Bendamustine

  • Medicine Name- Bendit 
  • API- Bendamustine 
  • Packaging- Single-dose vial
  • Strength- 100 mg/vial
  • Manufactured by- Natco Pharma Ltd
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Description

Bendamustine hydrochloride injection is an alkylating drug used for the treatment of adult patients with Chronic lymphocytic leukemia (CLL) and Indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within 6 months of treatment with medicine rituximab or a rituximab-containing regimen.

Dosage and Side Effects

Chronic lymphocytic leukemia (CLL): The recommended dosage of Bendamustine for CLL is 100 mg/m2 administered intravenously over 10 minutes on Days 1 and Days 2 of a 28-day cycle, up to six cycles. 

non-Hodgkin lymphoma (NHL): The recommended dose is 120 mg/m2 administered intravenously over 10 minutes on Days 1 & 2 of a 21-day cycle, up to eight cycles.

The most common side effects of Bendamustine injection in patients with Chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL) are as follows:

CLL: anemia, leukopenia, thrombocytopenia, neutropenia, lymphopenia, hyperbilirubinemia, pyrexia, nausea, vomiting.

NHL: weight decreased, lymphopenia, leukopenia, anemia, neutropenia, thrombocytopenia, headache, constipation, nausea, dyspnea, fatigue, vomiting, diarrhea, pyrexia, anorexia, cough, rash, and stomatitis.

Warning and Precautions

  • Bendamustine hydrochloride injection may be responsible for causing severe myelosuppression. Monitor complete blood counts (CBC), including leukocytes, hemoglobin (Hgb), neutrophils, and platelets frequently.

  • Infections, including sepsis, pneumonia, septic shock, hepatitis, and death may occur in adult and pediatric patients. Individuals with myelosuppression following this treatment should contact a physician promptly in case they have signs or symptoms of infection. 

  • Patients treated with Bendamustine 100 mg injection are at risk for reactivation of infections including hepatitis B, cytomegalovirus, Mycobacterium tuberculosis, and herpes zoster. Patients should undergo relevant measures (including clinical and laboratory monitoring, prophylaxis, and treatment) for infection and infection reactivation before administration.

  • Progressive multifocal leukoencephalopathy (PML), including fatal cases, may occur following treatment with bendamustine, primarily in conjunction with rituximab or obinutuzumab. Stop or reduce any concomitant chemotherapy or immunosuppressive therapy in those who develop PML.

  • Bendamustine extravasations may occur. Assure good venous access before starting medication infusion and monitor the intravenous (IV) infusion site for redness, swelling, infection, pain, and necrosis during and after administration of Bendamustine HCL injection

FAQ's

What is Bendit?

Bendit is a generic of Treanda that contains Bendamustine as the main component. This drug is used for the treatment of patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL). 

Who has launched the generic Bendit?

Natco Pharma Ltd has launched the generic Bendit, as 100mg/vial for intravenous (IV) administration.

How do I store Bendamustine?

Store bendamustine hydrochloride 100 mg injection in refrigerator, 2-8°C (36-46°F). 

How much does Bendamustine cost in India?

Bendamustine 100 mg cost in India is very reasonable and can vary. To procure it legally, you can call us at (+91) 8130290915, TOLL-FREE: 1800-889-1064, Or Write us at info@indiangenericmedicines.com.

Can Bendamustine be used while I’m pregnant?

Bendamustine Injection may be unsafe if used during pregnancy. Contact your clinician about the best way to control your disease/condition during pregnancy. 

Can Bendamustine be used while breastfeeding?

Breastfeeding is not recommended while on Bendamustine injection. Contact your clinician if you are breastfeeding or intend to breastfeed.

Where can I get Bendamustine at the best Price? 

Order Bendamustine at the best price today. We request you to Call/WhatsApp us at (+91) 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 or Write us at info@indiangenericmedicines.com. We’re fully committed to providing you with the best Bendamustine 100 mg price from India. That is why we’ll match the cost/price of any other existing suppliers/distributors in the market who require a medical prescription.

Is the Bendamustine available in India?

Bendamustine is a (prescription drug, doctor-prescribed medicine, or health care professional-prescribed medication) pharmaceutical drug that can be legally dispensed against a medical prescription. Generic Bendamustine can be made available through the network of authorized distributors in India. (Mumbai, Bangalore, Ahmedabad, Kolkata, Hyderabad, Chennai, Delhi, Pune, etc.)

Can You Send the Bendamustine to Foreign Destinations?

Buy generic Bendamustine online at the lowest price from a leading supplier. Indian Generic Medicines (IGM) can assist in the delivery of Bendamustine; the doctor-prescribed medication to the UK, Canada, China, South Africa, Australia, Philippines, the USA, Saudi Arabia, Thailand, Kazakhstan, Uzbekistan, Sri Lanka, Zambia, Pakistan, Kuwait, Malaysia, Singapore, Sweden, Hong kong, UAE, Turkey, Afghanistan, Qatar, Japan, Nepal, and many other countries.

What is the procedure to buy Bendamustine from Indian Generic Medicines

Patients can fill out the order form or send mail to info@indiangenericmedicines.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008891064. We will reply ASAP with the details of the Bendamustine 100 mg price and the procurement procedure.

Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy Bendamustine (Bendit) online from India?

Yes, one can buy Bendamustine (Bendit) online from India-based Indian Generic Medicines if Bendit is not (yet) registered or is unavailable in your respective country. We can facilitate the supply/export of generic Bendit through legal channels.