Velpanat is a fixed-dose combination of sofosbuvir 400 mg, a hepatitis C virus nucleotide analog NS5B polymerase inhibitor, and velpatasvir 100 mg, an HCV NS5A inhibitor, and is used for the treatment of adult patients with chronic HCV genotype 1 to 6 infection:
- without cirrhosis or with compensated cirrhosis Child-Pugh A).
- with decompensated cirrhosis (Child-Pugh B and C) for use in combination with ribavirin
Dosage and Side Effects
The recommended dosage of Velpanat is one tablet taken orally once daily with or without food. One velpanat tablet contains 400 mg of sofosbuvir and 100 mg of velpatasvir. When used with Velpanat, the standard dosage of ribavirin depends on weight (administered with food): 1000 mg daily for patients less than 75 kg and 1200 mg for those weighing minimum 75 kg, divided and used twice daily. The starting dosage and on-treatment dosage of ribavirin may be reduced based on hemoglobin and creatinine clearance.
The most commonly reported sofosbuvir velpatasvir side effects include: headache, fatigue, anemia, nausea, insomnia and diarrhea.
What is Sofosbuvir Velpatasvir?
Sofosbuvir-velpatasvir is a pangenotypic NS5A-NS5B inhibitor single-pill combination regimen that has potent mechanisms against HCV genotypes 1, 2, 3, 4, 5, and 6.
What dosage strengths Sofosbuvir Velpatasvir is supplied?
Sofosbuvir Velpatasvir is supplied as a coformulated, once-daily single-pill combination of sofosbuvir 400 mg and velpatasvir 100 mg.
How is Sofosbuvir 400 mg Velpatasvir 100 mg administered?
The sofosbuvir 400 mg velpatasvir 100 mg comes as tablets for once daily oral administration.
What type of drug is Sofosbuvir Velpatasvir?
Sofosbuvir Velpatasvir specifically is a combination antiviral medication.
Where can I buy Sofosbuvir Velpatasvir Tablets?
You can buy Sofosbuvir Velpatasvir from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.
The buyer should check the existing law in their home country before importing the product.