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Triokris™ (Trientine 250 mg Capsules)

Original price was: ₹19,500.00.Current price is: ₹14,000.00.

  • Brand Name: Triokris
  • API: Trientine Hydrochloride USP
  • Packaging: 100 Capsules per Bottle
  • Strength: 250 mg
  • Manufacturer: Ikris Pharma Network Pvt. Ltd. (Manufactured in a US FDA–approved facility)
  • Therapeutic Area: Wilson’s Disease
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Description

Introduction to Trientine Hydrochloride 250mg Capsules

Uses of Medicine: Trientine Hydrochloride 250 mg (Brand Name: Triokris) is a copper-chelating agent used primarily to treat patients with Wilson’s disease who cannot take the medicine known as penicillamine. International Importers, Distributors, Wholesalers, NGOs, and Government Tenders can buy Trientine Hydrochloride Capsules online from India through Indian Generic Medicines (a trusted Trientine Supplier & Exporter in India) for the management and treatment of Wilson`s Disease.

Wilson’s disease is a genetic condition that causes an accumulation of excess copper in the liver, brain, and other organs, which can lead to serious health problems. This medicine is manufactured in a US FDA–approved facility for the treatment of:

Wilson’s disease is a condition where the body stores too much copper. Unlike penicillamine, Trientine 250 mg is not recommended to treat cystinuria or rheumatoid arthritis (RA) because it is not effective in these conditions.

Trientine Hydrochloride 250 mg mainly works by attaching to copper in the body, allowing it to be removed in the urine instead, helping to lower copper levels. It may also attach to copper in the gut and reduce the amount taken into the body. It is not advisable to take this therapeutic drug if you are allergic to Trientine or any other ingredients in this medicinal product. Trientine Hydrochloride 250 mg capsule may also reduce the iron level in the blood; you may be prescribed iron supplements. Let your physician know if you have kidney or liver complications, breathing complications, dermatitis (red and itchy skin), or anemia, if you are pregnant or want to breastfeed.

Let your healthcare provider know about all the therapeutic drugs you take, including prescription medicines, over-the-counter medicines, nutritional and vitamin supplements, and herbal medicinal products. Certain medicines may interact with Trientine Hydrochloride 250 mg capsule and reduce its effectiveness by causing undesirable side effects.

Which countries import Triokris (Trientine) from India?

Indian Generic Medicines (IGM) is a trusted Triokris - Trientine Hydrochloride exporter from India. IGM exports to multiple regulated and semi-regulated markets, based on local country regulations and valid prescriptions or institutional requirements. This includes several Latin American countries such as Brazil, Mexico, Colombia, Chile, Argentina, Peru, Ecuador, Costa Rica, Uruguay, Paraguay, Panama, Guatemala, Honduras, Dominican Republic, El Salvador, Bolivia, and Nicaragua. In the Gulf and wider Middle East region, supply can be facilitated to the United Arab Emirates (UAE), Saudi Arabia, Qatar, Kuwait, Bahrain, Oman, Jordan, Lebanon, Iraq, and Yemen through compliant pharma export channels, supported by WHO-GDP–certified logistics, temperature-controlled handling, and full regulatory documentation. Availability is always subject to local regulatory approvals and import norms.

How can I buy Triokris (Trientine) from India?

To buy Triokris (Trientine 250mg) from India through Indian Generic Medicines (IGM), patients, hospitals, importers, wholesalers, and licensed distributors can share their requirement details along with a valid prescription or import license. IGM coordinates sourcing from the manufacturer, manages export documentation, and arranges temperature-appropriate logistics where required. We can supply both single-unit orders and bulk quantities, depending on the buyer’s needs. International buyers are supported with compliant paperwork, including commercial invoices, COA, packing list, and other regulatory documents as per the destination country’s requirements. For buyers evaluating Trientine 250 mg price in India, IGM offers transparent, competitive pricing along with regulatory guidance for global shipments.

How is Triokris (Trientine) used in the treatment of Wilson’s disease?

Triokris (Trientine Hydrochloride Capsules 250 mg) is used as a copper-chelating agent in the management of Wilson’s disease, particularly in patients who are intolerant to D-Penicillamine or require an alternative chelation strategy. Under physician supervision, Trientine binds to excess copper in the body and promotes its excretion via urine, helping to reduce copper accumulation in the liver, brain, and other organs. It is generally given as a long-term therapy, with the daily dose divided into multiple administrations on an empty stomach. Dose selection, duration of therapy, and monitoring (liver function, blood counts, copper parameters) must always be guided by a specialist experienced in managing Wilson’s disease.

Dosage & Side Effects

The recommended dosage of Trientine Hydrochloride for adults and adolescents typically ranges between 750 mg and 1500 mg/day, administered in two to four divided doses. The medicine is taken on an empty stomach, at least one hour before or two hours after meals, to optimize absorption. Avoid the concomitant use with iron, zinc, calcium, or magnesium supplements, as these may interfere with drug absorption. Dosage adjustments must be made under medical supervision, depending on clinical response, laboratory monitoring, and individual patient requirements. Therapy should always be started and managed by a qualified healthcare professional.

The most commonly reported side effects of Trientine Hydrochloride 250 capsules are abdominal pain, change of bowel movements, rash, alopecia, mood swings, difficulty in moving, muscle pain, iron deficiency anemia, and hypersensitivity skin reactions.

Warning and Precautions

  • Do not use Trientine Capsules if you are allergic to this medicine or any other components. Continuous medical supervision is required throughout treatment to ensure safety, monitor for side effects, and manage copper levels effectively in those with Wilson’s Disease.
  • Constant medical oversight during therapy is critical. Regular blood tests are needed to monitor free copper concentration, iron levels, and overall treatment response, particularly in women, to avoid iron deficiency anemia and ensure safe, effective disease management.
  • Trientine Capsule acts as a chelating agent that may reduce serum iron levels. In some cases, iron supplementation becomes necessary. When taking oral iron, it should be administered separately—at least two hours apart—to prevent interference with Trientine absorption and activity.
  • Concurrent use of Trientine Capsules with zinc is not recommended due to insufficient clinical data on their combined safety and dosage. Limited research prevents establishing appropriate dosage guidelines; therefore, physicians typically advise avoiding simultaneous administration to maintain consistent therapeutic efficacy.
  • Patients who previously received D-Penicillamine have reported lupus-like symptoms after switching to Trientine 250 mg Capsules. However, a direct cause-and-effect relationship remains unclear. Physicians should monitor such patients closely during early therapy to detect any immune-related complications.
  • For patients with hepatic or renal impairment, consistent monitoring is important during treatment with Trientine (Tryprine). Regular assessment of liver enzymes, kidney function, and copper balance helps maintain treatment safety and optimize dosage while preventing potential toxicity or metabolic complications.

FAQ's

What is Trientine Hydrochloride Capsule?

Trientine Hydrochloride is a copper-chelating medicine. It is used in the treatment of Wilson’s disease, a genetic disorder caused by mutations in the ATP7B gene. This medicine helps remove excess copper from the body, preventing liver and neurological damage. Manufactured in US FDA-approved plants, it ensures global quality.

How are Trientine Hydrochloride 250 mg capsules administered?

Trientine 250 mg capsules are taken orally on an empty stomach, at least one hour before or two hours after meals. Swallow the capsule whole with water. Do not take it with iron, zinc, calcium, or magnesium supplements, as they interfere with absorption. Follow the physician’s instructions.

How should I store Trientine Hydrochloride 250 mg Capsules?

Trientine hydrochloride capsules should be kept at 25°C and shielded from heat, moisture, and sunlight. It is acceptable to make brief temperature changes between 15°C and 30°C. The medicine should always be kept out of children’s reach and securely closed. Its quality is preserved, and consistent therapeutic efficacy is guaranteed with proper storage.

How much do Trientine Hydrochloride 250 mg Capsules cost in India?

The Trientine 250 mg price in India varies by supplier and brand. Indian Generic Medicines (IGM) offers Triokris, a high-quality generic Trientine manufactured in a US FDA-approved facility, at affordable global prices. For updated costs, contact via Call: +91 85272 73611, WhatsApp: +91 98104 69557, or dial TOLL-FREE: 1800 1200 365.

Where can I get Trientine Hydrochloride 250 mg Capsules at the best price?

Buy Generic Trientine from India through Indian Generic Medicines (IGM), a trusted exporter and supplier of Trientine for global hospitals, importers, and NGOs. We offer cost-effective, verified, and compliant supply options for Wilson’s disease treatment. Contact us today for the best Trientine price in India.

Are Trientine Hydrochloride 250 mg Capsules available in India?

Yes, Trientine Hydrochloride Capsules are available in India through Indian Generic Medicines (IGM) under the brand Triokris. It’s legally supplied through CDSCO-approved channels and exported worldwide. Manufactured in US FDA-approved plants, it ensures global safety and therapeutic effectiveness for Wilson’s disease patients.

Can you send Generic Trientine Hydrochloride 250 mg Capsules to foreign destinations?

Yes, Indian Generic Medicines (IGM) exports Trientine Hydrochloride Capsules globally, including the USA, UK, UAE, Australia, Canada, Germany, and Africa. Our WHO-GDP and EU-GDP–compliant logistics ensure safe, temperature-controlled delivery. Importers, wholesalers, NGOs, hospitals, and distributors can legally source Trientine from India through transparent documentation.

What is the procedure for buying Trientine Hydrochloride 250 mg Capsules from India?

To buy Trientine Hydrochloride Capsules from India, contact Indian Generic Medicines (IGM) via email at info@indiangenericmedicines.com, Call: +91 85272 73611, or WhatsApp: +91 98104 69557. A valid prescription is required for order confirmation. We assist importers, hospitals, and NGOs in legal, compliant procurement and global medicine supply.

Is it safe to buy Trientine Hydrochloride 250 mg Capsules online from India?

Yes, buying Generic Trientine from India through Indian Generic Medicines (IGM) is completely safe and compliant. We are an authorized Trientine supplier & manufacturer in India. The medicine is manufactured in US FDA-approved facilities, ensuring authenticity, quality assurance, and legal export under WHO-GDP and CDSCO regulations.