Cyclophosphamide Injection

  • Medicine name- Endoxan
  • API- Cyclophosphamide
  • Pack Size- 1 Single-dose vial
  • Strength- 500 mg
  • Manufactured By: Zydus Cadila
Get an Enquiry


Cyclophosphamide 500 mg Injection is also known as cytophosphane is used as chemotherapy (used in lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma), It is also used as an immune suppressor.

Dosage and Side Effects

The recommended cyclophosphamide dose should be administered by injection into a vein, at the same time every day. Your doctor will determine what dose is appropriate and how often you require to take it.

Most common adverse reactions include fever, neutropenia, alopecia, nausea, vomiting, diarrhea and febrile neutropenia.

Warning and Precautions

  • Patients with cyclophosphamide uses should be monitored for signs and symptoms of pulmonary toxicity.
  • The use of cyclophosphamide should be avoided in patients with urinary outflow obstruction.
  • Patients with cyclophosphamide 500 mg injection should be checked regularly for urinary sediment for the presence of erythrocytes and other signs of nephrotoxicity.
  • Patients with Endoxan N should be monitored for the complete blood counts during treatment so that the dose can be adjusted if required.
  • Pregnancy needs to be avoided during cyclophosphamide injection 500 mg therapy because of the risk of fetal harm.
  • Nursing should be discontinued prior to initiating cyclophosphamide 500 mg treatment.


Is Cyclophosphamide a chemo drug?

Cyclophosphamide is a synthetic antineoplastic (chemotherapy) drug.

What are the alternate brands of Cyclophosphamide Injection?

  • Cycloxan 500mg Injection (Cadila Healthcare Ltd)

  • Chophos 500mg Injection (Intas Pharmaceuticals Ltd) 

  • Phosmid 500mg Injection (Neon Laboratories Ltd) 

  • Cyclocel 500Mg Injection (Celon Laboratories Ltd)

What are the ingredients of the medicine Cyclophosphamide?

The active ingredient in the medicine is Cyclophosphamide, and the inactive ingredient is mannitol.

From which class of drug Cyclophosphamide belongs?

Cyclophosphamide specifically belongs to the class of drugs named alkylating agents.

How should Cyclophosphamide be administered?

The recommended dose of cyclophosphamide injection should be administered by injection into a vein.

How does Cyclophosphamide work?

Falls under the alkylating agent and nitrogen mustard family of drugs, cyclophosphamide is believed to work in order to interfere with the duplication of the DNA and creation of RNA.