Panitumumab 100 MG/5 mL Injection

Vectibix (Panitumumab 100 MG/5 mL Injection)

Brand Name: Vectibix
API: Panitumumab
Packaging: Single-Dose Vials
Strength: Injection: 100 mg/5 mL (20 mg/mL)
Manufacturer: Dr Reddy’s Laboratories

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Description

General Information:

Panitumumab 100 mg/5 mL injection is an anticancer medication that belongs to the class of epidermal growth factor receptor (EGFR) inhibitors. It is primarily used in the treatment of metastatic colorectal cancer—a type of cancer that begins in the colon or rectum and then spreads to other parts of the body. By targeting the EGFR pathway, this therapeutic drug helps to slow the growth and spread of cancer cells, offering a specialized approach to managing this advanced stage of colorectal cancer. This drug is a key component in the therapeutic arsenal against metastatic colorectal cancer.

 

Dosage and Side Effects: 

The recommended dosage of Panitumumab for treating metastatic colorectal cancer is 6 mg/kg, given via intravenous (IV) infusion over 60 minutes every 14 days. For patients weighing over 100 kg, the infusion time may be extended to 90 minutes. Panitumumab can be used as a standalone treatment or in combination with other chemotherapy agents. Adjustments to the dosage or discontinuation of the treatment may be necessary if infusion-related reactions or skin toxicities occur. It is essential to consult with a healthcare provider (HCP) for tailored dosage advice and management throughout the treatment process

The most commonly reported side effects of Panitumumab 100 mg/5 mL injection are skin rash, itching, dry skin, nail changes, diarrhea, fatigue, nausea, and low magnesium levels.

Warning and Precautions

  • Treatment with Panitumumab may cause severe dermatologic reactions, including acneiform dermatitis, erythema, and skin exfoliation. Monitor patients regularly for dermatologic toxicities, and use topical or systemic therapies as appropriate. Dose modifications may be required in severe cases.
  • Hypomagnesemia, hypocalcemia, and hypokalemia can occur during therapy with Panitumumab. Regular monitoring of electrolytes is essential, particularly magnesium levels. Electrolyte repletion may be necessary to avoid complications.
  • Infusion reactions, including fever, chills, dyspnea, and hypotension, have been reported with the administration of this therapeutic drug. Pre-medicate patients with antihistamines and corticosteroids if needed, and monitor during the infusion. Interrupt or discontinue the infusion if severe reactions occur.
  • Panitumumab 100 mg/5 mL, when used in combination with chemotherapy, may increase the risk of acute renal failure. Close monitoring of renal function is recommended, especially in patients with pre-existing renal impairment. Discontinue treatment if signs of worsening renal function occur.
  • This medicine has been associated with the development of pulmonary fibrosis and interstitial lung disease (ILD), which can be fatal. Patients should be closely monitored for signs and symptoms of ILD, such as new or worsening respiratory symptoms. Discontinue treatment in patients who develop ILD or experience significant respiratory symptoms.
  • Vectibix 100 mg/5 mL injection can increase the risk of photosensitivity reactions, particularly in sun-exposed areas. Patients should be advised to avoid direct sunlight and to use protective clothing and sunscreen when outdoors. If photosensitivity reactions occur, treatment may need to be interrupted or discontinued depending on severity.
  • Ocular toxicities, including keratitis and ulcerative keratitis, have been reported with the use of this therapeutic drug. Patients should be monitored for signs and symptoms of ocular toxicity, such as eye pain, redness, and visual disturbances. If severe ocular toxicities occur, prompt evaluation by an ophthalmologist and discontinuation of treatment may be necessary.
  • Panitumumab can cause harm to a fetus when administered to a pregnant woman. Women of childbearing potential should be advised to use effective contraception during treatment and for at least 2 months following the last dose. Pregnancy status should be verified before initiating therapy.

FAQ's

What is Vectibix?

Vectibix is an Indian generic brand that contains Panitumumab as an active pharmaceutical ingredient (API). It falls under epidermal growth factor receptor (EGFR) inhibitors and is used for treating metastatic colorectal cancer.

How is Panitumumab administered? 

The proposed dosage of Panitumumab is administered as an intravenous (IV) infusion, typically over 60 minutes, every two weeks. The dosage is based on body weight, and the infusion rate may vary.

How should I store Panitumumab?

Store this therapeutic drug in a refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light and keep in the original packaging until ready to use.

How much does Panitumumab cost in India?

Panitumumab 100 mg/5 mL cost in India is competitively reasonable and may vary depending on the supplier and region. To buy it legally and hassle-free, get in touch with us today. Call us at (+91) 8130290915 or our TOLL-FREE Number 1800-889-1064. You can also email us at info@indiangenericmedicines.com for more details. We’re here to assist you.

Where can I get Panitumumab at the best Price? 

Order Panitumumab at the best price today. We request you to Call/WhatsApp us at (+91) 8130290915 or dial our TOLL-FREE: 1800-889-1064 or Write us at info@indiangenericmedicines.com. We are committed to providing you with the best Panitumumab price from India. That is why we’ll match the cost or price of any existing facilitators/suppliers/distributors in the market who require a medical prescription.

Is Panitumumab available in India?

Panitumumab 100 mg/5 mL is a (prescription medicine, doctor-prescribed medication, or health care professional-prescribed drug) pharmaceutical drug that can be legally dispensed against a medical prescription. Panitumumab can be made available through India’s authorized distributor network. (Hyderabad, Mumbai, Bangalore, Ahmedabad, Delhi, Kolkata, Chennai, Pune, etc.). 

Can You Send the Panitumumab to Foreign Destinations?

Buy generic Panitumumab online at the lowest price from a leading supplier. Indian Generic Medicines (IGM) can assist in the delivery of Panitumumab; doctor-prescribed medication to Australia, Philippines, Brazil, the USA, Saudi Arabia, Canada, the UK, Thailand, Kazakhstan, Sri Lanka, China, Uzbekistan, Kenya, Morocco, Zambia, France, Germany. Pakistan, Singapore, Afghanistan, Malaysia, Kuwait, South Africa, Hong Kong, UAE, Turkey, Qatar, Japan, Nepal, and many other countries.

What is the procedure to buy Panitumumab from Indian Generic Medicines? 

Patients can just fill out the order form or send mail to info@indiangenericmedicines.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008891064. We will reply ASAP with the details of the Panitumumab injection price and the procurement procedure.

Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy Panitumumab online from India?

Yes, one can buy Panitumumab online from India-based Indian Generic Medicines (IGM) if it is not (yet) registered or is unavailable in their respective country. We can facilitate the supply/export of generic Panitumumab 100 mg/5 mL injections through legal channels. 

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