Fulvestrant Injection

  • Medicine Name- Fulzos
  • API- Fulvestrant
  • Pack Size- 5 ml Single dose vial
  • Strength-  250mg/5ml
  • Manufactured by- Hetero Healthcare Limited
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Description

The oestrogen receptor antagonist Fulvestrant 250mg Injection is used to treat the following conditions:

  • In postmenopausal women undergoing disease progression, HR +Ve metastatic breast cancer is present.
  • Palbociclib, HR + Ve, and HER2 – Ve advanced breast cancer in women whose disease progressed following endocrine therapy.

Dosage and Side Effects

The recommended dose of fulvestrant is 500 mg, which should be injected intramuscularly into the buttocks slowly over the course of one to two minutes. The injection should be given as two 5 mL shots, one in each buttock, on the first, fifteenth, and thirty-ninth days, and then once a month after that.

The most frequent side effects include hot flashes, musculoskeletal discomfort, bone pain, arthralgia, headache, injection site pain, pain in the extremities, constipation, coughing, back pain, fatigue, anorexia, asthenia, and dyspnea.

FAQ's

From which class of drug Fulvestrant belongs?

Fulvestrant specifically belongs to the class of drugs named estrogen receptor antagonists. 

What are the alternate brands of Fulvestrant Injection?

  • Fulvenat 250mg InjectionInjection (Natco Pharma Ltd) 
  • Fulvetraz 250mg Injection (Alkem Laboratories Ltd) 
  • Strantas Injection (Intas Pharmaceuticals Ltd) 
  • Fuvestrol 250mg Injection (Cadila Pharmaceuticals Ltd) 
  • Fulviglen 250mg Injection (Glenmark Pharmaceuticals Ltd) 
  • Fasnorm 250mg Injection (Biocon Ltd) 
  • Celvestrant 250mg Injection (Celon Laboratories Ltd)

What are commonly reported side effects of Fulvestrant?

Hypersensitivity reactions, hot flushes, urinary tract infections, loss of appetite, blood clots in veins, headache, vomiting, diarrhea, elevated bilirubin, back pain and rashes are the common fulvestrant side effects

How should Fulvestrant be administered?

The recommended dose of fulvestrant injection should be administered by injection into a muscle.

How does Fulvestrant work?

As a SERD (Selective Estrogen Receptor Degrader), fulvestrant works in order to bind to the estrogen receptor and destabilize it, causing the cell’s protein degradation actions to kill it.

How much does faslodex cost?

The average wholesale fulvestrant injection price in India for 50 mg/mL is around 146,448 INR for a supply of 10 milliliters.