Trastuzumab

  • Medicine Name- Canmab
  • API- Trastuzumab
  • Packaging- Vials
  • Strength- 440 mg/150 mg
  • Manufactured by- Biocon Ltd
Get an Enquiry
Category:

Description

Trastuzumab is a HER2/neu receptor antagonist used for the treatment of patients with HER2-overexpressing breast cancer and for the treatment of HER2-overexpressing metastatic gastric or gastroesophageal junction adenocarcinoma.

Dosage and Side Effects

Adjuvant Treatment of HER2-Overexpressing Breast Cancer: Administer at either: 

  • Initial dose of 4 mg/kg as an IV infusion over 90 minutes, then 2 mg/kg as an IV infusion over 30 minutes weekly for 12 weeks (with paclitaxel or docetaxel) or 18 weeks (with docetaxel/carboplatin). One week after the last weekly dose of Trastuzumab, administer 6 mg/kg as an IV infusion over 30 to 90 minutes every 3 weeks to complete a total of 52 weeks of therapy, or 
  • Initial dose of 8 mg/kg as an IV infusion over 90 minutes, then 6 mg/kg as an IV infusion over 30 to 90 minutes every 3 weeks for 52 weeks. 

Metastatic HER2-Overexpressing Breast Cancer: Administer an initial dose of 4 mg/kg via a 90-minute IV infusion, followed by weekly doses of 2 mg/kg administered as 30-minute IV infusions.

Metastatic HER2-Overexpressing Gastric Cancer: Initial dose of 8 mg/kg as an IV infusion over 90-minute, followed by 6 mg/kg as an IV infusion over 30 to 90 minute, every 3 weeks.

The most common side effects of Trastuzumab in patients with Adjuvant Breast Cancer, Metastatic Breast Cancer, and Metastatic Gastric Cancer are as follows:

  • Adjuvant Breast Cancer: headache, diarrhea, nausea, and chills.
  • Metastatic Breast Cancer: fever, chills, headache, infection, congestive heart failure, insomnia, cough, and rash.
  • Metastatic Gastric Cancer: fatigue, anemia, weight loss, neutropenia, diarrhea, stomatitis, fever, upper respiratory tract infections, mucosal inflammation, nasopharyngitis, thrombocytopenia, and dysgeusia.

Warning and Precautions

  • Trastuzumab may lead to various cardiac issues such as left ventricular cardiac dysfunction, arrhythmias, hypertension, disabling cardiac failure, cardiomyopathy, and cardiac death. Additionally, it can cause a decrease in left ventricular ejection fraction (LVEF) without symptoms. Ensure comprehensive cardiac evaluation, including medical history, physical examination, and LVEF assessment via echocardiogram or MUGA scan.
  • Infusion reactions might arise. Patients should undergo evaluation and vigilant monitoring until all signs and symptoms completely resolve. Permanent discontinuation is strongly recommended for all patients experiencing severe infusion reactions.
  • Trastuzumab may harm unborn babies if given to pregnant women. Before starting treatment, confirm the pregnancy status of women capable of becoming pregnant. Women in this category should use reliable contraception during treatment and for 7 months after the last dose of Trastuzumab.
  • Using Trastuzumab may lead to severe and potentially fatal lung problems. These can include difficulty breathing, lung inflammation, lung infections, fluid buildup in the lungs, and other serious lung issues. These problems can happen as a result of reactions to the medication during infusion.

FAQ's

What is Trastuzumab?

Trastuzumab, a monoclonal antibody is used for the treatment of HER2-overexpressing breast cancer and metastatic gastric or gastroesophageal junction adenocarcinoma.

How is Trastuzumab administered? 

Trastuzumab is typically administered intravenously (IV), either alone or in combination with other medicines, over a specific period as directed.

How should I store Trastuzumab?

Store Trastuzumab in the refrigerator between 36°F to 46°F (2°C to 8°C) in its original packaging. Do not freeze.

How much does Trastuzumab cost in India?

Trastuzumab 440 mg cost in India is reasonable and can vary. To procure it legally, you can call us at (+91) 8130290915, TOLL-FREE: 1800-889-1064, Or Write us at info@indiangenericmedicines.com.

Can Trastuzumab be used while I’m pregnant?

Trastuzumab may be unsafe if used during pregnancy. Talk to your doctor about the best way to help control your disease if you want to become pregnant or during pregnancy. 

Can Trastuzumab be used while breastfeeding?

Breastfeeding is not recommended while on Trastuzumab. Talk to your doctor if you are breastfeeding or intend to breastfeed.

Where can I get Trastuzumab at the best Price? 

Order Trastuzumab at the best price today. We request you to Call/WhatsApp us at (+91) 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 or Write us at info@indiangenericmedicines.com. We are fully committed to providing you with the best Trastuzumab price from India. That is why we’ll match the cost/price of any other existing suppliers/distributors in the market who require a medical prescription.

Is Trastuzumab available in India?

Trastuzumab is a (prescription drug, doctor-prescribed medication, or health care professional-prescribed medicine) pharmaceutical drug that can be legally dispensed against a medical prescription. Trastuzumab can be made available through the network of authorized distributors in India. (Mumbai, Ahmedabad, Kolkata, Hyderabad, Bangalore, Chennai, Delhi, Pune, etc.)

Can You Send the Trastuzumab to Foreign Destinations?

Buy Trastuzumab online at the best/lowest price from a leading supplier. Indian Generic Medicines (IGM) can assist in the delivery of Trastuzumab; the doctor-prescribed medication to the UK, Canada, Australia, Philippines, the USA, Saudi Arabia, Thailand, China, South Africa, Kazakhstan, Uzbekistan, Zambia, Turkey, Pakistan, Kuwait, Sweden, Hong Kong, Afghanistan, Malaysia, Singapore, Qatar, Japan, Nepal, Sri Lanka, UAE, and many other countries.

What is the procedure to buy Trastuzumab from Indian Generic Medicines

Patients can fill out the order form or send mail to info@indiangenericmedicines.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008891064. We will reply ASAP with the details of the Trastuzumab 440 mg price and the procurement procedure.

Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy Trastuzumab online from India?

Yes, one can buy Trastuzumab online from India-based Indian Generic Medicines (IGM) if the medicine is not (yet) registered or is unavailable in their home country. We can facilitate the supply of Trastuzumab through legal channels.