Infliximab is a tumor necrosis factor (TNF) blocker used for:
- Psoriatic Arthritis
- Ankylosing Spondylitis
- Rheumatoid Arthritis (RA): adults with moderately to severely active rheumatoid arthritis, along with the medication methotrexate.
- Crohn’s Disease: children aged 6 years and older and adults with Crohn’s disease who have not responded well to other medications.
- Plaque Psoriasis: adult patients with plaque psoriasis that doesn’t go away, severe, extensive, or disabling.
- Ulcerative Colitis (UC): children aged 6 years and older and adults with moderately to severely active UC who have not responded well to other medicines.
Dosage and Side Effects
The recommended dosage of infliximab injection is administered by intravenous infusion over a period of not less than 2 hours.
- Psoriatic Arthritis: The recommended dosage is 5 mg/kg at 0, 2 & 6 weeks, then every 8 weeks.
- Ankylosing Spondylitis: The recommended dosage is 5 mg/kg at 0, 2 & 6 weeks, then every 6 weeks.
- Rheumatoid Arthritis: In conjunction with methotrexate, the recommended dosage is 3 mg/kg at 0, 2 & 6 weeks, then every 8 weeks. Some patients may benefit from increasing the dose up to 10 mg/kg or treating as often as every 4 weeks.
- Crohn’s Disease: The recommended dosage for Pediatric and Adult patients is 5 mg/kg at 0, 2 & 6 weeks, then every 8 weeks. Some adult patients who initially respond to treatment may benefit from increasing the dose to 10 mg/kg in case they later lose their response.
- Plaque Psoriasis: The recommended dosage is 5 mg/kg at 0, 2 & 6 weeks, then every 8 weeks.
Ulcerative Colitis: The recommended dosage for Pediatric and Adult patients is 5 mg/kg at 0, 2 & 6 weeks, then every 8 weeks.
The most commonly reported side effects (>10%) due to infliximab infusion include: infections (e.g. upper respiratory, sinusitis, and pharyngitis), abdominal pain, headache, and infusion-related reactions.
What is Infliximab?
Infliximab is a prescription medication used to treat Crohn’s Disease, Pediatric Crohn’s Disease, Ulcerative Colitis, Pediatric Ulcerative Colitis, Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, and Plaque Psoriasis.
What dosage strengths Infliximab is supplied?
Infliximab is supplied as 100 mg of lyophilized in a 20 mL vial for intravenous infusion.
How is Infliximab administered?
The recommended dosage of Infliximab is administered as intravenous infusion.
What type of medicine is Infliximab?
Infliximab specifically is a medicine named tumor necrosis factor (TNF) blocker.
How much does Infliximab infusion cost?
The infliximab price varies between individuals. The dose of infliximab is adjusted according to a patient’s body weight.The buyer should check the existing law in their home country before importing the product.
What should I avoid while receiving Infliximab?
Do not take Infliximab together with medicines such as ORENCIA (abatacept), KINERET (anakinra), ACTEMRA (tocilizumab), or other medications named biologics that are used to treat the same conditions as Infliximab.