• Medicine Name- Rybelsus
  • API- Semaglutide
  • Packaging- 10 tablets
  • Strength- 3 mg/7 mg/ 14 mg
  • Manufactured By: Novo Nordisk
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Semaglutide Tablets is a glucagon-like peptide-1 (GLP-1) receptor agonist and once-daily antidiabetic medication used along with diet and exercise to improve blood sugar (glucose) in adult individuals with type-2 diabetes.

Semaglutide oral tablet is not for use in those with type 1 diabetes and those who have had pancreatitis. Do not use this drug as first-line therapy for all those not adequately controlled on diet and exercise.

Dosage and Side Effects

The recommended dosage of Semaglutide must be taken at least 30 minutes prior to the first food, beverage, or other oral medicines of the day with no excess than four ounces of plain water only. Swallow tablets of Semaglutide whole. It is not advisable to split, crush, or chew tablets.  Start Semaglutide therapy with 3 mg once daily for one month (30 days).

The Semaglutide tablets 3 mg dose is for treatment initiation and is not promising for glycemic management. After completing one month (30 days) on the 3 mg, the dose can be increased to 7 mg once daily. The dose can be enhanced to 14mg once daily in case additional glycemic management is required following at least one month (30 days) on the 7mg dose. Avoid using two 7 mg tablets to reach a 14 mg dose. In case a dose is missed or skipped, the missed or skipped dose should be left out, and the next dose of Semaglutide should be taken the very next following day.

The most commonly reported side effects of Semaglutide include: abdominal pain, nausea, diarrhea, constipation, decreased appetite, and vomiting.

Warning and Precautions

    • Use of semaglutide tablets 14mg/7mg/3mg are restricted in all the individuals with a personal or known family history of medullary thyroid carcinoma (MTC) or in all the individuals with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Patients must be counseled for the potential risk for MTC with the use of Semaglutide and let them know about symptoms of thyroid tumors (e.g. dysphagia, dyspnea, a mass in the neck, persistent hoarseness). 
    • After initiating Semaglutide therapy, observe patients precisely for manifestations of pancreatitis (including severe abdominal pain, sometimes radiating to the back and which may or may not be accompanied by puking). In case pancreatitis is suspected, discontinue Semaglutide treatment and start suitable management; if confirmed, do not start Semaglutide treatment.
    • Prompt enhancement in glucose control has been linked with a temporary worsening of diabetic retinopathy. The effect of extended glycemic management with semaglutide 7 mg, 14 mg, or 3 mg therapy on complications of diabetes that affects the eyes has not been evaluated. Those with a history of diabetic retinopathy must be monitored for headway of diabetic retinopathy.
    • The potential of hypoglycemia occurs when Semaglutide is used along with insulin secretagogues (sulfonylureas) or insulin. Individuals may require a reduced dose of the secretagogue or insulin to scale down the probability of hypoglycemia.

    Cases of acute kidney injury and chronic renal failure (sometimes requiring hemodialysis) may occur in all those treated with GLP-1 receptor agonists, including semaglutide. Monitor renal function when starting or escalating Semaglutide tablets dosage in those with gastrointestinal reactions.


What is Semaglutide?

Once-daily Semaglutide is the first and only GLP-1 pill and prescription medicine used in conjunction with diet and exercise to improve blood sugar and A1C in adults with type 2 diabetes.

What dosage strengths Semaglutide is supplied?

Semaglutide is supplied in three standard dosage strengths, which are as follows:

  • semaglutide 14 mg tablets
  • semaglutide 7 mg tablets
  • semaglutide 3 mg tablets

How do I take Semaglutide?

Semaglutide is commercially available as a tablet for oral administration. Take on an empty stomach once you first wake up. Wait around 30 minutes prior to eating, drinking, or taking other oral medicines.

Will Semaglutide affect my weight?

  • While not developed for weight loss, Semaglutide may help you lose some weight.

How much does Semaglutide Tablet cost in India?

Semaglutide tablets cost in India is low and can vary. If you are looking to buy this medicinal product online at the best price from India, then Indian Generic Medicines  (IGM) can help facilitate the supply of Semaglutide in India and other countries, where the drug is not available.