Cabozantinib Tablets

  • Medicine Name- Cazanat
  • API- Cabozantinib
  • Packaging- 30 Tablets
  • Strength- 20 mg/40 mg/60 mg 
  • Manufactured by- Natco Pharma
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Cabozantinib Tablet is a prescription medicine called a tyrosine kinase inhibitor (TKI) used for the treatment of:

  • patients with advanced renal cell carcinoma (RCC). 
  • patients with advanced renal cell carcinoma, as a first-line treatment in combination with nivolumab.
  • patients with hepatocellular carcinoma (HCC) who have previously been treated with medicine sorafenib.
  • adult and pediatric patients aged 12 years and older with locally advanced or metastatic differentiated thyroid cancer (DTC) that has progressed following prior VEGFR-targeted therapy and who are radioactive iodine-refractory or ineligible.

Dosage and Side Effects

Renal Cell Carcinoma (RCC): The recommended dosage of Cabozantinib tablets for Renal Cell Carcinoma (RCC) as a single agent is 60 mg and in combination with nivolumab is 40 mg once daily without food until disease progression or unacceptable toxicity. Nivolumab is used as 240 mg every 2 weeks (30-minute IV infusion) or 480 mg every 4 weeks (30-minute IV infusion).

Hepatocellular Carcinoma: The recommended dosage for patients with Hepatocellular Carcinoma as a single agent is 60 mg once daily until disease progression or unacceptable toxicity administered as recommended.

Differentiated Thyroid Cancer (DTC): The recommended dosage for patients with Differentiated Thyroid Cancer (DTC) as a single agent for adult and pediatric patients aged 12 years and older with BSA greater than or equal to 1.2 m2 is 60 mg once daily until disease progression or unacceptable toxicity administered as recommended.

The recommended dosage of Cabozantinib as a single agent in pediatric patients aged 12 years and older with BSA less than 1.2 m2 is 40 mg once daily until disease progression or unacceptable toxicity administered as recommended.

The most common side effects of Cabozantinib in patients with renal cell carcinoma (RCC), hepatocellular carcinoma (HCC), and differentiated thyroid cancer (DTC) are as follows:

  • As a single agent: nausea, weight decrease, constipation, vomiting, diarrhea, PPE, decreased appetite, fatigue, hypertension.
  • In combination with nivolumab: musculoskeletal pain, decreased appetite, hepatotoxicity, PPE, diarrhea, hypothyroidism, nausea, fatigue, stomatitis, rash, hypertension, dysgeusia, abdominal pain, cough, and upper respiratory tract infection.

Warning and Precautions

  • Severe and fatal hemorrhages may develop with Cabozantinib 20 mg/40 mg/60 mg. Discontinue Cabozantinib for Grade 3/4 hemorrhage. Do not administer this therapeutic drug to patients who have a recent history of hemorrhage, including hematemesis, hemoptysis, or melena.  
  • Fistulas and gastrointestinal (GI) perforations, including fatal cases, may occur in patients treated with Cabozantinib. Monitor patients for fistulas and perforations, including abscess and sepsis. Stop treatment in patients who experience a Grade 4 fistula or a gastrointestinal (GI) perforation.
  • Cabozantinib can cause hypertension, including hypertensive crisis. Do not initiate this treatment in patients with uncontrolled hypertension. Monitor blood pressure regularly during treatment.
  • Cabozantinib in combination with nivolumab can cause hepatotoxicity with higher frequencies of Grades 3/4 ALT and AST elevations compared to Cabozantinib alone. Monitor liver enzymes prior to initiating and periodically throughout treatment.
  • Proteinuria may occur in patients receiving Cabozantinib 60 mg/40 mg/20 mg therapy. Monitor urine protein regularly during treatment. Discontinue the use of this medicinal product in those who develop nephrotic syndrome.


What is a Cazanat?

Cazanat is a generic of Cometriq/Cabometyx that contains Cabozantinib as the main component. This anti-cancer medicine treats medullary thyroid cancer, renal cell carcinoma (RCC), and hepatocellular carcinoma.

Who has launched the generic Cazanat?

Natco Pharma has launched the generic Cazanat, as 20 mg, 40 mg, and 60 mg tablets for oral use or administration.

How do I take Cabozantinib? 

Cabozantinib is commercially available as a 20 mg, 40 mg, and 60 mg tablet which should be taken by mouth (orally). 

How do I store Cabozantinib?

Store the tablets of Cabozantinib at room temperature (not beyond 30⁰C) in the original container.

How much does Cabozantinib cost in India?

Cabozantinib tablets cost in India is reasonable and can vary. To procure this kinase inhibitor legally, you can call us at (+91) 8130290915, TOLL-FREE: 1800-889-6064, Or Write us at

Can Cabozantinib be used while I’m pregnant?

Cabozantinib tablets may be unsafe if used during pregnancy. Talk to your provider about the best way to help control your disease during pregnancy. 

Can Cabozantinib be used while breastfeeding?

Breastfeeding is not recommended while on Cabozantinib. Talk to your doctor if you are breastfeeding or want to breastfeed.

Where can I get Cabozantinib at the best Price? 

Order Cabozantinib tablet at the best price today. We request you to Call/WhatsApp us at (+91) 8130290915 or dial our TOLL-FREE Number: 1800-889-6064 or Write us at We are fully committed to providing you with the best Cabozantinib 20 mg/40 mg/60 mg price from India. That is why we’ll match the cost/price of any other existing suppliers/distributors in the market who require a medical prescription.

Is the Cabozantinib available in India?

Cabozantinib tablet is a (prescription drug, doctor-prescribed medicine, or health care professional-prescribed medication) pharmaceutical drug that can be legally dispensed against a medical prescription. The oral Cabozantinib can be made available through the network of authorized distributors in India. (Mumbai, Bangalore, Chennai, Ahmedabad, Kolkata, Hyderabad, Delhi, Pune, etc.)

Can You Send the Cabozantinib to Foreign Destinations?

Buy generic Cabozantinib tablets online at the best price from a leading supplier. Indian Generic Medicines can assist in the delivery of Cabozantinib; the doctor-prescribed medication to the UK, Canada, Australia, Sri Lanka, Philippines, the USA, South Africa, Kazakhstan, Saudi Arabia, Thailand, China, Uzbekistan, Zambia, Pakistan, Hong Kong, Turkey, Kuwait, Sweden, Afghanistan, Malaysia, Singapore, Qatar, Japan, Nepal, UAE, and many other countries.

What is the procedure to buy Cabozantinib from Indian Generic Medicines

Patients can fill out the order form or send mail to Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008896064. We will reply ASAP with the details of the Cabozantinib 20 mg/40 mg/60 mg price and the procurement procedure.

Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy Cazanat (Cabozantinib) online from India?

Yes, one can buy Cazanat (Cabozantinib) tablet online from India-based Indian Generic Medicines if it is not (yet) registered or is unavailable in their respective country. We can facilitate the supply of Cabozantinib tablets through legal channels.