in their home country before importing the product.