Ceritinib

  • Medicine Name- Noxalk
  • API- Ceritinib
  • Packaging- 30/90 Capsules
  • Strength- 150 mg 
  • Manufactured by- Natco Pharma
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Description

Ceritinib Capsule is supplied under the generic brand Noxalk and in the form of oral capsules. Ceritinib 150 mg Capsules is a kinase inhibitor used for the treatment of adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are anaplastic lymphoma kinase (ALK)-positive.

Dosage and Side Effects

The recommended dosage of Ceritinib capsule is 450 mg orally (by mouth) once daily with food until the disease progresses or unacceptable toxicity occurs. If a dose is missed, make up that dose unless the next dose is due within at least 12 hours. If vomiting occurs during the course of therapy, do not take an additional dose and continue with the very next scheduled dose of Ceritinib.

The most common side effects of Ceritinib 450 mg with food are abdominal pain, diarrhea, nausea, vomiting, and fatigue; and with Ceritinib 750 mg under fasted conditions: diarrhea, nausea, vomiting, fatigue, weight loss, abdominal pain, and decreased appetite.

Warning and Precautions

  • Serious gastrointestinal side effects may occur in patients treated with Ceritinib 750 mg under fasted conditions. Monitor and manage patients using standard of care, including antiemetics, antidiarrheals, or fluid replacement, as required. Withhold this therapy if a gastrointestinal side effect is critical or not tolerable and is not responsive to antidiarrheals or antiemetics.
  • Drug-induced hepatotoxicity may develop in patients treated with Ceritinib. Monitor with liver laboratory tests, including AST, ALT, and total bilirubin, monthly and as clinically required, with more periodic testing in those who develop transaminase elevations. Based on the severity of the side effects, withhold treatment with resumption at a decreased dose, or permanently stop treatment.
  • Severe, critical, or fatal interstitial lung diseases (ILD)/pneumonitis may occur in patients treated with Ceritinib capsules. Monitor patients for ILD/pneumonitis. Exclude other probable causes of ILD or pneumonitis and permanently stop treatment in those diagnosed with treatment-related ILD or pneumonitis.
  • Hyperglycemia may be established in patients treated with Zykadia 150 mg capsules. Monitor fasting serum glucose before the start of the treatment and periodically thereafter as clinically needed. Start or optimize anti-hyperglycemic medicines as required.
  • Bradycardia may occur in patients treated with Ceritinib. Avoid using this drug in combination with other products known to cause bradycardia (such as beta-blockers, nondihydropyridine calcium channel blockers, digoxin, and clonidine) to the extent possible. Monitor heart rate as well as blood pressure on a regular basis.
  • Pancreatitis may develop in patients treated with Ceritinib 150 mg capsules. Monitor lipase and amylase before the start of treatment and periodically thereafter as clinically required. Based on the seriousness of the laboratory abnormalities, withhold therapy with resumption at a reduced dose.

FAQ's

What is Ceritinib (Noxalk)?

Ceritinib (Noxalk) is a targeted therapy known as tyrosine kinase inhibitor (TK) used for the treatment and management of non-small cell lung cancer (NSCLC).

Who has launched generic Ceritinib?

Natco Pharma has launched generic Ceritinib capsules at reasonable prices under the brand Noxalk. 

How do I take Ceritinib? 

Take this medicinal product by mouth with a glass of water and food as directed by your doctor. Don’t take this medicine with grapefruit juice. 

How do I store Ceritinib?

Store the capsules of Ceritinib at 20-25°C (68-77°F); excursions permitted between 15-30°C (59-86°F). 

How much does generic Ceritinib cost in India?

Generic ceritinib 150 mg cost in India is very reasonable and can vary. To procure it legally, you can call us at (+91) 8130290915, TOLL-FREE: 1800-889-1064, Or Write us at info@indiangenericmedicines.com.

Can Ceritinib be used while I’m pregnant?

The use of ceritinib capsules during pregnancy may be unsafe. Talk to your doctor about the other right ways to manage your disease if you intend to become pregnant or during pregnancy. 

Can Ceritinib be used while breastfeeding?

Breastfeeding is not advised during treatment with Ceritinib. Call your doctor if you are breastfeeding or intend to breastfeed.

Where can I get Ceritinib at the best Price? 

Order generic ceritinib at the best price today. We request you to Call/WhatsApp us at (+91) 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 or Write us at info@indiangenericmedicines.com. We’re committed to providing you with the best Ceritinib 150 mg price from India. That is why we’ll match the cost/price of any other existing facilitators/suppliers/distributors in the market who require a medical prescription.

Is Ceritinib available in India?

Ceritinib is a (prescription drug, doctor-prescribed medication, or health care professional-prescribed medicine) pharmaceutical drug that can be legally dispensed against a medical prescription. Ceritinib can be made available through the network of authorized distributors in India. (Mumbai, Pune, Ahmedabad, Kolkata, Chennai, Hyderabad, Bangalore, Delhi, etc.)

Can You Send the Ceritinib to Foreign Destinations?

Buy generic ceritinib online at the best/lowest price from a leading supplier. Indian Generic Medicines can assist in the delivery of Ceritinib; the doctor-prescribed medication to the UK, Singapore, Australia, Sri Lanka, Philippines, the USA, UAE, Saudi Arabia, Thailand, China, South Africa, Kazakhstan, Hong Kong, Uzbekistan, Zambia, Canada, Kuwait, Turkey, Afghanistan, Malaysia, Qatar, Japan, Nepal, Pakistan, Sweden, and many other countries.

What is the procedure to buy Ceritinib from Indian Generic Medicines

Patients can fill out the order form or send mail to info@indiangenericmedicines.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008891064. We will reply ASAP with the details of the Ceritinib 150 mg price and procurement procedure.

Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy Ceritinib (Noxalk) online from India?

Yes, one can buy Ceritinib (Noxalk) online from India-based Indian Generic Medicines (IGM) if this drug is not (yet) registered or is unavailable in their respective country. We can help facilitate the supply/export of generic Ceritinib through legal channels.