Tocilizumab

  • Medicine- Tocira 
  • API- Tocilizumab
  • Packaging- Single-use vial
  • Strength- 80 mg/4mL, 200 mg/10mL, 400 mg/20mL
  • Manufactured by- Hetero Healthcare Limited
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Description

Tocilizumab Injection is a medicine that helps treat different conditions:

  • Rheumatoid Arthritis (RA):
    • For adults with moderate to severe rheumatoid arthritis.
    • Especially for those who haven’t responded well to other medications for arthritis.
  • Giant Cell Arteritis (GCA):
    • For adults dealing with giant cell arteritis.
  • Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD):
    • It helps slow down the decline in lung function for adults with systemic sclerosis-associated interstitial lung disease.
  • Polyarticular Juvenile Idiopathic Arthritis (PJIA):
    • For kids aged 2 and older with active polyarticular juvenile idiopathic arthritis.
  • Systemic Juvenile Idiopathic Arthritis (SJIA):
    • For kids aged 2 and older with active systemic juvenile idiopathic arthritis.
  • Cytokine Release Syndrome (CRS):
    • For adults and kids aged 2 and older experiencing severe or life-threatening cytokine release syndrome caused by CAR T cell therapy.

In simple terms, Tocilizumab injection helps people with arthritis, lung issues, and certain types of arthritis in children and also supports those experiencing severe reactions to certain therapies.

Dosage and Side Effects

The medication is given in the form of monthly intravenous infusions. An infusion takes around one hour.

Headache, upper respiratory tract infections, nasopharyngitis, hypertension, elevated ALT, and injection site responses are the most prevalent adverse effects.

Warning and Precautions

  • Don’t use this medicine if there’s a current infection or hidden tuberculosis. If a serious infection happens, stop taking tocilizumab until it’s under control. Before starting Tocilizumab injection, check for tuberculosis risk and latent infection.
  • Watch closely for signs of infection while using Tocilizumab 200 mg injection. Be cautious if there’s a higher risk of stomach perforation. It’s not recommended for patients with very low neutrophil count (less than 500 per mm).
  • Check neutrophil levels 4 to 8 weeks after starting and every 3 months. Also, monitor ALT and AST levels during the same periods. The intravenous use of tocilizumab injection should only be done by a healthcare pro to handle any serious reactions.
  • Look out for signs of demyelinating disorders. Avoid this injection if you’re known to be hypersensitive to tocilizumab injection. Stay away from live vaccines, as their safety with this medicine isn’t confirmed.
  • If there’s an overdose, watch for adverse reactions and provide appropriate treatment for any symptoms.

FAQ's

When is Tocilizumab not recommended or contraindicated?

Tocilizumab injection is not recommended in certain situations, such as during active infections, tuberculosis, or if someone has a known hypersensitivity to the medication. Its use may also be cautioned in specific patient groups.

Is Tocilizumab safe during pregnancy or while breastfeeding?

Safety data for Tocilizumab injection during pregnancy and breastfeeding is limited. It’s important to consult a healthcare professional regarding the risks and benefits before using this medication in such situations.

Can Tocilizumab interact with other medications?

Tocilizumab injection may interact with certain drugs, so it’s crucial to inform your doctor about all medications, including prescription, over-the-counter, herbal supplements, and vitamins you are taking.

What is the price of Tocilizumab?

The price of Tocilizumab injection is reasonable and one can find this medicine with certified pharmaceutical suppliers worldwide. To know more about this medicine call us at +91 8130290915 or mail us at info@indiangenericmedicines.com.