Trastuzumab

  • Medicine name- Hertraz 
  • API- Trastuzumab
  • Packaging- 1 Multi-Dose Vial/ 2 vials of BWFI
  • Strength- 440 mg
  • Manufactured by- Mylan Pharmaceuticals Pvt Ltd
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Description

A monoclonal antibody called trastuzumab Injection is used to treat stomach and breast cancer. It is only used to treat HER2 receptor-positive tumours.

Dosage and Side Effects

It is recommended that an experienced healthcare provider supervises the subcutaneous or intravenous administration of trastuzumab injection.

Trastuzumab Injection’s most frequent adverse effects are headaches, lightheadedness, joint and muscular discomfort, rash, nausea, dyspnea, dysphagia, soreness at the injection site, allergic reactions, and blood clots.

Warning and Precautions

  • Patients experiencing dyspnea at rest due to advanced complications from malignancy and associated comorbidities should avoid trastuzumab treatment, as it might elevate the risk of fatal infusion reactions or pulmonary events.
  • Consider managing patients with uncontrolled or prior history of hypertension before initiating trastuzumab injection therapy.
  • Avoid simultaneous administration of trastuzumab 440 mg injection and anthracyclines. Exercise caution when used before or after anthracyclines due to the prolonged half-life of trastuzumab (up to 28 weeks post-discontinuation).
  • Life-threatening infusion-related reactions may occur with trastuzumab injection administration.
  • Trastuzumab 440 mg Injection is specifically intended for patients with HER2-overexpressing tumors. Refer to the product monograph for detailed testing information.
  • Women of childbearing potential should be counseled to avoid pregnancy while on Hertraz 440 mg.

FAQ's

What components constitute Trastuzumab medication?

The active component in the medication is Trastuzumab, accompanied by inactive ingredients such as α,α-trehalose dihydrate, L-histidine HCl, L-histidine, and polysorbate 20.

Is Hertraz primarily used for breast cancer?

Yes, Hertraz (Trastuzumab 440 mg) Injection serves as a breast cancer treatment.

Has Trastuzumab received FDA approval?

Yes, Trastuzumab Injection has obtained FDA approval.

Is Trastuzumab considered cytotoxic?

Trastuzumab functions as a mediator of antibody-dependent cellular cytotoxicity.