Pemetrexed Injection

API: Pemetrexed Disodium
Packaging: Single Dose Vial
Strength: 500 mg/100 mg vial for injection

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Description

Introduction to Pemetrexed Injection

Uses of Medicine: Pemetrexed 500 mg or 100 mg vial for injection, a folate analog metabolic inhibitor is supplied generically under the brand Pemeplast. Patients, Healthcare Professionals, or Hospitals can buy Pemetrexed 500 mg/100 mg injections online from India through Indian Generic Medicines (a trusted Pemetrexed Injection Supplier, Exporter, and Contract Manufacturer in India) for the management and treatment of:

  • Locally Advanced or Metastatic Nonsquamous Non-Small Cell Lung Cancer: Pemetrexed 500 mg/100 mg injection, in combination with cisplatin, is used for the initial treatment of patients with locally advanced or metastatic nonsquamous non-small cell lung cancer (NSCLC). It is also used as a maintenance therapy for patients whose disease has not progressed after four cycles of platinum-based first-line chemotherapy. Additionally, This medicine is used as a single-agent treatment for patients with locally advanced or metastatic nonsquamous non-small cell lung cancer (NSCLC) who have previously undergone chemotherapy.
  • Malignant Pleural Mesothelioma (Cancers of the Lungs and Chest): Pemetrexed injection, in combination with cisplatin is used for the treatment of patients with malignant pleural mesothelioma whose disease is unresectable or who are otherwise not candidates for curative surgery.

Limitations of Use: Pemetrexed 500 mg/100 mg injection is not approved for the treatment of patients with squamous cell non-small cell lung cancer.

Pemetrexed injection is given alone or along with another anticancer medicine, such as cisplatin. Your healthcare provider (HCP) may also prescribe corticosteroids, folic acid, and vitamin B12. These help to reduce the side effects. Blood tests will be done before each infusion. These tests check if your kidney and liver functions are normal. They also check if you have enough blood cells to receive this medicine.

Before starting treatment with 500 mg/100 mg injection, inform your doctor about any past or current medical conditions. This includes kidney problems, heart disorders, or fluid buildup in the lungs. Tell your healthcare provider (HCP) if you recently had radiotherapy. Also, report if you have taken or plan to take any vaccinations before this treatment.

Dosage & Side Effects

Combination Use in Non-Small Cell Lung Cancer (NSCLC) and Mesothelioma: The recommended dose of Pemetrexed injection is 500 mg/m2 administered as an intravenous (IV) infusion over 10 minutes on Day 1 of each 21-day cycle. The recommended dose of cisplatin is 75 mg/m2 infused over 2 hours beginning approximately 30 minutes after the end of Pemetrexed administration. Patients should receive appropriate hydration before and/or after receiving cisplatin.
Single-Agent Use in Non-Small Cell Lung Cancer: The recommended dose of Pemetrexed is 500 mg/m2 administered as an intravenous (IV) infusion over 10 minutes on Day 1 of each 21-day cycle. Pemetrexed dose reductions or discontinuation may be required depending on toxicities from the preceding cycle of therapy.

The most commonly reported side effects of Pemetrexed injections as a single-agent use are nausea, fatigue, and anorexia. Additional common side effects when used in combination with cisplatin include anemia, vomiting, neutropenia, leukopenia, thrombocytopenia, stomatitis/pharyngitis, and constipation

Warning and Precautions

  • Before commencing Pemetrexed 500 mg/100 mg treatment, patients are prescribed folic acid and vitamin B12 as these have been shown to ease severe side effects. Moreover, physicians may also recommend corticosteroids to mitigate any potential skin reactions. While it is not obligatory to premedicate, doing so greatly improves the experience of the treatment.
  • Pemetrexed is capable of reducing blood cell production which can result in anemia, as well as increase the risk of infections and unexplained bruising. For this reason, patients are expected to have blood work done periodically. If they notice any unusual changes such as fever, extreme fatigue, or abnormal bleeding, they should consult with their doctors as they may be dealing with something far more serious.
  • Using Pemetrexed in patients with kidney problems should be approached with caution and close surveillance. The drug is excreted via the kidneys, so if their function is impaired, it may result in more harm than good. Staying hydrated and adhering to doctor’s orders will aid in minimizing health risks and complications, so it is something that should be done.
  • During Pemetrexed therapy, the physician will regularly monitor the patient’s blood cell counts, the state of their kidneys, and the condition of the liver, hence blood work will be necessary. These strategies assist the doctor in making modifications to avoid harmful consequences from the medications. Adhering to all necessary lab tests is paramount for treatment safety.
  • Undue pericardial effusion or ascitic fluid may lead to increased systemic toxicity of pemetrexed 100 mg/500 mg injection. Physicians may have to drain the fluid before initiation of therapy. Unusual swellings, breathing problems, or rapid weight changes should be attended to at once as they can be indicative of amiss health status.
  • Pregnant women must steer clear of this medication as it has proven harmful to the fetus. Pemetrexed is recommended not to be used by pregnant women using this medicine. Effective birth control has to be maintained throughout this procedure and for an indefinite period post-therapy. Seek medical consultation before tissue damage reconstruction after therapy.
  • There is potential that a nursing child might be affected by this medicine since pemetrexed can spread via breast milk. Therefore, breastfeeding should be discontinued throughout the duration and even for some time after the treatment is completed. All treatment options have to be discussed with physicians so that the mother remains safe and the child isn’t harmed.

FAQ's

What is Pemeplast?

Pemeplast is an Indian generic brand that contains Pemetrexed Disodium as its active ingredient. This generic medicine is commonly available in 500 mg/100 mg injections and is primarily used for the treatment of non-small cell lung cancer and malignant pleural mesothelioma (cancers of the lungs and chest).

How are Pemetrexed Disodium 500 mg/100 mg injections administered?

The recommended dosage of Pemetrexed 500 mg/100 mg injection is administered as intravenous (IV) administration.

How should I store Pemetrexed 500 mg/100 mg injections?

Store Pemetrexed 500 mg/100 mg injections at 25°C (77°F); excursions permitted to 15 to 30°C (59 to 86°F).

How much does Pemetrexed 500 mg/100 mg injection cost in India?

Pemetrexed 500 mg/100 mg injections are available in India at competitive and reasonable prices, though the cost may vary depending on the supplier and location. For those looking to buy Pemetrexed online legally and without hassle, Indian Generic Medicines (IGM) offers an easy and reliable solution. To inquire about the current Pemetrexed 500 mg/100 mg price in India, simply call us at +91 8130290915 or dial our TOLL-FREE Number 1800-889-1064. You can also email us at info@indiangenericmedicines.com for detailed pricing information and assistance.

Where can I get Pemetrexed 500 mg/100 mg injections at the best price?

To ensure you receive Pemetrexed at the most competitive price, reach out to Indian Generic Medicines (IGM) today. We are committed to offering the best prices for Pemetrexed from India. We can match or beat the cost offered by other suppliers or distributors in the market. Contact us via Call/WhatsApp at +91 8130290915, or use our TOLL-FREE Number 1800-889-1064. Alternatively, you can email us at info@indiangenericmedicines.com. Please note that a valid medical prescription is required to purchase Pemetrexed injection.

Are Pemetrexed 500 mg/100 mg injections available in India?

Yes, Pemetrexed 500 mg/100 mg injections are available in India as a prescription medication. This oral pharmaceutical drug can be legally obtained through India’s authorized distributor network, which spans major cities such as Hyderabad, Mumbai, Bangalore, Ahmedabad, Delhi, Kolkata, Chennai, and Pune. To buy generic Pemetrexed online from India, a valid prescription from a healthcare professional (HCP) is required. Indian Generic Medicines (IGM) can assist you in sourcing generic Pemetrexed from India’s top suppliers.

Can you send Generic Pemetrexed 500 mg/100 mg injections to foreign destinations?

Indian Generic Medicines (IGM) specializes in the export and delivery of generic Pemetrexed 500 mg/100 mg injections at the lowest prices. We facilitate the shipment of Pemetrexed injections to various countries, including but not limited to UAE, Australia, the USA, Saudi Arabia, Canada, the UK, Germany, France, Belgium, Bulgaria, Brazil, Kenya, Japan, and South Africa. Whether you are located in Australia, North America, South America, Eastern Europe, Western Europe, the Middle East, Africa, Central America, or Asia, IGM can assist in delivering generic Pemetrexed as per your requirements. For more information on international shipping options, contact us today.

What Is the procedure for buying Pemetrexed 500 mg/100 mg injection from Indian Generic Medicines?

To buy Pemetrexed injections online from India through Indian Generic Medicines (IGM), patients need to fill out the order form or send an email to info@indiangenericmedicines.com. Alternatively, you can send a WhatsApp message to +91 8130290915 or call our TOLL-FREE Number 1800-889-1064. After receiving your inquiry, we will provide you with the details regarding the Pemetrexed 500 mg/100 mg price in India and the procurement procedure. Please note that your order will only be confirmed once we receive a valid prescription from your physician.

Is it safe to buy Pemetrexed 500 mg/100 mg injections online from India?

Yes, buying Pemetrexed injections online from India through Indian Generic Medicines (IGM) is safe, especially if the drug is not registered or unavailable in your country. IGM facilitates the legal export of Pemetrexed 500 mg/100 mg injections to various countries. We ensure that you get genuine therapeutic drugs at the best price. Our service ensures compliance with all necessary regulations, providing a secure and reliable way to access generic Pemetrexed from India.