Sofosbuvir

  • Medicine Name- Hepcinat
  • API- Sofosbuvir 
  • Packaging- 28 Tablets
  • Strength- 400mg
  • Manufactured by- Natco Pharma
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Description

Sofosbuvir, a hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitor, is supplied under the generic brand name Hepcinat. This therapeutic drug is widely used for the treatment of:

  • Adults with genotype 1, 2, 3 or 4 chronic HCV (hepatitis C virus) infection without cirrhosis or with compensated cirrhosis as a component of a combination antiviral treatment regimen.
  • Pediatric patients aged 3 years and older with genotype 2/3 chronic (hepatitis C virus) HCV infection without cirrhosis or with compensated cirrhosis in conjunction with ribavirin.

Dosage and Side Effects

The recommended dosage of Sofosbuvir is one 400 mg tablet, taken orally, once daily with or without food. It is taken in combination with ribavirin or in combination with pegylated interferon and ribavirin for treating hepatitis C virus (HCV).

The recommended dose of Sofosbuvir tablets in pediatric patients aged 3 years and older with genotype 2/3 hepatitis C virus (HCV) is based on weight. Patients weighing at least 35 kg should take one 400 mg tablet once daily, patients weighing 17 kg to less than 35 kg should take one 200 mg tablet once daily, and patients weighing less than 17 kg should take 150 mg daily with or without food.

The most common side effects of Sofosbuvir in combination with ribavirin are fatigue and headache, and in combination with medicines peginterferon alfa and ribavirin are fatigue, nausea, headache, insomnia, and anemia.

Warning and Precautions

  • Hepatitis B virus (HBV) reactivation may establish in HCV/HBV coinfected individuals who are undergoing or finished treatment with HCV direct acting antivirals, and who are not receiving HBV antiviral treatment.
  • Test patients for evidence of current or previous HBV infection by measuring HBsAg and anti-HBc prior to starting HCV treatment with Sofosbuvir 400 mg. In those with serologic presence of HBV infection, evaluate for clinical and laboratory signs of hepatitis flare or HBV reactivation during therapy and during post-treatment follow-up. Start useful patient management for HBV infection as clinically required.
  • Patients who are taking Hepcinat who need to begin amiodarone therapy because of no other alternative, viable therapy options should undergo cardiac monitoring. Because of amiodarone’s long half-life, those discontinuing amiodarone just before starting Hepcinat should also undergo cardiac monitoring.
  • Therapeutic drugs that are P-gp inducers in the intestine (such as St. John’s wort and rifampin) may significantly reduce sofosbuvir plasma concentrations and may reduce the therapeutic effect of Sofosbuvir. The use of rifampin and St. John’s wort with Sofosbuvir 400 mg tablets is not recommended.

FAQ's

What is Hepcinat?

Hepcinat is a generic version of Sovaldi. It is a once-daily dosing treatment for patients with chronic HCV. 

Who has launched the generic Hepcinat?

Natco Pharma Ltd has launched the generic Hepcinat for treating hepatitis C virus (HCV).

How do I take Sofosbuvir

Sofosbuvir comes as a 400 mg tablet. The recommended dose is taken orally once daily, with or without food.

How do I store Sofosbuvir?

Store below 30°C (86°F). Dispense it only in the original container. Do not use this medicine if the seal over the bottle opening is broken/missing.

How much does Sofosbuvir cost in India?

Sofosbuvir 400 mg cost in India is very reasonable and can vary. To procure it legally, you can call us at (+91) 8130290915, TOLL-FREE: 1800-889-1064, Or Write us at info@indiangenericmedicines.com.

Can Sofosbuvir be used while I’m pregnant?

Sofosbuvir may be hazardous if used during pregnancy. Talk to your doctor about some other potential ways to control your disease during pregnancy. 

Can Sofosbuvir be used while breastfeeding?

Avoid breastfeeding while on Sofosbuvir treatment. Talk to your doctor if you are breastfeeding or intend to breastfeed.

Where can I get Sofosbuvir at the best Price? 

Order Sofosbuvir at the best price today. We request you to Call/WhatsApp us at (+91) 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 or Write us at info@indiangenericmedicines.com. We’re fully committed to providing you with the best Sofosbuvir 400 mg price from India. That is why we’ll match the cost/price of any other existing suppliers/distributors in the market who require a medical prescription.

Is Sofosbuvir available in India?

Sofosbuvir is a (prescription drug, doctor-prescribed medication, or health care professional-prescribed medicine) pharmaceutical drug that can be legally dispensed against a medical prescription. Sofosbuvir can be made available through the network of authorized distributors in India (Bangalore, Kolkata, Delhi, Mumbai, Ahmedabad, Hyderabad, Chennai, Pune, etc.)

Can You Send the Sofosbuvir to Foreign Destinations?

Buy Sofosbuvir 400 mg online at the best/lowest price from a leading supplier. Indian Generic Medicines (IGM) can assist in the delivery of Sofosbuvir; the doctor-prescribed medicine to the UK, Canada, Kuwait, Thailand, Australia, Saudi Arabia, Philippines, the USA, China, Kazakhstan, South Africa, Uzbekistan, UAE, Afghanistan, Sri Lanka, Zambia, Sweden, Pakistan, Hong Kong, Turkey, Singapore, Malaysia, Qatar, Japan, Nepal, and many other countries.

What is the procedure for buying Sofosbuvir from Indian Generic Medicines

Patients can fill out the order form or send mail to info@indiangenericmedicines.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008891064. We will reply ASAP with the details of the generic sofosbuvir 400 mg price and the procurement procedure.

Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy Sofosbuvir (Hepcinat 400 mg) online from India?

Yes, one can buy Sofosbuvir (Hepcinat 400 mg) online from India-based Indian Generic Medicines (IGM) if it is not (yet) registered or is unavailable in their respective country. We can facilitate the supply/export of Sofosbuvir tablets through legal channels.