Buy Nevirapine 200 mg tablets Online at lowest Prices.

Nevirapine tablets

  • Medicine Name- Viramune 
  • API- Nevirapine
  • Packaging- 60 Tablets
  • Strength- 200 mg
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Description

Nevirapine 200 mg tablets, an NNRTI, is prescribed with other antiretroviral drugs to treat HIV-1 in adults and pediatric patients aged 15 days and older.

Limitations: Due to serious liver issues seen in trials, starting Nevirapineis is cautioned unless benefits outweigh risks in some instances:

    • Adult females with CD4+ cell counts over 250 cells/mm3
    • Adult males with CD4+ cell counts over 400 cells/mm3
    • Liver issues, both fatal and non-fatal, have been observed in Nevirapine users. It’s advised to stop immediately if signs of hepatitis or elevated liver enzymes with rash or other systemic symptoms appear. Restarting after recovery is not recommended.
    • Fatal and non-fatal skin reactions like Stevens-Johnson syndrome have been reported. Cease use if severe skin problems or rash with systemic symptoms occur. Immediate checks for liver enzyme levels are necessary for those with inflammation within the first 18 weeks of treatment. Restarting after recovery is discouraged.
    • Vigilant monitoring is crucial, especially in the initial 6 weeks of the 18-week therapy period due to higher risk.

Dosage and Side Effects of Nevirapine Tablets

  • Follow the strict 14-day lead-in period to reduce rash frequency.
  • If a rash occurs during this period, hold off on the dose increase until it resolves. The lead-in dosing shouldn’t exceed 28 days.
  • If dosing is paused for over 7 days, resume with the 14-day lead-in dosing.

A rash is the most common side effect. In adults, it occurs in 15% of cases compared to 6% with a placebo, with severe rash seen in 2%. Among pediatric subjects, rash occurred in 21% of cases.

Warning and Precautions of Nevirapine Tablets

  • Patients with moderate or severe liver issues (Child-Pugh Class B or C).
  • Not recommended for occupational or non-occupational post-exposure prophylaxis (PEP).
  • There were reports of cases of Immune reconstitution syndrome in patients treated with combination antiretroviral therapy, including Nevirapine 200 mg. During the initial phase of combination antiretroviral treatment, patients whose immune system responds may develop an inflammatory response to indolent or residual opportunistic infections, which may necessitate further evaluation and treatment. 

FAQ's

What pregnancy category has the FDA assigned to nevirapine?

FDA Pregnancy Category: Not categorized. Risk assessment suggests minimal likelihood of malformations with the drug’s use in pregnant women.

What is nevirapine’s bioavailability?

Nevirapine tablet is highly absorbed (over 90%) when taken orally by both healthy individuals and adults with HIV-1 infection. In healthy adults, a single dose of a 50 mg tablet shows an absolute bioavailability of 93 ± 9%, while an oral solution displays 91 ± 8%.

Under which drug classification does nevirapine fall?

Nevirapine tablet belongs to the class of medications known as non-nucleoside reverse transcriptase inhibitors (NNRTIs). Its mechanism involves reducing HIV levels in the bloodstream.

Is nevirapine known for causing liver issues?

There have been severe and fatal cases of nevirapine-related hepatotoxicity reported, including instances necessitating emergency liver transplants. Extensive case studies often list nevirapine among the significant causes of acute liver failure induced by drugs.

Is nevirapine an inducer or inhibitor of enzymes?

CYP2B6 and 2D6 minimally process nevirapine and have mild inhibitory effects on CYP1A2, 2D6, and 3A4 enzymes. It is a significant subject to an inducer of CYP3A4 and a potent inducer of CYP2B6. Consequently, there’s a potential for numerous clinically relevant drug interactions.

What is the procedure to buy Nevirapine from Indian Generic Medicines? 

Patients can fill out the order form or send mail to info@indiangenericmedicines.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial the TOLL-FREE Number: 18008891064. We will reply ASAP with the details of Nevirapine 200 mg price tablet as well as the procurement procedure.

Note:- The order will be confirmed only after the valid receipt of the prescription from the Doctor.

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