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Ertapenem Injection

  • Medicine name- Gerta
  • API- Ertapenem
  • Pack Size- 1 ml  single dose vial
  • Strength- 1gm
  • Manufactured by- Zydus Cadila
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Description

Ertapenem 1gm injection is a penem antibiotic used to treat moderate-to-severe infections resulting from sensitive bacteria in both adult and pediatric patients (3 months of age and up):

  • Complicated intra-abdominal infections.
  • Community-acquired pneumonia.
  • complicated UTIs, such as pyelonephritis for example.
  • Acute pelvic infections including septic abortion, postpartum endomyometritis, and post surgical gynecologic infections.
  • complex infections of the skin and skin structure, such as infections of the diabetic foot that do not involve osteomyelitis.
  • Adults undergoing elective colorectal surgery can utilize Gerta injection to prevent surgical site infections.

Dosage and Side Effects

Ertapenem can be given through intravenous infusion for a maximum of 14 days or via intramuscular injection for up to 7 days. When administered intravenously, it should be slowly infused over a 30-minute period. The 1 gm dose of ertapenem through intramuscular injection can be an alternative treatment for infections where this type of therapy is suitable.

For moderate to severe infections caused by susceptible bacteria:

  • Adults and patients aged 13 years and above are typically given a 1-gram dose once daily either intravenously or intramuscularly.
  • Patients aged 3 months to 12 years receive a dose of 15 mg/kg twice daily (not exceeding 1 g/day intravenously or intramuscularly).

For preventive measures in adults undergoing colorectal surgery, a single 1-gram dose is recommended, administered one hour before the procedure.

Important to note: Do not mix ertapenem 1gm injection with other medications or use diluents containing dextrose (glucose).

The most frequently reported side effects of Ertapenem are:

  • In adults: complications at the infusion site, diarrhea, nausea, and headaches.
  • In pediatric patients: diarrhea, vomiting, and pain at the injection site.

Warning and Precautions

  • Sometimes, severe allergic reactions can happen with medicines like ertapenem, and these reactions can be very serious or even fatal in rare cases. They’re more likely in people who have had allergic reactions to different things before.

  • Before starting ertapenem injections, it’s important to talk about any past allergic reactions you’ve had to similar antibiotics or other allergens.

  • Some people on ertapenem have experienced seizures or other issues with their brain and nervous system.

  • When giving ertapenem as an injection into the muscle, it’s important to be careful to avoid accidentally injecting it into a blood vessel.

  • Using antibiotics like ertapenem can sometimes lead to a problem called Clostridium difficile-associated diarrhea (CDAD), which can range from mild to very serious and even fatal. Antibiotics can change the balance of bacteria in the gut, leading to this problem.

  • Long-term use of ertapenem can cause growth of bacteria that are not affected by the medicine. So, it’s important to keep checking how you’re doing. If a new infection happens while you’re on this medicine, it needs to be treated correctly.

  • Using ertapenem without a confirmed bacterial infection or a clear need for preventive treatment might not help and could make bacteria more resistant to drugs.

  • Even though ertapenem is similar to other antibiotics, it’s a good idea to regularly check how well your organs, like your liver, kidneys, and blood system, are working if you’re taking it for a long time.

FAQ's

What conditions does Ertapenem treat?

Ertapenem is effective in treating severe bacterial infections in various parts of the body, including the skin, stomach, lungs, pelvis, and urinary tract. It’s also used to prevent infections in individuals undergoing specific types of surgery.

How is Ertapenem administered?

Ertapenem is available as a sterile lyophilized powder in single-dose vials. It can be administered either through intravenous infusion or by intramuscular injection. Your healthcare provider will determine the appropriate method based on your condition.

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