Adalimumab 40mg/0.8mL Injection

  • Medicine Name- Exemptia
  • API- Adalimumab
  • Packaging- Single-dose pre-filled syringe
  • Strength- 40mg/0.8mL
  • Manufactured by- Zydus Cadila
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Description

Adalimumab is a fully human, recombinant monoclonal antibody (mAb) with high affinity, and acts as a tumor necrosis factor-alpha (TNF-α) inhibitor. This therapeutic drug is used to treat several autoimmune conditions such as Rheumatoid arthritis (RA), Crohn disease (CD), Ankylosing spondylitis (AS), Ulcerative colitis (UC), Psoriatic arthritis (PsA), Hidradenitis suppurativa (HS), Juvenile idiopathic arthritis (JIA), Plaque psoriasis (Ps), and Uveitis (UV).

Dosage and Side Effects

Rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis:

  • The recommended dosage for these conditions is 40 mg administered subcutaneously every other week.

Juvenile idiopathic arthritis or pediatric uveitis:

  • For patients weighing  from 10 kg to less than 15 kg: 10 mg is administered subcutaneously every other week.

  • For patients weighing from 15 kg to less than 30 kg: 20 mg is administered subcutaneously every other week.

  • For patients weighing more than 30 kg: 40 mg administered subcutaneously every other week.

Adult Crohn’s disease and ulcerative colitis:

  • The initial recommended dosage is administered on day 1: 160 mg.

  • The recommended second dosage is administered 2 weeks after the first dose, on day 15: 80 mg.

  • The third dose is given 2 weeks following the second dose, on day 29: A maintenance dose of 40 mg every other week.

  • For patients with ulcerative colitis (UC) only: Adalimumab needs to be continued solely for those who have shown clinical remission within 8 weeks, on day 57, of therapy.

Plaque psoriasis or adult uveitis:

  • For this condition, an initial recommended dose of 80 mg, followed by 40 mg every other week, commencing 1 week following the initial dose, is recommended. As per findings, adalimumab is suggested as a standalone therapy for moderate-to-severe plaque psoriasis.

Hidradenitis suppurativa:

  • The initial recommended dosage is administered on day 1: 160 mg

  • The second recommended dosage is administered 2 weeks after the first dose, on day 15: 80 mg

  • The third dose is given 2 weeks after the second dose, on day 29, which continues with subsequent doses: 40 mg weekly.

The most common side effects of Adalimumab are infections (e.g. sinusitis, upper respiratory), injection site reactions, rash, and headache.

Warning and Precautions

  • Do not start Adalimumab therapy throughout an active infection. In case an infection develops, monitor precisely, and stop treatment if the infection becomes critical/serious.

  • For individuals who develop a systemic illness on this treatment, consider empiric antifungal therapy for individuals who reside or travel to such regions where mycoses are endemic.

  • Anaphylaxis and angioneurotic edema may occur after Adalimumab 40mg/0.8mL administration. In case an anaphylactic or other critical allergic reaction occurs, promptly stop the administration of Adalimumab and institute relevant therapy.

  • Rare cases of pancytopenia including aplastic anemia may occur with TNF blocking agents. Stop treatment with Adalimumab in individuals with confirmed significant hematologic abnormalities.

  • Cases of worsening congestive heart failure (CHF) and new onset congestive heart failure may occur with TNF blockers. Exercise extreme caution when using this medicine in those who have heart failure and monitor them precisely.

  • Treatment with Adalimumab may cause the formation of autoantibodies and, occasionally, the development of a lupus-like syndrome. If a patient develops a lupus-like syndrome following this treatment, discontinue treatment immediately.

FAQ's

What is Adalimumab?

Adalimumab is a fully human, recombinant monoclonal antibody (mAb) with high affinity and is a tumor necrosis factor-alpha (TNF-α) inhibitor. It is used for treating various autoimmune disorders/conditions.

How do I administer Adalimumab

Administer Adalimumab subcutaneously at distinct sites in the thigh or lower abdomen, avoiding areas within two inches of the navel.

How do I store Adalimumab?

Adalimumab must be refrigerated at 36-46°F (2-8°C). Never freeze it. Avoid using it if it is frozen. Store in original carton until time of use to protect from light. 

How much does Adalimumab cost in India?

Adalimumab cost in India is very reasonable and can vary. To procure this therapeutic drug legally, you can call us at (+91) 8130290915, TOLL-FREE: 1800-889-1064, Or Write us at info@indiangenericmedicines.com.

Can Adalimumab be used while I’m pregnant?

Adalimumab may be unsafe if used during pregnancy. Take advice from your doctor about the best way to manage your disease if you want to become pregnant or during pregnancy. 

Can Adalimumab be used while breastfeeding?

Breastfeeding is not recommended while on Adalimumab. Take advice from your doctor in case you are breastfeeding or intend/want to breastfeed.

Where can I get Adalimumab at the best Price? 

Order Adalimumab at the best price today. We request you to Call/WhatsApp us at (+91) 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 or Write us at info@indiangenericmedicines.com. We are fully committed to providing you with the best Adalimumab price from India. That is why we’ll match the cost/price of any other existing suppliers/distributors in the market who require a medical prescription.

Is Adalimumab available in India?

Adalimumab is a (prescription drug, doctor-prescribed medicine, or health care professional-prescribed medication) pharmaceutical drug that can be legally dispensed against a medical prescription. Adalimumab can be made available through the network of authorized distributors in India. (Mumbai, Chennai, Delhi, Ahmedabad, Kolkata, Hyderabad, Bangalore, Pune, etc.)

Can You Send the Adalimumab to Foreign Destinations?

Buy Adalimumab 40mg/0.8mL online at the best/lowest price from a leading supplier. Indian Generic Medicines can assist in the delivery of Adalimumab; the doctor-prescribed medication to the UK, Saudi Arabia, Canada, Australia, Sri Lanka, Philippines, the USA, Thailand, China, Kazakhstan, Uzbekistan, UAE, Zambia, South Africa, Pakistan, Kuwait, Sweden, Turkey, Afghanistan, Malaysia, Singapore, Qatar, Japan, Nepal, Hong Kong, and many other countries.

What is the procedure to buy Adalimumab from Indian Generic Medicines

Patients can fill out the order form or send mail to info@indiangenericmedicines.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008891064. We will reply ASAP with the details of the Adalimumab 40mg/0.8mL price and the procurement procedure.

Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy Adalimumab online from India?

Yes, one can buy Adalimumab online from India-based Indian Generic Medicines if this medicine is not (yet) registered or is unavailable in their respective country. We can help facilitate the supply/export of Adalimumab through legal channels.