Sofosbuvir Velpatasvir

  • Packaging-28-Tablets
  • Strength- 400mg of sofosbuvir+100mg velpatasvir
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Velpanat (Sofosbuvir + Velpatasvir) Tablet is a fixed-dose combination of sofosbuvir 400 mg, a hepatitis C virus nucleotide analog NS5B polymerase inhibitor, and velpatasvir 100 mg, an HCV NS5A inhibitor, and is used for the treatment of adult patients with chronic HCV genotype 1 to 6 infection: 

  • Without cirrhosis or with compensated cirrhosis Child-Pugh A). 
  • With decompensated cirrhosis (Child-Pugh B and C) for use in combination with ribavirin

Dosage and Side Effects

The recommended dosage of Velpanat is one tablet taken orally once daily with or without food. One velpanat tablet contains 400 mg of sofosbuvir and 100 mg of velpatasvir. When used with Velpanat, the standard dosage of ribavirin depends on weight (administered with food): 1000 mg daily for patients less than 75 kg and 1200 mg for those weighing minimum 75 kg, divided and used twice daily. The starting dosage and on-treatment dosage of ribavirin may be reduced based on hemoglobin and creatinine clearance.

The most commonly reported sofosbuvir velpatasvir side effects include: headache, fatigue, anemia, nausea, insomnia and diarrhea.

Warning and Precautions

  • Do not use sofosbuvir velpatasvir tablets and ribavirin combination regimen in patients for whom ribavirin medication is contraindicated.
  • Patients should seek medical evaluation promptly for symptoms of bradycardia such as shortness of breath, near-fainting or fainting, chest pain, dizziness or lightheadedness, malaise, weakness, excessive tiredness, memory problems.
  • Patients should administer sofosbuvir 400 mg velpatasvir 100 mg once daily on a regular dosing schedule with or without food. Patients must not miss or skip doses and should take dosage for the duration as recommended by health specialists.
  • Patients should avoid pregnancy while on combination treatment with sofosbuvir velpatasvir and ribavirin and for 6 months after finishing the therapy. Patients should notify their health specialist in the event of a pregnancy.


What is Sofosbuvir Velpatasvir?

Sofosbuvir-velpatasvir tablet is a pangenotypic NS5A-NS5B inhibitor single-pill combination regimen that has potent mechanisms against HCV genotypes 1, 2, 3, 4, 5, and 6.

What dosage strengths Sofosbuvir Velpatasvir is supplied?

Sofosbuvir Velpatasvir Tablet is supplied as a coformulated, once-daily single-pill combination of sofosbuvir 400 mg and velpatasvir 100 mg. 

How is Sofosbuvir 400 mg Velpatasvir 100 mg administered?

The sofosbuvir 400 mg velpatasvir 100 mg comes as tablets for once daily oral administration. 

What type of drug is Sofosbuvir Velpatasvir? 

Sofosbuvir Velpatasvir tablet specifically is a combination antiviral medication. 

Where can I buy Sofosbuvir Velpatasvir Tablets? 

You can buy Sofosbuvir Velpatasvir tablet from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

The buyer should check the existing law in their home country before importing the product.