Velpatasvir + Sofosbuvir

  • Medicine Name- Velpanat 
  • API- Sofosbuvir/Velpatasvir
  • Packaging- 28 Tablets
  • Strength- 400 mg/100 mg
  • Manufactured by- Natco Pharma
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Velpanat Tablet is a fixed-dose combination (FDC) drug of sofosbuvir, a hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitor, and velpatasvir, an HCV NS5A inhibitor, and is approved for the treatment of adults and pediatric patients aged 3 years and older with chronic hepatitis C virus (HCV) genotype 1, 2, 3, 4, 5, or 6 infection without cirrhosis or with compensated cirrhosis, or with decompensated cirrhosis for use together with ribavirin.

Dosage and Side Effects

The recommended dosage of Velpanat in adults is one tablet (sofosbuvir 400 mg and velpatasvir 100 mg) taken by mouth once daily with or without food. When used with Velpanat, the recommended dosage of the drug ribavirin is based on the body weight (administered with food): 1,000 mg daily for patients not more than 75 kg and 1,200 mg for those weighing at least 75 kg, divided and given twice daily.

The recommended dosage of Velpanat in pediatric patients aged three years and older is based on body weight. Patients weighing less than 17 kg can take 150 mg/37.5 mg daily, patients weighing 17 kg to less than 30 kg can take 200 mg/50 mg daily, and those weighing at least 30 kg can take one 400 mg/100 mg tablet once daily with or without food.

The most common side effects of Sofosbuvir/Velpatasvir tablets are fatigue, nausea, anemia, headache, insomnia, vomiting, and diarrhea.

Warning and Precautions

  • Test all the respective patients for evidence of current or previous HBV infection by measuring HBsAg (hepatitis B surface antigen) and anti-HBc (hepatitis B core antibody) before initiating HCV therapy with sofosbuvir and velpatasvir.
  • Cardiac monitoring in an in-patient setting for the initial 48 hours of coadministration is needed, following which outpatient or self-monitoring of the heart rate should be done on a daily basis through at least the initial couple of weeks of treatment.
  • Counsel patients about the probability of symptomatic bradycardia. Those who develop signs or symptoms of bradycardia must seek medical assessment immediately. Symptoms may include dizziness, fainting, malaise, weakness, tiredness, chest pains, shortness of breath, or confusion.
  • Avoid using velpanat and ribavirin combination regimens in those for whom the drug ribavirin is contraindicated. Certain adverse reactions may occur with this combination regimen.


What is Velpanat?

Velpanat, a generic version of Epclusa, is a fixed-dose combination medicine for the treatment of chronic hepatitis C virus (HCV).

Who has launched the generic Velpanat?

Natco Pharma Ltd has launched the generic Velpanat, as a fixed-dose combination of Sofosbuvir 400 mg and Velpatasvir 100 mg tablets.

How do I store Sofosbuvir/Velpatasvir?

Store the tablets of Sofosbuvir 400 mg/Velpatasvir 100 mg below 30°C (86°F). Dispense it only in the original container. 

How much does Sofosbuvir/Velpatasvir cost in India?

Sofosbuvir/Velpatasvir cost in India is very reasonable and can vary. To procure it legally, you can call us at (+91) 8130290915, TOLL-FREE: 1800-889-1064, Or Write us at

Can Sofosbuvir/Velpatasvir be used while I’m pregnant?

Sofosbuvir/Velpatasvir may be unsafe if used during pregnancy. Talk to your healthcare provider for an alternative way to manage your disease in case you want to become pregnant or during pregnancy. 

Can Sofosbuvir/Velpatasvir be used while breastfeeding?

Breastfeeding is not recommended while on Sofosbuvir/Velpatasvir. Talk to your doctor in case you are breastfeeding or intend to breastfeed.

Where can I get Velpanat at the best Price? 

Order Velpanat at the best price today. We request you to Call/WhatsApp us at (+91) 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 or Write us at We are fully committed to providing you with the best Sofosbuvir/Velpatasvir price from India. That is why we’ll match the cost/price of any other existing suppliers/distributors/facilitators in the market who require a medical prescription.

Is the Velpanat available in India?

Velpanat is a (prescription drug, doctor-prescribed medication, or health care professional-prescribed medicine) pharmaceutical drug that can be legally dispensed against a medical prescription. Velpanat can be made available through the network of authorized distributors in India. (Mumbai, Ahmedabad, Hyderabad, Bangalore, Kolkata, Chennai, Delhi, Pune, etc.)

Can You Send the Velpanat to Foreign Destinations?

Buy Sofosbuvir/Velpatasvir online at the lowest price from a leading supplier. Indian Generic Medicines (IGM) can assist in the delivery of Velpanat; the doctor-prescribed medication to the USA, the UK, UAE, Canada, Philippines, Australia, Saudi Arabia, Thailand, China, Kazakhstan, Zambia, Pakistan, South Africa, Uzbekistan, Kuwait, Hong Kong, Sweden, Turkey, Afghanistan, Singapore, Malaysia, Qatar, Japan, Nepal, Sri Lanka, and many other countries.

What is the procedure to buy Velpanat from Indian Generic Medicines

Patients can fill out the order form or send mail to Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008891064. We will reply ASAP with the details of the Velpanat tablet price and the procurement procedure.

Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy Sofosbuvir-Velpatasvir (Velpanat) online from India?

Yes, one can buy Sofosbuvir-Velpatasvir (Velpanat) online from India-based Indian Generic Medicines (IGM) if it is not (yet) registered or is unavailable in their respective country. We can help facilitate the supply/export of Sofosbuvir/Velpatasvir tablets through legal channels.