It is a fixed-dose combination of the medications tipracil and trifluridine. Tipiracil is an inhibitor of thymidine phosphorylase, while trifluridine is a nucleoside metabolic inhibitor.
It is advised for patients who have:
When taking Trifluridine Tipiracil tablets orally twice daily with food on Days 1 through Days 5 and Days 8 through Days 12 of each 28-day cycle, the recommended dosage is 35 mg/m2 up to a maximum of 80 mg per dose (based on the trifluridine component). This dosage should be continued until the disease progresses or the toxicity becomes intolerable. The tablet should be swallowed whole by the patient.
Trifluridine Tipiracil side effects that occur most frequently include anaemia, thrombocytopenia, nausea, vomiting, diarrhoea, and neutropenia.
What is Trifluridine Tipiracil?
Trifluridine constitutes a thymidine-derived nucleoside analog, while Tipiracil acts as a thymidine phosphorylase inhibitor. This prescription medicine is utilized for treating colorectal and gastric cancer patients.
What comprises Trifluridine Tipiracil?
The active components in this medication encompass Trifluridine and tipiracil hydrochloride, while the inactive constituents include lactose monohydrate, pregelatinized starch, stearic acid, hypromellose, polyethylene glycol, titanium dioxide, ferric oxide, and magnesium stearate.
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