Prednisolone

  • Medicine- Omnacortil
  • API- Prednisolone
  • Packaging- Strips
  • Strength- 10 mg, 15 mg, 30 mg
  • Manufactured by- Macleods Pharmaceuticals Pvt. Ltd.
Get an Enquiry

Description

The corticosteroid Prednisolone Tablet is used in:

  • For certain allergy, gastrointestinal, dermatologic, hematologic, ophthalmologic, neurological system, renal, pulmonary, rheumatologic, certain infectious diseases or disorders, and organ transplantation as an anti-inflammatory or immunosuppressive medication.
  • For the management of specific endocrine disorders.
  • In order to alleviate specific neoplastic diseases.

Dosage and Side Effects

Prednisolone tablet dosage should be customized based on the patient’s response and the severity of the illness. The same factors should apply to standard dosage for pediatric patients rather than rigidly adhering to the body weight or age-based ratio.

Initial Dosage: The starting dose of Prednisolone typically ranges from 10-60 mg (equivalent to 13.4-80.6 mg of prednisolone sodium phosphate) per day, varying based on the specific illness being treated.

Maintenance Dosage: Once an effective response is achieved, a lower maintenance dosage of Prednisolone is used. If discontinuing after long-term or high-dose therapy, it’s important to taper off gradually.

Prednisolone 10 mg tablets come in blister packaging. It’s advised not to remove the tablet until just before taking it. Open the blister pack carefully, place the disintegrating tablet on the tongue to dissolve in the mouth, and swallow without breaking or splitting. To minimize gastrointestinal irritation, take the tablets with meals.

Common side effects associated with Prednisolone include weight gain, changes in glucose tolerance, fluid retention, increased blood pressure, alterations in behavior and mood, and heightened appetite.

Warning and Precautions

  • Corticosteroids may lead to increased blood pressure, retention of salt and water, and higher excretion of calcium and potassium. Some patients might require dietary changes like salt restriction or potassium supplements. Caution is advised when using these medications in individuals with congestive heart failure, hypertension, or kidney problems.
  • There’s a risk of gastrointestinal perforation in patients with certain digestive tract conditions. Symptoms of such perforation might be hidden in individuals taking corticosteroids. These agents should be used cautiously in cases where there’s a potential for gastrointestinal issues like impending perforation, abscess, pyogenic infections, recent intestinal surgery, diverticulitis, or active or latent peptic ulcers.
  • The use of prednisolone might affect the central nervous system, leading to various effects such as mood swings, euphoria, insomnia, personality changes, severe depression, or even psychotic symptoms. Patients with existing emotional instability or psychotic tendencies might experience aggravated symptoms when using this medication.
  • Corticosteroids can impact bone health by reducing bone formation and increasing bone breakdown, posing a risk of osteoporosis, especially in individuals at higher risk like postmenopausal women. Monitoring bone density is recommended for patients on long-term corticosteroid therapy.
  • Patients with ocular herpes simplex should use corticosteroids cautiously due to the risk of corneal perforation. It’s crucial not to use corticosteroids in cases of active ocular herpes simplex.
  • Immunosuppressive doses of corticosteroids can interfere with the effectiveness of live vaccines. Killed or inactivated vaccines may be administered, but the response to such vaccines might not be predictable.
  • Avoid administering smallpox vaccinations to patients on corticosteroid therapy. Additionally, other immunization procedures in individuals, especially those on high doses of corticosteroids, should be approached cautiously due to potential neurological complications and an inadequate antibody response.
  • Long-term use of prednisolone at 10 mg doses might negatively impact the growth and development of children. It’s crucial to closely monitor the growth and development of pediatric patients undergoing prolonged prednisolone therapy.
  • Using Prednisolone 15 mg during pregnancy can harm the fetus. Studies indicate an increased risk of orofacial clefts, intrauterine growth restriction, and decreased birth weight when this medication is used during the first trimester of pregnancy.

FAQ's

What is Prednisolone used for?

Prednisolone is a steroid commonly prescribed to treat various allergies, inflammatory conditions, autoimmune diseases, and certain types of cancer.

What strengths are available for Prednisolone Orally Disintegrating Tablet?

Prednisolone Orally Disintegrating Tablets are available in three strengths:

  • Prednisolone 10 mg orally disintegrating tablet
  • Prednisolone 15 mg orally disintegrating tablet
  • Prednisolone 30 mg orally disintegrating tablet

How is Prednisolone administered?

Prednisolone is typically provided in the form of orally disintegrating tablets meant for oral consumption.

What category of medication does Prednisolone belong to?

Prednisolone falls under the category of medications known as corticosteroids.

Where can I purchase Prednisolone Tablets?

You can obtain Prednisolone Tablets from authorized wholesalers upon presenting a valid prescription from a qualified physician. It’s advisable to verify the credentials of the wholesaler, supplier, or exporter before making a purchase.

Before importing the product, buyers should familiarize themselves with the existing laws and regulations in their home country regarding such purchases.