• Medicine Name- Hamsyl
  • API- Pegaspargase
  • Packaging- Single vial for injection
  • Strength- 3750 IU/5ml (750 IU/ml)
  • Manufactured by- Emcure Pharma
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Pegaspargase Injection, supplied under the brand name Hamsyl (one of the leading generics of pegaspargase Injection) is a modified version of the enzyme L-asparaginase. Pegaspargase Injection is used as a component of a multi-agent chemotherapeutic regimen for the treatment of patients (pediatric and adults) with:

    • First-line acute lymphoblastic leukemia (ALL), and
    • Acute lymphoblastic leukemia (ALL) and hypersensitivity to asparaginase

Dosage and Side Effects

The recommended dosage of Pegaspargase for patients up to and including age 21 years is 2,500 IU/m2 and for adult patients more than 21 years of age is 2,000 IU/m2 intramuscularly (IM) or intravenously (IV) no more often than every 14 days. 

Premedicate patients with acetaminophen, an H-1 receptor blocker (diphenhydramine), and an H-2 receptor blocker (famotidine) 30 to 60 minutes before the administration of Pegaspargase to reduce the risk and severity of infusion and hypersensitivity reactions 

The most common side effects of Pegaspargase may include elevated transaminase, hypoalbuminemia, febrile neutropenia, hyperglycemia, bilirubin increased, pancreatitis, abnormal clotting studies, embolic and thrombotic events, hypertriglyceridemia, and hypersensitivity.

Warning and Precautions

  • Anaphylaxis and severe hypersensitivity reactions may occur in patients receiving this medicine. Premedicate patients 30 to 60 minutes before the administration of the drug. Observe patients for 60 minutes after therapy in a setting with resuscitation equipment and other agents crucial to treating anaphylaxis.
  • Severe thrombotic events, including sagittal sinus thrombosis, may occur in patients receiving Pegaspargase. Discontinue this treatment in patients with severe thrombotic events.
  • Pancreatitis may occur in those receiving this therapy. Hemorrhagic or necrotizing pancreatitis with fatal outcomes may develop. Assess serum amylase or lipase levels to confirm initial signs of pancreatic inflammation. Discontinue therapy if pancreatitis is suspected.
  • Glucose intolerance can develop in patients receiving Pegaspargase 3750 IU/5ml (750 IU/ml). In some instances, glucose intolerance is irreversible. Monitor patients closely for serum glucose.
  • Cases of increased prothrombin time (PT), increased partial thromboplastin time (PPT), and hypofibrinogenemia can occur in patients receiving Hamsyl. Assess patients with the symptoms of hemorrhage with coagulation parameters including PT, PTT, and fibrinogen.
  • Hepatotoxicity and abnormal liver function, including bilirubin (direct and indirect), increased transaminase, reduced serum albumin, and plasma fibrinogen may occur. Evaluate bilirubin and transaminases at least weekly during cycles of therapy that include Hamsyl through at least six weeks after the last final of Hamsyl.


What is Hamsyl?

Hamsyl is a generic of Oncaspar that contains Pegaspargase as the main component. This medication is used for the treatment of acute lymphoblastic leukemia (ALL).

Who has launched the generic of Hamsyl?

Gennova (a subsidiary of Emcure) launched a generic/biosimilar pegaspargase under the brand Hamsyl as a single vial of 3750 IU/5ml (750 IU/ml).

How do I take Pegaspargase

Take pegaspargase as an injection into a muscle (IM or intramuscular) or as a drip into your bloodstream (IV or intravenously).

How do I store Pegaspargase?

Store pegaspargase vials refrigerated at 2-8°C (36-46°F) in the original carton to protect them from the light. Do not shake or freeze it. Unopened vials may be stored at room temperature (15-25°C [59-77°F]) for no more than 48 hours. 

How much does Pegaspargase cost in India?

Pegaspargase cost in India is very reasonable and can vary. To procure it legally, you can call us at (+91) 8130290915, TOLL-FREE: 1800-889-1064, Or Write us at

Where can I get Pegaspargase at the best Price? 

Order pegaspargase at the best price today. We request you to Call/WhatsApp us at (+91) 8130290915 or dial our TOLL-FREE Number: 1800-889-1064 or Write us at We’re fully committed to providing you with the best pegaspargase price from India. That is why we’ll match the cost/price of any other existing facilitators/suppliers/distributors in the market who require a valid medical prescription.

Is the Pegaspargase available in India?

Pegaspargase is a (prescription drug, doctor-prescribed medicine, or health care professional-prescribed medication) pharmaceutical drug that can be legally dispensed against a medical prescription. It can be made available through the network of authorized distributors in India. (Kolkata, Mumbai, Ahmedabad, Chennai, Hyderabad, Bangalore, Delhi, Pune, etc.)

Can You Send the Pegaspargase to Foreign Destinations?

Buy generic pegaspargase online at the lowest price from a leading supplier. Indian Generic Medicines (IGM) can assist in the delivery of Pegaspargase; the doctor-prescribed medication to the UK, Canada, the USA, Australia, Philippines, Saudi Arabia, China, Thailand, Kazakhstan, Uzbekistan, Pakistan, South Africa, Kuwait, Zambia, Sri Lanka, Afghanistan, Sweden, Hong Kong, UAE, Turkey, Singapore, Malaysia, Japan, Qatar, Nepal, and many other countries.

What is the procedure for buying Pegaspargase from Indian Generic Medicines

Patients can fill out the order form or send mail to Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008891064. We will reply ASAP with the details of the Pegaspargase 3750 IU/5ml) price and the procurement procedure.

Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy Pegaspargase (Hamsyl) online from India?

Yes, one can buy pegaspargase (Hamsyl 3750 IU/5ml) online from India-based Indian Generic Medicines (IGM) if this medicine is not (yet) registered or is unavailable in their respective country. We can facilitate the supply/export of generic Pegaspargase through legal channels.