Idarubicin Hydrochloride Injection

  • Medicine name- Infimab
  • API- Idarubicin Hydrochloride
  • Pack Size- 1 ml injection vial
  • Strength- 20 mg
  • Marketed By: Neon Laboratories Ltd
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Idarubicin Hydrochloride is an anthracycline antileukemic drug indicated for the treatment of: 

  • Acute non-lymphocytic leukemia (ANLL) as a first line in adult patients. 
  • Acute lymphocytic leukemia (ALL) as a second line in adults and children. 
  • Chronic myelogenous leukemia in a blast crisis.
  • Advanced breast cancer.

Dosage and Side Effects

Idarubicin Hydrochloride intravenous injection in combination with other drugs daily should be given by continuous infusion. The dosage of Idarubicin Hydrochloride is usually calculated on the basis of total body surface area.

Most common adverse reactions include Nausea, Vomiting, Diarrhea, Sores in the mouth and throat, Stomach pain, Headache, Joint pain, Hair loss, Rash, and Redness/blisters on the palms and soles.

Warning and Precautions

  • The idarubicin 5 mg must be administered only under the supervision of a healthcare practitioner experienced in the use of cytotoxic chemotherapy.

  • Avoid using this drug in patients with pre-existing bone marrow depression induced by the radiotherapy unless the benefit warrants the risk.

  • The idarubicin hydrochloride is contraindicated in pregnant women or women wishing to become pregnant.

  • Patients should be assessed for cardiac function before undergoing treatment with Idarubicin Hydrochloride 5 mg and must be monitored throughout therapy in order to minimize the risk of incurring severe cardiac impairment.

  • Men as well as women should seek advice on fertility preservation prior to starting treatment with idamycin.

  • Women of childbearing potential should be instructed to not become pregnant while on treatment.


What are the ingredients in the medicine Idarubicin?

The active ingredient in the medicine is Idarubicin hydrochloride, and the inactive ingredient is Lactose NF.

Is Idarubicin cytotoxic?

The medicine Idarubicin is a sterile, semi-synthetic antineoplastic (cytotoxic) anthracycline drug.

From which class of drug Idarubicin belongs?

The idarubicin hydrochloride belongs to the class of drugs named antitumor antibiotics.

What are commonly reported side effects of Idarubicin?

Nausea, diarrhea, stomach cramps, and vomiting are commonly reported idarubicin side effects

How should Idarubicin be administered?

The idarubicin 5 mg must be administered only by injection slowly into a vein. Avoid giving by injection into a muscle or under the skin.

How does Idarubicin work? 

Falls under anthracyclines class of medicines, zavedos specifically works by slowing or resisting the growth of cancer cells in the body.