Buy Azacitidine 100 mg Injection Online at Lowest Price.

Azacitidine Injection

  • Medicine Name- Xpreza
  • API- Azacitidine
  • Packaging- Single-use vial
  • Strength- 100 mg/vial
  • Manufactured by- Natco Pharma
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Description

Azacitidine is a nucleoside metabolic inhibitor used for the treatment of adult patients with the following FAB myelodysplastic syndrome (MDS) subtypes: Refractory anemia (RA) or refractory anemia with ringed sideroblasts (if case accompanied by neutropenia/thrombocytopenia/requiring transfusions), refractory anemia with excess blasts (RAEB), refractory anemia with excess blasts in transformation (RAEB-T), and chronic myelomonocytic leukemia (CMMoL). 

Xpreza injection is also used for the treatment of pediatric patients aged 1 month and older with newly diagnosed Juvenile Myelomonocytic Leukemia (JMML).

Dosage and Side Effects

MDS: The recommended starting dosage of Azacitidine for the initial treatment cycle, for all patients regardless of baseline hematology values, is 75 mg/m2 daily for 7 days to be administered by either subcutaneous (SC) injection or intravenous (IV) infusion.

JMML: The recommended dosage for pediatric patients with JMML aged 1 month to less than 1 year or weighing less than 10 kg is 2.5 mg/kg, and for patients aged 1 year and older and weighing 10 kg or more is 75 mg/m2 administered as an intravenous (IV) infusion daily for 7 days in a 28-day cycle. Treat patients for a minimum of 3 cycles and a maximum of 6 cycles. 

The most common side effects of Azacitidine injection in adult patients with MDS by the subcutaneous route are nausea, vomiting, anemia, thrombocytopenia, leukopenia, diarrhea, injection site erythema, pyrexia, constipation, neutropenia, and ecchymosis. The most common side effects by intravenous route are weakness, petechiae, rigors, and hypokalemia.

The most common side effects of Azacitidine 100 mg injection by intravenous (IV) route in pediatric patients with JMML are upper respiratory tract infection, pyrexia, rash, and anemia

Warning and Precautions

  • Because of substantial differences in the pharmacokinetic parameters, the recommended dose and schedule for Azacitidine are different from those of oral azacitidine products. Treatment of patients using this drug at the recommended dosage of oral azacitidine may result in fatal side effects. Do not substitute Azacitidine injection for oral azacitidine.
  • Patients with renal impairment may be at higher risk for renal toxicity. Also, the therapeutic drug azacitidine and its metabolites are mainly excreted by the kidney. Therefore, monitor patients closely for potential toxicity. 
  • Azacitidine may cause fatal or critical tumor lysis syndrome (TLS), including in patients with MDS. Tumor lysis syndrome (TLS) may occur despite concomitant use of allopurinol. Assess baseline risk and monitor and treat patients as appropriate.
  • This medicine causes anemia, neutropenia, and thrombocytopenia in adult patients with MDS and in pediatric patients with Juvenile myelomonocytic leukemia. Monitor complete blood counts (CBC) frequently for response or toxicity, at a minimum, before each dosing cycle.
  • Because azacitidine is hepatotoxic in those with serious pre-existing hepatic impairment, caution is required in patients with liver disease.  Azacitidine is not for patients with advanced malignant hepatic tumors. Monitor liver chemistries before initiating treatment and with each cycle.
  • Based on the mechanism of action and outcomes Azacitidine can cause fetal harm if used by a pregnant woman. Females of reproductive potential should use effective contraception during treatment and for 6 months after the final dose.

FAQ's

What is Xpreza?

Xpreza is a generic of Vidaza that contains Azacitidine as the main component. This medicine is used for the treatment of patients with all subtypes of Myelodysplastic Syndrome (MDS) and pediatric patients with newly diagnosed Juvenile Myelomonocytic Leukemia (JMML).

Who has launched the generic Xpreza?

Natco Pharma Ltd has launched the generic Xpreza, as 100 mg/vial injections for either subcutaneous or intravenous use.

How do I store Azacitidine vials?

Store unreconstituted vials of Azacitidine at 25°C (77°F); excursions permitted to 15-30°C (59-86°F).

How much does Azacitidine cost in India?

Azacitidine 100 mg/vial cost in India is very reasonable and can vary. To procure it legally, you can call us at (+91) 8130290915, TOLL-FREE: 1800-889-1064, Or Write us at info@indiangenericmedicines.com.

Where can I get Azacitidine at the best Price? 

Order Azacitidine injection at the best price today. We request you to Call/WhatsApp us at (+91) 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 or Write us at info@indiangenericmedicines.com. We are fully committed to providing you with the best Azacitidine 100 mg injection price in India. That is why we’ll match the cost/price of any facilitators/suppliers/distributors in the market who require a medical prescription.

Is Azacitidine available in India?

Azacitidine injection is a (prescription drug, doctor-prescribed medication, or health care professional-prescribed medicine) pharmaceutical drug that can be legally dispensed against a medical prescription. Azacitidine can be made available through the network of authorized distributors in India. (Mumbai, Ahmedabad, Kolkata, Hyderabad, Chennai, Bangalore, Delhi, Pune, etc.). 

Can You Send the Azacitidine to Foreign Destinations?

Buy generic Azacitidine injection online at the best/lowest price from a leading supplier. Indian Generic Medicines (IGM) can assist in the delivery of Azacitidine; the doctor-prescribed medication to the UK, China, South Africa, Canada, Thailand, Kazakhstan, Australia, Philippines, the USA, Saudi Arabia, Uzbekistan, Zambia, Turkey, Afghanistan, Pakistan, Kuwait, Sri Lanka, Hong Kong, UAE, Malaysia, Sweden, Singapore, Qatar, Japan, Nepal, and many other countries.

What is the procedure for buying Azacitidine from Indian Generic Medicines? 

Patients can just fill out the order form or send mail to info@indiangenericmedicines.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008891064. We will reply ASAP with the details of the Azacitidine 100 mg/vial price and the procurement procedure.

Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy Azacitidine (Xpreza) online from India?

Yes, one can buy Azacitidine (Xpreza) injection online from India-based Indian Generic Medicines if this medicinal product is not (yet) registered or is unavailable in their respective country. We can facilitate the supply of Azacitidine injection through legal channels.

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