API- Flucytosine

Packaging- Strip of 10 Tablets

Strength-  500mg

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Flucytosine specifically is a fluorinated pyrimidine analogue family of medications used for the treatment of severe infections caused by the fungus. It is used together with the other drugs, in order to relieve yeast as well as fungal infections affecting the entire body.

Dosage and Side Effects

Flucytosine 500 mg tablet should be taken in the dose and duration as instructed by your healthcare practitioner. Tablets should be taken with food preferably at a fixed time. In case multiple tablets are required for each dose, they need to be taken over a period of 15 minutes in order to reduce stomach upset.
In an event of drug overdose or missed dose, inform your healthcare practitioner as soon as possible.

Most common adverse reactions include bone marrow suppression, vomiting, diarrhea, psychosis and loss of appetite.

Warning and Precautions

  • Flucytosine 500 mg tablets should be used with extra caution in patients who are with kidney disease. Dose adjustment may be required. Please consult your healthcare practitioner.
  • Patients should be regularly monitored for liver function tests, while taking treatment with flucytosine tablets.
  • Women with childbearing potential should avoid taking treatment with cytorx, as it may be hazardous to the fetus.
  • The cytorx is probably unsafe to use during breastfeeding, so women should avoid breastfeeding while on flucytosine tablets.
  • It is unspecified whether it is safe to consume alcohol with 5 flucytosine tablets. Please consult your healthcare practitioner.


Is Flucytosine an antifungal drug?

Flucytosine is an antifungal drug; fungal organisms take it up via the enzyme cytosine permease.

From which class of drug Flucytosine tablets belongs?

The flucytosine tablets belong to the class of drugs named fluorinated pyrimidine analogue.

What are the ingredients of the medicine Flucytosine?

The active ingredient in the medicine is Flucytosine, and the inactive ingredients are corn starch, lactose and talc.

What are commonly reported side effects of flucytosine?

Bone marrow suppression, loss of appetite, vomiting, diarrhea, and psychosis are the commonly reported side effects.

How should Flucytosine be given?

The recommended dose of Flucytosine should be usually administered by mouth.

How does Flucytosine work?

Falls under the fluorinated pyrimidine analogue family of medications, 5 flucytosine specifically works by being converted into the fluorouracil inside the fungus, which basically impairs its ability in order to make protein.

How much does flucytosine cost?

The average wholesale price for a strip of 10 tablets of Flucytosine (Cytorx) in India is around 1200 INR.