Goserelin 3.6mg & 10.8mg Implant

Goserelin 3.6mg & 10.8mg Implant

  • Medicine Name– Zoladex
  • API- Goserelin Acetate 
  • Packaging- Implant 
  • Strength- 3.6mg/10.8mg
  • Marketed by- AstraZeneca
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Description

In particular, goserelin is a GnRH agonist that is used to treat:

  • Cancer of the prostate
  • Breast cancer
  • Endometriosis
  • uterine fibroids
  • Infertility in women

Dosage and Side Effects

Under the direction of a healthcare professional, 3.6 mg of goserelin should be subcutaneously injected every 28 days into the anterior abdomen wall below the navel line while adhering to aseptic protocol.

Hot flashes, fewer erections, sexual dysfunction, symptoms related to the lower urinary system, and tumour flare-ups are among the most frequent side effects experienced by men. Hot flushes, sweating, headaches, acne, mental instability, decreased libido, depression, vaginitis, breast atrophy, peripheral edoema, seborrhea, and tumour flare-ups are among the most frequent side responses seen by women receiving treatment for breast cancer, endometriosis, or dysfunctional uterine haemorrhage.

Warning and Precautions

  • It is important to warn women not to get pregnant when using goserelin 10.8 mg/3.6 mg.

  • Periodically check the levels of glycosylated haemoglobin (HbA1c) and blood glucose in patients.

  • GnRH agonist users should be closely watched for any symptoms or indicators that point to the possible development of cardiovascular disease.

  • It is necessary to use extra caution while giving zoladex to patients who have a lower body mass index or who are on full dose anticoagulation.

  • If a woman has undetected abnormal vaginal bleeding or is allergic to any of the medication’s ingredients, she should not start using zoladex 10.8 mg/3.6 mg.

  • Effective goserelin dosages should cause the menstrual cycle to end. If the patient’s regular menstruation continues, she needs to let her doctor know. Individuals who skip one or more consecutive doses of zoladex may experience breakthrough menstrual bleeding.

FAQ's

From which class of drug Goserelin belongs?

Goserelin specifically belongs to the class of drugs named Luteinizing Hormone-Releasing Hormone (LHRH) analogues.

What are commonly reported side effects of Goserelin?

Bone pain, headache, hot flushes, stomach upset, difficulty urinating, depression, weight gain, decreased erections and reduced sexual desire are the common goserelin side effects.

How should Goserelin be administered?

The recommended dose of Goserelin injection should be administered by subcutaneous injection as an implant every 28-days for the duration of the treatment.

How does Goserelin work?

Classified as a LHRH agonist, goserelin works in order to tell the pituitary gland placed in the brain to interrupt producing the luteinizing hormone, which (in men) stimulates the testicles in order to release testosterone and (in women) stimulates the ovaries in order to release estrogen.

How much does zoladex cost?

The average wholesale price for zoladex 3.6 mg is around 53,136 INR for a supply of a single implant.

From where I can buy Goserelin?

You can buy zoladex goserelin from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product. The buyer should check the existing law in their home country before importing the product.

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