Cisatracurium Besylate

  • Medicine Name– Cisatra
  • API– Cisatracurium Besylate
  • Packaging– Single-Dose Vial
  • Strength– 10 mg/5mL & 20 mg/10mL
  • Manufactured by– Themis Medicare Ltd
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Description

Cisatra (Cisatracurium Besylate injection) is a medication used during surgeries and in intensive care units (ICU). It is a nondepolarizing neuromuscular blocker, which means it relaxes the muscles without causing initial muscle contractions.

In adults and children aged 1 month to 12 years, Cisatra is used alongside general anesthesia to make it easier to insert a breathing tube (tracheal intubation). It helps ensure that the airway stays open during surgery or other procedures requiring anesthesia.

For adults and children aged 2 to 12 years, Cisatra also provides muscle relaxation during surgery. This is crucial for the surgeon to operate smoothly and safely. The therapeutic drug can be administered as a single dose (bolus) or as a continuous infusion to maintain muscle relaxation throughout the procedure.

In the ICU, Cisatracurium Besylate injection is used for adults who need mechanical ventilation (breathing support). By relaxing the muscles, it helps the ventilator work more effectively, ensuring that the patient receives adequate breathing support.

Due to its specific action, Cisatracurium Besylate injection is carefully dosed and monitored by healthcare professionals to ensure the patient’s safety and the effectiveness of the procedure.

Dosage and Side Effects

Cisatra (Cisatracurium Besylate) is a neuromuscular blocking agent typically used during surgery. The recommended initial dose for adults is 0.15 to 0.2 mg/kg administered intravenously. This dose generally provides 45 to 60 minutes of muscle relaxation. For maintenance, additional doses of 0.03 mg/kg can be given as needed. In critically ill patients or those with kidney or liver impairment, dosing may require adjustment. Always follow the guidance of a healthcare professional (HCP) for individualized dosing and monitor the patient’s response closely during administration.

The most commonly reported side effects of Cisatra (Cisatracurium Besylate) injection are bradycardia, rash, hypotension, flushing, and bronchospasm.

Warning and Precautions

  • Treatment with Cisatra 10 mg/5mL or 20 mg/10mL injection can cause residual muscle paralysis after surgery. Ensure proper monitoring and support until full muscle function is restored. Use a peripheral nerve stimulator to monitor recovery.
  • Cisatracurium may increase the risk of seizures, especially in patients with a history of epilepsy. Monitor for signs of seizures and be cautious when administering to susceptible individuals.
  • Severe allergic reactions, including anaphylaxis, can occur with Cisatracurium. Be prepared to treat anaphylaxis immediately. Discontinue Cisatracurium if any signs of hypersensitivity appear.
  • Medication errors with Cisatracurium can be fatal. Double-check the dosage and ensure it is administered correctly. Use the correct concentration and formulation to avoid errors.
  • Inadequate anesthesia while using generic Cisatracurium can result in patient awareness during surgery, leading to distress and psychological trauma. Ensure sufficient anesthesia is administered before and during its use.
  • There is a potential risk of infection if aseptic techniques are not followed during the preparation and administration of Cisatracurium. Use sterile equipment and techniques to minimize this risk.
  • Cisatracurium’s effects can be potentiated by certain medications, such as antibiotics or inhalation anesthetics, leading to prolonged paralysis. Monitor the patient closely and adjust the dosage as needed.
  • Although rare, Cisatracurium 10 mg/5mL injection can trigger malignant hyperthermia, a life-threatening condition. Monitor for early signs such as increased carbon dioxide production, muscle rigidity, and hyperthermia. Immediate treatment with dantrolene and supportive measures is essential if malignant hyperthermia occurs.

FAQ's

What is Cisatra?

Cisatra is an Indian generic brand that contains Cisatracurium Besylate as an active pharmaceutical ingredient (API). It is an intermediate-acting, non-depolarizing neuromuscular blocking drug used with general anesthesia to help with tracheal intubation and provide muscle relaxation during surgery. It is used in adults and children aged 1 month to 12 years for intubation and in patients aged 2 and older for muscle relaxation during surgery or mechanical ventilation in the ICU.

How is Cisatra (Cisatracurium Besylate) administered?

Cisatra (Cisatracurium Besylate) is administered intravenously, typically as a bolus injection or continuous infusion in a hospital setting.

How do I store Cisatra (Cisatracurium Besylate)?

Refrigerate the vials of Cisatracurium at 2° to 8°C (36° to 46°F) in the carton to preserve potency. Protect the medicine from light. Do not freeze it.

How much does Cisatra (Cisatracurium Besylate) cost in India?

Cisatracurium Besylate cost in India is competitively reasonable and may vary depending on the supplier and region. To purchase it legally and hassle-free, get in touch with us today. Call us at (+91) 8130290915 or our TOLL-FREE Number 1800-889-1064. You can also email us at info@indiangenericmedicines.com for more details. We’re here to assist you.

Where can I get Cisatra (Cisatracurium Besylate) at the best Price?

Order Cisatra at the best price today. We request you to Call/WhatsApp us at (+91) 8130290915 or dial our TOLL-FREE: 1800-889-1064 or Write us at info@indiangenericmedicines.com. We are committed to providing you with the best Cisatracurium price from India. That is why we’ll match the cost or price of any existing facilitators/suppliers/distributors in the market who require a medical prescription.

Is Cisatra (Cisatracurium Besylate) available in India?

Cisatra is a (prescription medicine, doctor-prescribed medication, or health care professional-prescribed drug) pharmaceutical drug that can be legally dispensed against a medical prescription. Cisatra can be made available through India’s authorized distributor network. (Hyderabad, Mumbai, Bangalore, Ahmedabad, Delhi, Kolkata, Chennai, Pune, etc.).

Can You Send the Cisatra (Cisatracurium Besylate) to Foreign Destinations?

Buy generic Cisatra online at the best/lowest price from a leading supplier. Indian Generic Medicines (IGM) can assist in the delivery of Cisatra; doctor-prescribed medication to Australia, Philippines, Brazil, the USA, Saudi Arabia, Canada, the UK, Thailand, Kazakhstan, Sri Lanka, China, Uzbekistan, Zambia, France, Germany. Pakistan, Singapore, Afghanistan, Malaysia, Kuwait, South Africa, Hong Kong, UAE, Turkey, Qatar, Japan, Nepal, and many other countries.

What is the procedure to buy Cisatra (Cisatracurium Besylate) from Indian Generic Medicines?

Patients can just fill out the order form or send mail to info@indiangenericmedicines.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008891064. We will reply ASAP with the details of the Cisatracurium injection price and the procurement procedure.
Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy Cisatra (Cisatracurium Besylate) online from India?

Yes, one can buy Cisatracurium online from India-based Indian Generic Medicines (IGM) if it is not (yet) registered or is unavailable in their respective country. We can facilitate the supply/export of Cisatra 10 mg/5mL or 20 mg/10mL injections through legal channels.